DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9287 and LOC688542

DIOPT Version :9

Sequence 1:	NP_609244.1	Gene:	CG9287 / 34194	FlyBaseID:	FBgn0032057	Length:	625	Species:	Drosophila melanogaster
Sequence 2:	XP_038954018.1	Gene:	LOC688542 / 688542	RGDID:	1587637	Length:	559	Species:	Rattus norvegicus

Alignment Length:	574	Identity:	158/574 - (27%)
Similarity:	246/574 - (42%)	Gaps:	96/574 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LLLVLQSVVESRVRGRQYDEEKDTIVELPTLGSIQGKILETAWTKREVLQFVDVRYAEPPTGLHR 75
            |||||      .|||    ::..:.:.....|.::|.::....|..:|..|:.:.:|:||.|..|
  Rat    18 LLLVL------HVRG----QDSASPIRNTHTGQVRGSLVHVKDTDIDVHTFLGIPFAKPPVGPLR 72

  Fly    76 FKAPRPIEPWEDVMDATAEKIGC---PSVVSMDSLRRLDDVLD----VEDCLTMTITTP---NVT 130
            |..|...|||..|.|||:....|   .:::..:.::.:..:|.    .||||.:.|..|   :..
  Rat    73 FAPPEAPEPWSGVRDATSHPAMCLQNDNMMGSEDMKIMKLILPPISMSEDCLYLNIYAPTHAHEG 137

  Fly   131 SRLPVLVYIHGEYL-------YEGSNSEAPPDYLLEKDVVLVTPQYRLGPFGFLSTKTDEIPGNA 188
            |.|||:|:|||..|       |:||...|      .:|||:||.|||||..||.||..:...||.
  Rat   138 SNLPVMVWIHGGALTVGMASMYDGSMLAA------TEDVVVVTIQYRLGVLGFFSTGDEHARGNW 196

  Fly   189 GFLDIFLALQFVKHFIKYFGGDPSRVTVAGQVGGAAIAHLLTLSPVVQRGLFHQVIYHSGSAIMP 253
            |:||...||::|:..|.:|||:|:|||:.|:..|........:||:.| ||||..|..||..::|
  Rat   197 GYLDQVAALRWVQQNIAHFGGNPNRVTIFGESAGGTSVSSHVVSPMSQ-GLFHGAIMESGVVVLP 260

  Fly   254 IFLEEDPRKHAQEIAKKADCKMVTVRDLNTCLMELTALELLTAFMEHALEKSDLGIGHTGGIQFT 318
            ..:........:.:|..:.|..|....|..||...:..|:|.......:            |...
  Rat   261 DLISRSSEMVYRIVANLSGCAAVDSETLMQCLRGKSEAEILDINKVFKI------------IPAV 313

  Fly   319 IGGPSGVLPKHPYDLMLETNF-SYPAMGGCPKNAGSRVLNEIVDNDFEGKIPDDEYNTYNYIDHV 382
            :.|.  .|||||.:|:...|| ..|::.|             ::||..|.|....:::...|:.:
  Rat   314 VDGE--FLPKHPQELLASANFHRVPSIIG-------------INNDEYGWILPMIFDSAQKIEEI 363

  Fly   383 IRQTVGTDKTMLLTSFVTHDFFNRNLMENGTFDTLIPRLI-----DVAGTLNHKLPVLLALNMNN 442
            .|:|:.|.........:........|||....||..|:.:     ::.|.....:|.|...:...
  Rat   364 TRKTLPTVLKSTALKMMLPPECGDLLMEEYMGDTEDPKTLQAQFREMMGDFMFVIPALQVAHFQR 428

  Fly   443 KHNPDNTFLYSFDYAGEFNRYKEMDEETNLQSPFKAGVSLTDEAL----YL-----FPYPEHVTR 498
            .|.|  .:.|.|.:...|  :|::       .|........||..    ||     ||:.|....
  Rat   429 SHAP--VYFYEFQHRSSF--FKDV-------KPPHVKADHGDEVFLVFGYLVGDIKFPHTEEEEL 482

  Fly   499 LSRPDQSMAHRMVELWTNFVISGNPLGSARVGYWPPMTTLYGPYMRIDDTMTIG 552
            |||       ::::.|.||...||| .|..:.:||.|.. ...|:::|...::|
  Rat   483 LSR-------KIMKYWANFARHGNP-NSEGLPHWPVMDH-DDQYLQLDIQPSVG 527

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9287	NP_609244.1	COesterase	31..558	CDD:278561	150/554 (27%)
LOC688542	XP_038954018.1	COesterase	30..538	CDD:395084	150/552 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910