DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9287 and Ces2f

DIOPT Version :9

Sequence 1:	NP_609244.1	Gene:	CG9287 / 34194	FlyBaseID:	FBgn0032057	Length:	625	Species:	Drosophila melanogaster
Sequence 2:	NP_001073334.2	Gene:	Ces2f / 71903	MGIID:	1919153	Length:	561	Species:	Mus musculus

Alignment Length:	575	Identity:	159/575 - (27%)
Similarity:	239/575 - (41%)	Gaps:	96/575 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LLLVLQSVVESRVRGRQYDEEKDTIVELPTLGSIQGKILETAWTKREVLQFVDVRYAEPPTGLHR 75
            |:|:|      .|:|  .|..:.:.:.....|.::||.:.....|.....|:.:.:|:||.|..|
Mouse    18 LVLLL------HVKG--LDSSEASPIRNTHTGQVRGKFVHLTDIKAGAHNFLGIPFAKPPVGPLR 74

  Fly    76 FKAPRPIEPWEDVMDATAEKIGC---PSVVSMDSLRRLDDVLD----VEDCLTMTITTP---NVT 130
            |..|...|||..|.|.|::...|   ..:|:::.|:.:..:|.    .||||.:.|.||   ...
Mouse    75 FAPPEAPEPWSGVRDGTSQPAMCLQNDDIVNLEGLKIIKMILPPFSMSEDCLYLNIYTPAHAQEG 139

  Fly   131 SRLPVLVYIHG-------EYLYEGSNSEAPPDYLLEKDVVLVTPQYRLGPFGFLSTKTDEIPGNA 188
            |.|||:|::||       ..:|:||...|      .:|||:|..|||||..||.||..::..||.
Mouse   140 SNLPVMVWLHGGGLVAGMASMYDGSVLAA------TEDVVVVVTQYRLGIPGFYSTGDEQARGNW 198

  Fly   189 GFLDIFLALQFVKHFIKYFGGDPSRVTVAGQVGGAAIAHLLTLSPVVQRGLFHQVIYHSGSAIMP 253
            ||||...||.:|:..|..|||:|..||:.||..|........||||.| ||||:.|..||.|::|
Mouse   199 GFLDQTAALHWVQQNIANFGGNPDSVTLFGQSAGGTSVSFHVLSPVSQ-GLFHRAIMESGVALLP 262

  Fly   254 IFLEEDPRKHAQEIAKKADCKMVTVRDLNTCLMELTALELLTAFMEHALEKSDLGIGHTGGIQFT 318
            ..:.:.|.....::|..:.|:......|..||...:..|:|      |:.|:         .:|.
Mouse   263 TIIPDSPEMIFTKVANLSGCETSNSEALVRCLRGKSEAEIL------AMSKA---------FRFM 312

  Fly   319 IGGPSG-VLPKHPYDLMLETNFSYPAMGGCPKNAGSRVLNEIVDNDFEGKIPDDEYNTYNYIDHV 382
            .....| .||:||..|:...:| :|.    |...|       |:||..|.|....:.....|..:
Mouse   313 PAVVDGKFLPRHPKKLLASADF-HPV----PSIIG-------VNNDEYGWIIPKIFKFSQTIRKI 365

  Fly   383 IRQTVG-----TDKTMLLTSFVTHDFFNRNLMENGTFDTLIPRLIDVAGTLNHKLPVLLALNMNN 442
            .|..:.     |.:.|:|.|..........|.:.....||..:..::.|.....:|.|.......
Mouse   366 NRNNLKAIMKITTEQMMLPSECGDLLIEEYLRDTEDPWTLQMQFREMIGDFLIIIPALQVARFQR 430

  Fly   443 KHNPDNTFLYSFDYAGEFNRYKEMDEETNLQSPFKAGVSLTDEALYL----------FPYPEHVT 497
            .|.|  .:.|.|.:.....:|..         |:.......|| |||          |.:.....
Mouse   431 SHAP--VYFYEFQHRSSLLKYFR---------PWHVKADHGDE-LYLIFGSFFWGLKFSFTAEEK 483

  Fly   498 RLSRPDQSMAHRMVELWTNFVISGNPLGSARVGYWPPMTTLYGPYMRIDDTMTIG 552
            .|||       :|::.|.||...||| .|..:.|| |.:.....|:::|...::|
Mouse   484 LLSR-------KMMKYWANFARYGNP-NSEDLPYW-PASNQDDLYLQLDIHPSVG 529

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9287	NP_609244.1	COesterase	31..558	CDD:278561	153/555 (28%)
Ces2f	NP_001073334.2	COesterase	32..540	CDD:395084	153/553 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832771
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740