Protein Alignment CG9289 and Nlgn3

DIOPT Version :10

• Sequence 1: NP_609245.1
• Gene: CG9289 / 34195
• FlyBaseID: FBgn0032058
• Length: 674
• Species: Drosophila melanogaster
• Sequence 2: NP_599163.2
• Gene: Nlgn3 / 171297
• RGDID: 621119
• Length: 848
• Species: Rattus norvegicus
• Alignment Length: 645
• Identity: 184/645 - (28%)
• Similarity: 270/645 - (41%)
• Gaps: 163/645 - (25%)

  Fly    84 GRLRGR--TLTTDWTGQKIMQFLDIPYGK----AERFRPAEPAPSWKGVLPA-HRP-------HA 134
            |:|||.  .|.::..| .:.|:|.:||..    .:||.|.||.|||.|:..| |.|       |.
  Rat    49 GKLRGARVPLPSEILG-PVDQYLGVPYAAPPIGEKRFLPPEPPPSWSGIRNATHFPPVCPQNIHT 112

  Fly   135 GCPSIQ-------DL-IVFAKLEEDGFDVEDCLRLSV------------------NTK------- 166
            ..|.:.       :| ||...::|..   ||||.|:|                  |.|
  Rat   113 AVPEVMLPVWFTANLDIVATYIQEPN---EDCLYLNVYVPTEDVKRISKECARKPNKKICRKGGS 174

  Fly   167 --AMEGKSL-----------------PVMVYIHGDFFYDG------DSVEAAPGYLLEHDVVLVS 206
              ..:|:.|                 ||||||||..:.:|      .||.|:.|     :|::::
  Rat   175 GAKKQGEDLADNDGDEDEDIRDSGAKPVMVYIHGGSYMEGTGNMIDGSVLASYG-----NVIVIT 234

  Fly   207 VRYRLGPFGFLSTLTDEMPGNAAVTDIILALKWVQQHIASFGGDPQRVTLFGQVGGAALVNVLTL 271
            :.||:|..|||||......||..:.|.|.||:||.::||.|||||:|:|:||...||:.|::|||
  Rat   235 LNYRVGVLGFLSTGDQAAKGNYGLLDQIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTL 299

  Fly   272 SPAVPAGLFHRVIYQSGTALSPAFITDAPLGATKAIGRIAGCKQSTKVDQLNKCLNRLNATMLLA 336
            |.. ..|||.|.|.|||:|||...:...|:..|..:....||.....||.:: ||.:.:|..|
  Rat   300 SHH-SEGLFQRAIIQSGSALSSWAVNYQPVKYTSLLADKVGCNVLDTVDMVD-CLRQKSAKEL-- 360

  Fly   337 AFSVHGENQPSLSGGAYGGVQLVIGGPSGILPEHPGRLLAAEKFQAYPTMGGSVKHGGTFMLRDI 401
               |..:.||:....|:|.   ||.|  .::|:.|..|:...:|..|..|.| |..|....
  Rat   361 ---VEQDIQPARYHVAFGP---VIDG--DVIPDDPEILMEQGEFLNYDIMLG-VNQGEGLK---- 412

  Fly   402 FADIFNETILD--DTMTG-------RQYIDTIIEQANGADPSGSWKEFSDEEIFTQ-NDVKNGTF 456
                |.|.::|  |.::|       ..::|.:.....|.|......:|    ::|. .|..|...
  Rat   413 ----FVEGVVDPEDGVSGTDFDYSVSNFVDNLYGYPEGKDTLRETIKF----MYTDWADRDNPET 469

  Fly   457 KRLTPGLIDLCSTISLKNPVLLVLQANAKKLPNSTYLYSFDYEGEQNRYATGEDEA--NFVPFDM 519
            :|.|  |:.|.:......|.::....:| :..:.||.|:|.:..:........|.|  :.||:..
  Rat   470 RRKT--LVALFTDHQWVEPSVVTADLHA-RYGSPTYFYAFYHHCQSLMKPAWSDAAHGDEVPYVF 531

  Fly   520 GVSL---TDDNLYLFPWPRFLALN-SNRDLKVARRMVALWTSFATTGVPQAPGLP---------- 570
            ||.:   ||    |||      .| |..|:.::..::..||:||.||.|..| :|
  Rat   532 GVPMVGPTD----LFP------CNFSKNDVMLSAVVMTYWTNFAKTGDPNKP-VPQDTKFIHTKA 585

  Fly   571 ------AWPAMNDETGPYMKIDRTVSFGDNYLDEYRIAVEEA------KHGYNLVNDEYY 618
                  ||...|.....|:.|    .......|.|| |.:.|      .|.|||.:..:|
  Rat   586 NRFEEVAWSKYNPRDQLYLHI----GLKPRVRDHYR-ATKVAFWKHLVPHLYNLHDMFHY 640

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9289	NP_609245.1	COesterase	71..598	CDD:395084	174/617 (28%)
Nlgn3	NP_599163.2	COesterase	40..624	CDD:395084	179/627 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	169..195		2/25 (8%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	645..691