DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9287 and Ces1h

DIOPT Version :9

Sequence 1:	NP_609244.1	Gene:	CG9287 / 34194	FlyBaseID:	FBgn0032057	Length:	625	Species:	Drosophila melanogaster
Sequence 2:	NP_001357759.1	Gene:	Ces1h / 75704	MGIID:	1922954	Length:	562	Species:	Mus musculus

Alignment Length:	587	Identity:	163/587 - (27%)
Similarity:	242/587 - (41%)	Gaps:	132/587 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 TLGSIQGKILETAWTKREVLQFVDVRYAEPPTGLHRFKAPRPIEPWEDVMDATAEKIGCPSVVSM 104
            |.|.:.||.:......:.|..|:.|.:|:||.|..||..|:|.|||..|.:||:    .|.:.|.
Mouse    29 THGKVLGKYISLEGFTQPVAVFLGVPFAKPPLGSLRFAPPQPPEPWSFVKNATS----YPPMCSQ 89

  Fly   105 DSL--RRLDDVL----------DVEDCLTMTITTP----NVTSRLPVLVYIHGEYL-------YE 146
            |::  :.::|::          ..||||.:.:.||    ..|:||||:|:|||..|       |:
Mouse    90 DAVLGQMVNDLIINNKEKIRLRFSEDCLYLNVYTPVDLMKNTNRLPVMVWIHGGGLVVGGASAYD 154

  Fly   147 GSNSEAPPDYLLEKDVVLVTPQYRLGPFGFLSTKTDEIPGNAGFLDIFLALQFVKHFIKYFGGDP 211
            |....|      .::||:||.||||..:||.||..:...||.|.||...||.:::..|..|||||
Mouse   155 GRTLSA------HENVVVVTIQYRLAIWGFFSTGDEHSRGNWGHLDQLAALHWIQDNIANFGGDP 213

  Fly   212 SRVTVAGQVGGAAIAHLLTLSPVVQRGLFHQVIYHSGSAIMPIFLEEDPRKHAQEIAKKADCKMV 276
            ..||:.||..|.....:|.|||:. :.|||:.|..||.........||.....::||..|.||..
Mouse   214 GSVTIFGQSAGGESVSVLVLSPLA-KNLFHRAISQSGVVFTSGLFMEDASSVTEQIAVTAGCKTT 277

  Fly   277 TVRDLNTCLMELTALELLTAFMEHALEKSDLGIGHTGGIQFTIGGPSG-VLPKHPYDLMLETNFS 340
            |...:..||.:.|..|||....:..|.|.|..........|......| ||||.|..::.|.||
Mouse   278 TSAVIVHCLRQKTEEELLEIMQKMNLFKLDAQENTKKNYPFLPTVLDGVVLPKAPEAILAEKNF- 341

  Fly   341 YPAMGGCPKNAGSRVLNEIVDNDFEGKIPDDEYNTYNYIDHVIRQTVGTDKTMLLTSFVTHD--- 402
                                             ||..||..:.:|..|....|:: .|...|
Mouse   342 ---------------------------------NTVPYIVGINKQEFGWTLPMIM-EFPPTDVKL 372

  Fly   403 --------------FFNRNLMEN-----------GTFDTLIPR--LIDVAGTLNHKLP-VLLALN 439
                          ||  |:.|:           ||.|.:..|  |:.:.|.:...:| |:::..
Mouse   373 DKKVISLFLRKLAYFF--NIPEDGIPVAIEKYSKGTDDPIQNRVWLLQLIGDVMFGIPSVIVSRG 435

  Fly   440 MNNKHNPDNTFLYSFDYAGEFNRYKEMDEETNLQSPFKAGVSLT----DEALYLFPYPEHVTRLS 500
            ..:...|  |::|.|.....|:  .|:..:|           :|    ||...:|..|......|
Mouse   436 HRDAGAP--TYMYEFQSRPSFS--SELKPKT-----------VTGDHGDEVYSVFGAPILREGSS 485

  Fly   501 RPDQSMAHRMVELWTNFVISGNPLGSARVGYWPPMTTLYGPYMRIDDTMTIGGNYFTEFSATLSD 565
            ..:.:::..|::.|.||..:|||.|.. :.:||......| |::|..|        |:.:..|.|
Mouse   486 EEEINLSKMMMKFWANFARNGNPNGQG-LPHWPEYNQKKG-YLQIGAT--------TQQAQGLKD 540

  Fly   566 EE 567
            :|
Mouse   541 KE 542

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9287	NP_609244.1	COesterase	31..558	CDD:278561	159/576 (28%)
Ces1h	NP_001357759.1	COesterase	24..546	CDD:365897	163/587 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832588
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740