Protein Alignment CG9289 and ache

DIOPT Version :10

• Sequence 1: NP_609245.1
• Gene: CG9289 / 34195
• FlyBaseID: FBgn0032058
• Length: 674
• Species: Drosophila melanogaster
• Sequence 2: NP_571921.1
• Gene: ache / 114549
• ZFINID: ZDB-GENE-010906-1
• Length: 634
• Species: Danio rerio
• Alignment Length: 658
• Identity: 181/658 - (27%)
• Similarity: 266/658 - (40%)
• Gaps: 145/658 - (22%)

  Fly    72 EPKVFTTTVPDLGRLRGRTLTTDWTGQKIMQFLDIPY-----GKAERFRPAEPAPSWKGVLPAHR 131
            ||.:...|  .|||::|..|... ....::.||.|||     || .||:.|||...|..|..|..
Zfish    26 EPDLVVAT--RLGRVQGTRLPVP-DRSHVIAFLGIPYAEPPIGK-RRFKRAEPKKPWNNVFEAKE 86

  Fly   132 PHAGCPSIQDLIVFAKLEEDGFD-----------VEDCLRLSV-NTKAMEGKSLPVMVYIHGDFF 184
            ....|      ..|......||.           .||||.|:| .......::|.|||:|:|..|
Zfish    87 FSNAC------YQFVDTSYPGFPGIEMWNPNRVMSEDCLYLNVWVPPTPRPQNLTVMVWIYGGGF 145

  Fly   185 YDG-DSVEAAPGYLLEH--DVVLVSVRYRLGPFGFLS-TLTDEMPGNAAVTDIILALKWVQQHIA 245
            |.| .|::...|..|.:  .||:||:.||:|.||||: ..:.:.|||..:.|..|||:|||::|.
Zfish   146 YSGSSSLDVYDGRYLAYTEKVVVVSMNYRVGAFGFLALNGSSDAPGNVGLYDQRLALQWVQENIH 210

  Fly   246 SFGGDPQRVTLFGQVGGAALVNVLTLSP-AVPAGLFHRVIYQSGTALSP-AFIT-DAPLGATKAI 307
            .|||:|::||:||:..|||.|.:..||| :.|  ||.|.|.|||...:| |.:| |.....|..:
Zfish   211 FFGGNPKQVTIFGESAGAASVGMHVLSPDSRP--LFTRAILQSGVPNTPWATVTFDEARRRTTKL 273

  Fly   308 GRIAGCKQSTKVDQLNKCLNRLNATML------------LAAFS----VHGENQPS-----LSGG 351
            |::.||......:.:: ||...:...|            |..||    |.|...|.     :|.|
Zfish   274 GKLVGCTWGNDTELID-CLRNKHPQELIDQEWQVLPWSSLFRFSFVPVVDGVFFPDTPDAMISSG 337

  Fly   352 AYGGVQLVIG-----GPSGILPEHPG------RLLAAEKFQAYPTMGGSVKHGGTFMLRDI---F 402
            .:...|:::|     |...:|...||      .|::.|.|.....||  |.|.....|..:   :
Zfish   338 NFKYTQILLGVNQDEGSYFLLYGAPGFSKDNESLISREDFLESVKMG--VPHANDIGLEAVILQY 400

  Fly   403 ADIFNETILDDTMTGRQYIDTIIEQANGADPSGSWKEFSDEEIFTQNDVKNGTFKRLTPGLIDLC 467
            .|..:|   ::....|..:|.|:...|...|   .:.|:  :.:.|....:.......||
Zfish   401 TDWMDE---NNGQKNRDAMDDIVGDQNVICP---LQHFA--KSYAQYAALHAQSSAAAPG----- 452

  Fly   468 STISLKN--PVLLVLQANAKKLPNSTYLYSFDYEGEQNRYATGEDEANFVPFDMGVSLTDDNLYL 530
             |:...|  |.    ..|:.....:.|||.||:......:          |..|||....:..::
Zfish   453 -TLGWGNSGPT----GYNSGNSHGAVYLYLFDHRASNLAW----------PEWMGVIHGYEIEFV 502

  Fly   531 FPWPRFLALN-SNRDLKVARRMVALWTSFATTGVPQAPGLPAWPAMNDETGPYMKIDRTVSFGDN 594
            |..|....|| :..:.|::||::..|.:||.||.|           |..|             |.
Zfish   503 FGLPLEKRLNYTAEEEKLSRRIMRYWANFARTGNP-----------NVNT-------------DG 543

  Fly   595 YLDEYR----IAVEEAKH-GYNL--------VNDEYYDLQEALLAASKLDSLNDANEEDEEDQDD 646
            .:|..|    .:..|.|| |.|.        :..::..|....|  .:|.::.| |.:|.|.|..
Zfish   544 TMDSRRRWPQFSANEQKHVGLNTEPMKVHKGLRTQFCALWNRFL--PRLLNITD-NIDDVERQWK 605

  Fly   647 AEGQRAAS 654
            .|..|.:|
Zfish   606 VEFHRWSS 613

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9289	NP_609245.1	COesterase	71..598	CDD:395084	163/587 (28%)
ache	NP_571921.1	COesterase	27..583	CDD:395084	169/622 (27%)
		AChE_tetra	598..631	CDD:430146	6/16 (38%)