DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9287 and Ces2g

DIOPT Version :9

Sequence 1:	NP_609244.1	Gene:	CG9287 / 34194	FlyBaseID:	FBgn0032057	Length:	625	Species:	Drosophila melanogaster
Sequence 2:	NP_932116.2	Gene:	Ces2g / 72361	MGIID:	1919611	Length:	560	Species:	Mus musculus

Alignment Length:	568	Identity:	164/568 - (28%)
Similarity:	243/568 - (42%)	Gaps:	105/568 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 WWQIV--SLLLVLQSVVESRVRGRQYDEEKDTIVELPTLGSIQGKILETAWTKREVLQFVDVRYA 67
            |...|  .|||:|     ..|:|  :|..:.:.:.....|.:||:::....||..|..|:.:.:|
Mouse     9 WLDAVFFGLLLLL-----GHVQG--HDSPETSPIRSTHSGQVQGRLIHVKDTKAGVHTFLGIPFA 66

  Fly    68 EPPTGLHRFKAPRPIEPWEDVMDATAEKIGCPS--VVSMDSLRRLDDVLD----VEDCLTMTITT 126
            :||.|..||..|...|||..|.|.|::...||.  .::|:.|:.|...|.    .||||.:.|.|
Mouse    67 KPPVGPLRFAPPEAPEPWSGVRDGTSQPAICPQNVTMNMEGLKELKLTLPPVSMSEDCLYLNIYT 131

  Fly   127 P---NVTSRLPVLVYIHGEYL-------YEGSNSEAPPDYLLEKDVVLVTPQYRLGPFGFLSTKT 181
            |   ...|.|||:|:|||..|       |:||...|      .:|||:|..|||||..||.||..
Mouse   132 PAHAQEGSNLPVMVWIHGGALTVGMASMYDGSVLAA------TEDVVVVAIQYRLGVLGFFSTGD 190

  Fly   182 DEIPGNAGFLDIFLALQFVKHFIKYFGGDPSRVTVAGQVGGAAIAHLLTLSPVVQRGLFHQVIYH 246
            :...||.||||...||::|:..|.:|||:|.|||:.|:..|........:|| :.:||||:.|..
Mouse   191 EHARGNWGFLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGISVSSHVVSP-MSKGLFHRAIME 254

  Fly   247 SGSAIMPIFLEEDPRKHAQEIAKKADCKMVTVRDLNTCLMELTALELLTAFMEHALEKSDLGIGH 311
            ||.|::|..:........|.:||.:.|:.:....|..||...:..|:|      |:.|:
Mouse   255 SGVALLPGTIFSFSEVVYQTVAKLSGCEAMDSEALVRCLRGKSEEEIL------AISKN------ 307

  Fly   312 TGGIQFTIGGPSG-VLPKHPYDLMLETNFSYPAMGGCPKNAGSRVLNEIVDNDFEGKIPDDEYNT 375
               .|...|...| .|||||.:|:...:| :|.    |...|       .:||..|.|......:
Mouse   308 ---FQMIPGVVDGEFLPKHPQELLASADF-HPV----PSIIG-------FNNDEYGWIVPKVIGS 357

  Fly   376 YNYIDHVIRQTV-----GTDKTMLLTSFVTHDFFNRNLMENGTFDTLIPRLIDVAGT-----LNH 430
            ...|..:.|:.:     .|...|:|....: |.    |||....|...|:.:.:..|     ...
Mouse   358 TQTIKGITRENLQAVLKDTAPQMMLPPECS-DL----LMEEYMEDIEDPKTLQIQFTEMMEDFMF 417

  Fly   431 KLPVLLALNMNNKHNPDNTFLYSFDYAGEF---NRYKEMDEETNLQSPFKAG-------VSLTDE 485
            .:|.|........|.|  .:.|.|.:...|   .|...::.:...:.||..|       ::||:|
Mouse   418 VIPSLQVAYFQRSHAP--VYFYEFQHQSSFLKDVRPPHVNADHGDEVPFVFGSFFWGMKLNLTEE 480

  Fly   486 ALYLFPYPEHVTRLSRPDQSMAHRMVELWTNFVISGNPLGSARVGYWP 533
                             ::.:..||::.|.||...||| .|..:.|||
Mouse   481 -----------------EKLLNRRMMKYWANFARHGNP-NSESLPYWP 510

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9287	NP_609244.1	COesterase	31..558	CDD:278561	155/540 (29%)
Ces2g	NP_932116.2	COesterase	31..539	CDD:278561	155/539 (29%)
Ces2g	NP_932116.2	Aes	72..>337	CDD:223730	100/291 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832737
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740