DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9287 and alpha-Est10

DIOPT Version :9

Sequence 1:	NP_609244.1	Gene:	CG9287 / 34194	FlyBaseID:	FBgn0032057	Length:	625	Species:	Drosophila melanogaster
Sequence 2:	NP_001246962.1	Gene:	alpha-Est10 / 40896	FlyBaseID:	FBgn0015569	Length:	581	Species:	Drosophila melanogaster

Alignment Length:	545	Identity:	141/545 - (25%)
Similarity:	243/545 - (44%)	Gaps:	81/545 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 LQSVVESRVRGRQYDEEKDTIVELPTLGSIQGKILETAWTKREVLQFVDVRYAEPPTGLHRFKAP 79
            :|.|:..:...|:......::::..: |.::|....|.| ......|..:.:|:||.|..|||||
  Fly    30 IQQVISFKYEQRKLSTAIYSVIKTKS-GPVRGVKRNTIW-GGSYFSFEKIPFAKPPVGDLRFKAP 92

  Fly    80 RPIEPWEDVMDATAEKIGCPSVVSMDSLRRLDDVLDVEDCLTMTITTPNV-TSRL-PVLVYIH-- 140
            ..:|||:..:|.|:     |:...:.:..........||||.:.:...:: ..:| ||:|:|:
  Fly    93 EAVEPWDQELDCTS-----PADKPLQTHMFFRKYAGSEDCLYLNVYVKDLQPDKLRPVMVWIYGG 152

  Fly   141 GEYLYEGSNSEAPPDYLLEKDVVLVTPQYRLGPFGFLSTKTDE--IPGNAGFLDIFLALQFVKHF 203
            |..:.|.|.....||:.:.||||:||..||||..||||....:  :|||||..|..:||::|:..
  Fly   153 GYQVGEASRDMYSPDFFMSKDVVIVTVAYRLGALGFLSLDDPQLNVPGNAGLKDQIMALRWVQQN 217

  Fly   204 IKYFGGDPSRVTVAGQVGGAAIAHLLTLSPVVQRGLFHQVIYHSGSAIMPIFLEEDPRKH----- 263
            |:.||||.:.:|:.|:..|.|..|.|.|||..: ||.|:.|..|||.:.|  ..:.||.:
  Fly   218 IEAFGGDSNNITLFGESAGGASTHFLALSPQTE-GLIHKAIVMSGSVLCP--WTQPPRNNWAYRL 279

  Fly   264 AQEIAKKADCKMVTVRDLNTCLMELTALELL--TAFMEHALEKSDLGIGHTGGIQFTIGGPSGVL 326
            ||::....|.|...:.:.   |..::..|::  ||.:....||....:...|.:.........|:
  Fly   280 AQKLGYTGDNKDKAIFEF---LRSMSGGEIVKATATVLSNDEKHHRILFAFGPVVEPYTTEHTVV 341

  Fly   327 PKHPYDLMLETNFSY--PAMGGCPKNAG-------SR---VLNEIVDNDFEGKIPDD-EYNTYNY 378
            .|.|::|| :.::|:  |.|.|.....|       ||   .|:|:  .:.:..:|.| ..|
  Fly   342 AKQPHELM-QNSWSHRIPMMFGGTSFEGLLFYPEVSRRPATLDEV--GNCKNLLPSDLGLN---- 399

  Fly   379 IDHVIRQTVGTDKTMLLTSFVTHDFFNR-NLMENGTFDTLIPRLIDVAGTLNHKLPVLLALNMNN 442
            :|..:|:..|   ..|..::...:..|: |:|          :.:::........|:..|.....
  Fly   400 LDPKLRENYG---LQLKKAYFGDEPCNQANMM----------KFLELCSYREFWHPIYRAALNRV 451

  Fly   443 KHNPDNTFLYSFDYAGEFNRYKEMDEETNLQSPFK--------AGVSLTDEALYLF-PYPEHVTR 498
            :.:...|:||.||:            ::.|.:..:        .||...|:..|:| ....|.:.
  Fly   452 RQSSAPTYLYRFDH------------DSKLCNAIRIVLCGHQMRGVCHGDDLCYIFHSMLSHQSA 504

  Fly   499 LSRPDQSMAHRMVELWTNFVISGNP 523
            ...|:..:...||::||:|...|:|
  Fly   505 PDSPEHKVITGMVDVWTSFAAHGDP 529

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9287	NP_609244.1	COesterase	31..558	CDD:278561	138/529 (26%)
alpha-Est10	NP_001246962.1	COesterase	49..542	CDD:278561	138/526 (26%)
alpha-Est10	NP_001246962.1	Aes	<132..>279	CDD:223730	57/149 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45467465
Domainoid	1	1.000	98	1.000	Domainoid score	I1867
eggNOG	1	0.900	-	-		E2759_KOG1516
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR43142
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.840