Protein Alignment CG9289 and CEL

DIOPT Version :10

• Sequence 1: NP_609245.1
• Gene: CG9289 / 34195
• FlyBaseID: FBgn0032058
• Length: 674
• Species: Drosophila melanogaster
• Sequence 2: NP_001798.3
• Gene: CEL / 1056
• HGNCID: 1848
• Length: 753
• Species: Homo sapiens
• Alignment Length: 557
• Identity: 149/557 - (26%)
• Similarity: 226/557 - (40%)
• Gaps: 118/557 - (21%)

  Fly    97 GQKIMQFLDIPY-GKAERFRPAEPAPSWKGVLPAHRPHAGCPSIQDLIVFAKLEEDGFDVEDCLR 160
            |..:..|..||: ...:.....:|.|.|:|.|.|......|  :|..|.    ::..:..||||.
Human    44 GDSVDIFKGIPFAAPTKALENPQPHPGWQGTLKAKNFKKRC--LQATIT----QDSTYGDEDCLY 102

  Fly   161 LSV---NTKAMEGKSLPVMVYIHG---------------DFFYDGDSVEAAPGYLLEHDVVLVSV 207
            |::   ..:....:.||||::|:|               ::.|||:.: |..|     :|::|:.
Human   103 LNIWVPQGRKQVSRDLPVMIWIYGGAFLMGSGHGANFLNNYLYDGEEI-ATRG-----NVIVVTF 161

  Fly   208 RYRLGPFGFLSTLTDEMPGNAAVTDIILALKWVQQHIASFGGDPQRVTLFGQVGGAALVNVLTLS 272
            .||:||.|||||....:|||..:.|..:|:.||:::||:|||||..:||||:..|.|.|::.|||
Human   162 NYRVGPLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITLFGESAGGASVSLQTLS 226

  Fly   273 PAVPAGLFHRVIYQSGTALSPAFITDAPLGATKAIGRIAGCKQSTKVDQLNKCLNRLNATMLLAA 337
            | ...||..|.|.|||.||||..|...||...|.:....||...... ::.:||...:...|..|
Human   227 P-YNKGLIRRAISQSGVALSPWVIQKNPLFWAKKVAEKVGCPVGDAA-RMAQCLKVTDPRALTLA 289

  Fly   338 FSVHGENQPSLSGGAYGGVQLVIGGPSGILPEHPGRLLAAEKFQAYP------------TMGG-- 388
            :.|      .|:|..|..:..|     |.:|...|..:.|:....|.            .|.|
Human   290 YKV------PLAGLEYPMLHYV-----GFVPVIDGDFIPADPINLYANAADIDYIAGTNNMDGHI 343

  Fly   389 -------SVKHGGTFMLRDIFADIFNETILDDTMTGRQYIDTIIEQANGADPSGSWK-----EFS 441
                   ::..|...:..:.|..:.:|..:...:.|.:....:..::...|||...|     :|.
Human   344 FASIDMPAINKGNKKVTEEDFYKLVSEFTITKGLRGAKTTFDVYTESWAQDPSQENKKKTVVDFE 408

  Fly   442 DEEIFTQNDVKNGTFKRLTPGLIDLCSTISLKNPVLLVLQANAKKLPNSTYLYSFDYEGEQNRYA 506
            .:.:|            |.|..|.|...           :||||..  .||.|.|.:......|
Human   409 TDVLF------------LVPTEIALAQH-----------RANAKSA--KTYAYLFSHPSRMPVY- 447

  Fly   507 TGEDEANFVPFDMGVSLTDDNLYLFPWPRFLALNSNR--DLKVARRMVALWTSFATTGVPQA--P 567
                     |..:|....||..|:|..| |......|  |..|::.|:|.||:||.||.|..  .
Human   448 ---------PKWVGADHADDIQYVFGKP-FATPTGYRPQDRTVSKAMIAYWTNFAKTGDPNMGDS 502

  Fly   568 GLPA-WPAMNDETGPYMKIDRTV-------SFGDNYL 596
            .:|. |.....|...|::|.:.:       |...|:|
Human   503 AVPTHWEPYTTENSGYLEITKKMGSSSMKRSLRTNFL 539

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9289	NP_609245.1	COesterase	71..598	CDD:395084	149/557 (27%)
CEL	NP_001798.3	Heparin-binding	21..121		20/82 (24%)
		COesterase	26..542	CDD:395084	149/557 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	555..753
		17 X 11 AA tandem repeats, glycodomain, O-linked (mucin type)	559..745
		Mucin-like	584..677	CDD:464997
		Mucin-like	639..731	CDD:464997