DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9287 and tg

DIOPT Version :9

Sequence 1:	NP_609244.1	Gene:	CG9287 / 34194	FlyBaseID:	FBgn0032057	Length:	625	Species:	Drosophila melanogaster
Sequence 2:	NP_001316794.1	Gene:	tg / 567631	ZFINID:	ZDB-GENE-030519-1	Length:	2733	Species:	Danio rerio

Alignment Length:	579	Identity:	152/579 - (26%)
Similarity:	233/579 - (40%)	Gaps:	127/579 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 TIVELPTLGSIQG----KILETAWTKREVLQFVDVRYAEPPTGLHRFKAPRPIEPWEDVMDATAE 94
            |.|.:|..|::.|    |.:..:.:|| |..|:.|.||.||.|..||..|:|.: |....:||..
Zfish  2164 TSVSIPDHGTLLGESEVKPITGSDSKR-VTYFLGVPYARPPIGDLRFSPPQPAD-WTGTWNATFF 2226

  Fly    95 KIGC--PSVVSMDSLRRLDDVLDVEDCLTMTI-TTPNVTSRLPVLVYIH--GEYLYEGSNSEAPP 154
            :..|  |.        .|.|....||||.:.: ...:|....||||:.|  |..|.:||
Zfish  2227 RSSCLQPG--------DLTDSSSSEDCLYLNVFVASSVAKNAPVLVFFHNSGSDLLDGS------ 2277

  Fly   155 DYLLE-KDVVLVTPQYRLGPFGFLSTKTDEIPGNAGFLDIFLALQFVKHFIKYFGGDPSRVTVAG 218
             ||.. .::::||..:|:..|||||..:..:|||.|..|...||.:|:..|..|||||::|||..
Zfish  2278 -YLAAVGNIIVVTASFRMAAFGFLSAGSSALPGNYGLQDQAAALGWVQKNIALFGGDPTKVTVGA 2341

  Fly   219 QVGGAAIAHLLTLSPVVQRGLFHQVIYHSGSAIMPIFLEEDPRKHAQ--EIAKKADCKMVTVRDL 281
            :..||.||.|...||... .||.:.:...||...|..:....:..||  .:|::.||:......|
Zfish  2342 ERNGADIASLHLTSPSAS-SLFSRALLMGGSVFSPAVVMSSSKAQAQTSSLARELDCQAADPSQL 2405

  Fly   282 NTCLMELTALELLTAFMEHALEKSDLGIGHTGGIQF---TIGG------PSGVLPK---HPYDLM 334
            ..||....|..:      :|.:...|.:  :|.:|.   .:.|      ||..|..   |..:::
Zfish  2406 LDCLRSKPAHSI------NAAQTKLLAV--SGPLQAWSPVVDGNVVREMPSVALQSGRFHKAEIL 2462

  Fly   335 LETNFSYPAMGGCPKNAGSRVLNEIVDNDFEGKIPDDEYNTYNYIDHVIRQTVGTDKTMLLTSFV 399
            |.::|....:        ||..|.......:|: .|.:...|..:.:.:.   |.|....:....
Zfish  2463 LGSSFEDGLI--------SRAKNIKNFEQLQGR-ADSKTAFYAALSNSLG---GDDANAFVKEAA 2515

  Fly   400 T-------------HDFFNRNLMENGTFDT-LIPRLIDVA--GTLNHKLPVLLALNMNNKHNPDN 448
            |             ::.|:|.| ||.|.|. :|...:|:|  ...|.:..|.:      .|.|:|
Zfish  2516 TWFYSLQHSPTPSGYNVFSRAL-ENATRDLFIICPTVDMAEFWAANTQTGVYM------YHLPEN 2573

  Fly   449 TFLYSFDYAGEFNRYKEMDEETNLQSPFKAGVSLTDEALYLFPYPEHVTRLSRPDQSMAHRMVEL 513
            .            .|..:|....:...:..||.|..|...||.|.|....|         :::..
Zfish  2574 A------------AYNSVDLSVPMDVQYLFGVPLAAEQRDLFSYKEKTFTL---------QIMNY 2617

  Fly   514 WTNFVISGN---PLGSARVGY------WPPMTTLYGPYMRIDDTMTIGGNYFTEFSATL 563
            ..||:.|||   ||.::|..:      ||.    :.|:        :||..:.|.|:||
Zfish  2618 MANFIKSGNPNLPLAASRTSFGKFLPPWPQ----FMPH--------VGGRAYKELSSTL 2664

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9287	NP_609244.1	COesterase	31..558	CDD:278561	148/572 (26%)
tg	NP_001316794.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575640
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.930