Protein Alignment CG9287 and ACHE

DIOPT Version :9

• Sequence 1: NP_609244.1
• Gene: CG9287 / 34194
• FlyBaseID: FBgn0032057
• Length: 625
• Species: Drosophila melanogaster
• Sequence 2: NP_001354847.1
• Gene: ACHE / 43
• HGNCID: 108
• Length: 681
• Species: Homo sapiens
• Alignment Length: 611
• Identity: 162/611 - (26%)
• Similarity: 244/611 - (39%)
• Gaps: 157/611 - (25%)

  Fly    11 LLLVLQSVVESRVRGRQYDEEKDTIVELPTLGSIQGKILETAWTKREVLQFVDVRYAEPPTGLHR 75
            |||:|..::...| |.:..|:.:.:|.:.. |.::|..|:|  ....|..|:.:.:||||.|..|
Human    84 LLLLLLWLLGGGV-GAEGREDAELLVTVRG-GRLRGIRLKT--PGGPVSAFLGIPFAEPPMGPRR 144

  Fly    76 FKAPRPIEPWEDVMDATAEKIGCPSVVSMDSL-------------RRLDDVLDVEDCLTMTITT- 126
            |..|.|.:||..|:|||..:..|...|  |:|             |.|.     ||||.:.:.|
Human   145 FLPPEPKQPWSGVVDATTFQSVCYQYV--DTLYPGFEGTEMWNPNRELS-----EDCLYLNVWTP 202

  Fly   127 -PNVTSRLPVLVYIHGEYLYEGSNSEAPPD--YLLEKD-VVLVTPQYRLGPFGFLSTK-TDEIPG 186
             |..||..||||:|:|...|.|::|....|  :|::.: .|||:..||:|.||||:.. :.|.||
Human   203 YPRPTSPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPG 267

  Fly   187 NAGFLDIFLALQFVKHFIKYFGGDPSRVTVAGQVGGAAIAHLLTLSPVVQRGLFHQVIYHSGSAI 251
            |.|.||..||||:|:..:..|||||:.||:.|:..|||...:..||| ..|||||:.:..||:..
Human   268 NVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLSP-PSRGLFHRAVLQSGAPN 331

  Fly   252 MP---IFLEEDPRKHAQEIAKKADCKMVTVRDLNTCLMELTALELLTAFMEHALEKSDLGIGHTG 313
            .|   :.:.| .|:.|.::|....|..                                  |.||
Human   332 GPWATVGMGE-ARRRATQLAHLVGCPP----------------------------------GGTG 361

  Fly   314 GIQFTIGG-----PSGVLPKHPYDLMLETN---FSYPAMGGCPKNAGSRVLNEIVDNDFEGKIPD 370
            |....:..     |:.||..|.:.::.:.:   ||:.               .:||.||....|:
Human   362 GNDTELVACLRTRPAQVLVNHEWHVLPQESVFRFSFV---------------PVVDGDFLSDTPE 411

  Fly   371 DEYNTYNYIDHVIRQTVGT--DKTMLLTSFVTHDFF--NRNLMENGTF----------------- 414
            ...|..::  |.::..||.  |:......:....|.  |.:|:....|
Human   412 ALINAGDF--HGLQVLVGVVKDEGSYFLVYGAPGFSKDNESLISRAEFLAGVRVGVPQVSDLAAE 474

  Fly   415 -------DTLIPR--------LIDVAGTLNHKLPV------LLALNMNNKHNPDNTFLYSFDYAG 458
                   |.|.|.        |.||.|..|...||      |.|...       ..:.|.|::
Human   475 AVVLHYTDWLHPEDPARLREALSDVVGDHNVVCPVAQLAGRLAAQGA-------RVYAYVFEH-- 530

  Fly   459 EFNRYKEMDEETNLQSPFKAGVSLTDEALYLFPYPEHVTR-LSRPDQSMAHRMVELWTNFVISGN 522
                     ..:.|..|...||....|..::|..|...:| .:..::..|.|::..|.||..:|:
Human   531 ---------RASTLSWPLWMGVPHGYEIEFIFGIPLDPSRNYTAEEKIFAQRLMRYWANFARTGD 586

  Fly   523 P--LGSARVGYWPPMTTLYGPYMRID 546
            |  ....:...|||.|.....|:.:|
Human   587 PNEPRDPKAPQWPPYTAGAQQYVSLD 612

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9287	NP_609244.1	COesterase	31..558	CDD:278561	155/591 (26%)
ACHE	NP_001354847.1	COesterase	104..630	CDD:395084	155/590 (26%)
		AChE_tetra	645..678	CDD:400834

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165142770
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.840