DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9287 and Est-Q

DIOPT Version :9

Sequence 1:	NP_609244.1	Gene:	CG9287 / 34194	FlyBaseID:	FBgn0032057	Length:	625	Species:	Drosophila melanogaster
Sequence 2:	NP_649321.1	Gene:	Est-Q / 40381	FlyBaseID:	FBgn0037090	Length:	559	Species:	Drosophila melanogaster

Alignment Length:	564	Identity:	179/564 - (31%)
Similarity:	279/564 - (49%)	Gaps:	52/564 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 RGRQYDEEKDTIVELPT-LGSIQGKILETAWTKREVLQFVDVRYAEPPTGLHRFKAPRPIEPWED 87
            :|....|.....|||.. .|::.|....||||.|..:||..:.:||||....||:.|....||..
  Fly    32 QGADASETATVTVELYNGQGTVLGNYAYTAWTDRAFMQFRGIPFAEPPIEELRFRPPVARSPWTG 96

  Fly    88 VMDATAEKIGCPSVVSMDSLRRLDDVLDVEDCLTMTITTPNVTSRLPVLVYIHGEYLYEGSNSEA 152
            .::|......||.:.::||  ::.|. ::|||||:::.|.|:::..||:.||:|...|.||:.:.
  Fly    97 TLNALNFGQRCPVITNLDS--QMSDA-ELEDCLTLSVYTKNLSASQPVMFYIYGGGFYNGSSEDH 158

  Fly   153 PPDYLLEKDVVLVTPQYRLGPFGFLSTKTDEIPGNAGFLDIFLALQFVKHFIKYFGGDPSRVTVA 217
            ||:||||||||||.||||:|..|:|||.|:|:||||...||.:||.:|:..|..|||||.:||:.
  Fly   159 PPNYLLEKDVVLVVPQYRVGALGWLSTYTEELPGNAPIADILMALDWVQMHISSFGGDPQKVTIF 223

  Fly   218 GQVGGAAIAHLLTLSPVVQRGLFHQVIYHSGSAIMPIFLEEDPRKHAQEIAKKADCKMVTVRD-L 281
            ||..||.:|..|.|||.....:|.:.|..|||......:.:||:..::.|..:..|......| |
  Fly   224 GQSAGAGVASSLLLSPKTGDNMFKRAIVQSGSIFASWAINKDPKAQSRRICIQLGCSGCEQHDQL 288

  Fly   282 NTCLMELTALELLTAFMEHALEKSDLGIGHTGGIQFT--IGGPSGVLPKHPYDLMLETNFSYPAM 344
            ..|:.:...:::|.|               |....|:  :|...|:||:.|.:|:.......|.:
  Fly   289 VKCIQKAKVIDILKA---------------TASESFSPIVGDLHGILPQQPSELVKSYRRQIPIL 338

  Fly   345 GGCPKNAGSRVLNEIVDNDFEGKIPDDEYNTYNYIDHVIRQ-TVGTDKTMLLTSFVTHDFFNRNL 408
            .|..::.||.||....| ....|:.       |.....:|| :.|.:..:..||.:|.:..||.|
  Fly   339 TGFTQHDGSFVLASYYD-ALAAKVA-------NVSSLSVRQFSQGINDLVNDTSGLTDNILNRLL 395

  Fly   409 -----MENGTFDTLIPRLIDVAGTLNHKLPVL-LALNMNNKHNPDNTFLYSFDYAGEFNRYKEMD 467
                 :.:......:....|:...:..|.||: ||..|..:......::|||:|.|.:.|:..
  Fly   396 FKPQALNSHDHSAAVSSYFDLTTNIFMKSPVITLATKMYTQQRSTPVYVYSFEYEGTYTRFGY-- 458

  Fly   468 EETNLQSPFKAGVSLTDEALYLF-PYPEHVTRLSRPDQSMAHRMVELWTNFVISGNPLGSARVGY 531
            |..|...||..||..:::.:||| .:|     |...|..|:.:||::||:|.|.|.|...:
  Fly   459 EFGNSHYPFNGGVHHSNDNIYLFATHP-----LEGQDTQMSQKMVDVWTSFAIEGVPRNLS---- 514

  Fly   532 WPPMTTLYGPYMRIDDTMTIGGNYFTEFSATLSDEEQGHSLIRE 575
              |:::..|||.:::..:|.|.:.....:|.:.|.:.|. |.||
  Fly   515 --PLSSASGPYNKLNLEVTKGDDLLDTLTAAIDDPDNGR-LQRE 555

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9287	NP_609244.1	COesterase	31..558	CDD:278561	171/538 (32%)
Est-Q	NP_649321.1	COesterase	39..544	CDD:278561	172/543 (32%)
Est-Q	NP_649321.1	Aes	<137..>240	CDD:223730	56/102 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	98	1.000	Domainoid score	I1867
eggNOG	1	0.900	-	-		E2759_KOG1516
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	99	1.000	Inparanoid score	I1664
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG25739
OrthoDB	1	1.010	-	-		D206516at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR43142
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.980