Protein Alignment CG9287 and NLGN4X

DIOPT Version :10

• Sequence 1: NP_609244.1
• Gene: CG9287 / 34194
• FlyBaseID: FBgn0032057
• Length: 625
• Species: Drosophila melanogaster
• Sequence 2: XP_005274621.1
• Gene: NLGN4X / 57502
• HGNCID: 14287
• Length: 836
• Species: Homo sapiens
• Alignment Length: 584
• Identity: 160/584 - (27%)
• Similarity: 248/584 - (42%)
• Gaps: 116/584 - (19%)

  Fly     3 LLWWQIVSLLLVLQSVVESRVRGRQYDEEKDTIVELPTLGSIQGKI--LETAWTKREVL----QF 61
            |||   ::.|.:..::::|:.   ||          |.:.:..|||  |.|. ...|:|    |:
Human    26 LLW---LTALAIKFTLIDSQA---QY----------PVVNTNYGKIRGLRTP-LPNEILGPVEQY 73

  Fly    62 VDVRYAEPPTGLHRFKAPRPIEPWEDVMDATAEKIGCPSVVSMDSLRRLDDVLDV---------- 116
            :.|.||.||||..||:.|.|...|..:.:.|.....||.  .:|....|.|:|.:
Human    74 LGVPYASPPTGERRFQPPEPPSSWTGIRNTTQFAAVCPQ--HLDERSLLHDMLPIWFTANLDTLM 136

  Fly   117 -------EDCLTMTITTP------------NVT--------------SRLPVLVYIHGEYLYEGS 148
                   ||||.:.|..|            ::|              |:.||:|||||....||:
Human   137 TYVQDQNEDCLYLNIYVPTEDGANTKKNADDITSNDRGEDEDIHDQNSKKPVMVYIHGGSYMEGT 201

  Fly   149 NSEAPPDYLLE-KDVVLVTPQYRLGPFGFLSTKTDEIPGNAGFLDIFLALQFVKHFIKYFGGDPS 212
            .:......|.. .:|:::|..||||..|||||......||.|.||...||::::..:..|||||.
Human   202 GNMIDGSILASYGNVIVITINYRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPK 266

  Fly   213 RVTVAGQVGGAAIAHLLTLSPVVQRGLFHQVIYHSGSAIMPIFLEEDPRKHAQEIAKKADCKMVT 277
            |||:.|...||:...|||||. ...|||.:.|..||:|:....:...|.|:.:.:|.|..|.|:.
Human   267 RVTIFGSGAGASCVSLLTLSH-YSEGLFQKAIIQSGTALSSWAVNYQPAKYTRILADKVGCNMLD 330

  Fly   278 VRDLNTCLMELTALELLTAFMEHALEKSDLGIGHTGGIQFTIGGP---SGVLPKHPYDLMLETNF 339
            ..|:..||......||:...:..|          |..|.|   ||   ..|:|..|..||.:..|
Human   331 TTDMVECLRNKNYKELIQQTITPA----------TYHIAF---GPVIDGDVIPDDPQILMEQGEF 382

  Fly   340 -SYPAMGGCPKNAGSRVLNEIVDNDFEGKIPDD-EYNTYNYIDHVIRQTVGTDKTMLLTSFVTHD 402
             :|..|.|..:..|.:.::.||||: :|..|:| :::..|::|::.....|.|.......|:..|
Human   383 LNYDIMLGVNQGEGLKFVDGIVDNE-DGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETIKFMYTD 446

  Fly   403 FFNRNLMENGTFDTLIPRLIDVAGTLNHK--LPVLLALNMNNKHNPDNTFLYSFDYAGEFNRYKE 465
            :.::...|... .||:....|      |:  .|.:...:::.::. ..|:.|:|        |..
Human   447 WADKENPETRR-KTLVALFTD------HQWVAPAVATADLHAQYG-SPTYFYAF--------YHH 495

  Fly   466 MDEETNLQSPFKAGVSLTDEALYLFPYPE------HVTRLSRPDQSMAHRMVELWTNFVISGNP 523
            ...|   ..|..|..:..||..|:|..|.      .....|:.|..::..::..||||..:|:|
Human   496 CQSE---MKPSWADSAHGDEVPYVFGIPMIGPTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDP 556

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9287	NP_609244.1	COesterase	33..558	CDD:395084	153/554 (28%)
NLGN4X	XP_005274621.1	COesterase	44..610	CDD:395084	155/560 (28%)