DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9287 and Est-P

DIOPT Version :9

Sequence 1:	NP_609244.1	Gene:	CG9287 / 34194	FlyBaseID:	FBgn0032057	Length:	625	Species:	Drosophila melanogaster
Sequence 2:	NP_788501.1	Gene:	Est-P / 39393	FlyBaseID:	FBgn0000594	Length:	544	Species:	Drosophila melanogaster

Alignment Length:	573	Identity:	136/573 - (23%)
Similarity:	232/573 - (40%)	Gaps:	115/573 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 QIVSLLLVLQSVVESRVRGRQYDEEKDTIVELPTLGSIQGKILETAWTKREVLQFVDVRYAEPPT 71
            :::.|.|:..:.:||        |....|||: |.|.|:||      .......:..:..||.||
  Fly     6 RLLCLTLLWIAALES--------EADPLIVEI-TNGKIRGK------DNGLYYSYESIPNAEHPT 55

  Fly    72 GLHRFKAPRPI-EPWEDVMDATAEKIGCPSVVSMDSLRRLDDVLDVEDCLTMTITTPNVTSR--L 133
            |..||:||:|. ..|.||.:||...:.|  :.....:...:.::..|||||::|..|...:|  .
  Fly    56 GALRFEAPQPYSHHWTDVFNATQSPVEC--MQWNQFINENNKLMGDEDCLTVSIYKPKKPNRSSF 118

  Fly   134 PVLVYIHGEYLYEGSNSEAPPDYLLEKDVVLVTP-QYRLGPFGFLSTKTDEIPGNAGFLDIFLAL 197
            ||:|.:||.....||.|....|.::.:..:||.. .:.|||.||.||....:|||.|..|..|||
  Fly   119 PVVVLLHGGAFMFGSGSIYGHDSIMREGTLLVVKISFGLGPLGFASTGDRHLPGNYGLKDQRLAL 183

  Fly   198 QFVKHFIKYFGGDPSRVTVAGQVGGAAIAHLLTLSPVVQRGLFHQVIYH--------SGSAIMPI 254
            |::|..|.:|||.|..:.:.|...|.|.|||         .|.|:...|        ||:|:.|.
  Fly   184 QWIKKNIAHFGGMPDNIVLIGHSAGGASAHL---------QLLHEDFKHLAKGAISVSGNALDPW 239

  Fly   255 FLEEDPRKHAQEIAKKADCKMVTV-RDLNTCLMELTALELLTAFMEHALEKSDLGIGHTGGIQFT 318
            .:::..|:.|.|:.:...|....| .:|..||....|.::::|.      :|.|...:   :.|:
  Fly   240 VIQQGGRRRAFELGRIVGCGHTNVSAELKDCLKSKPASDIVSAV------RSFLVFSY---VPFS 295

  Fly   319 IGGPSGVLPKHPYDLMLETNFSYPAMGGCPKNAGSRVLNE----IVDNDFEGKIP--------DD 371
            ..||           ::|           |.:|....|.|    ::.:....::|        |.
  Fly   296 AFGP-----------VVE-----------PSDAPDAFLTEDPRAVIKSGKFAQVPWAVTYTTEDG 338

  Fly   372 EYNTYNYIDHVIRQTVGTDKTMLLT----SFVTHDFFNRNL------MENGTFDT----LIPRLI 422
            .||....::.  .:..|.....||.    .:..:..|.|:.      |::.:||.    |..|..
  Fly   339 GYNAAQLLER--NKLTGESWIDLLNDRWFDWAPYLLFYRDAKKTIKDMDDLSFDLRQQYLADRRF 401

  Fly   423 DVAGTLN---------HKLPVLLALNMNNKHNPDNTFLYSFDYAGEFNRYKEMDEETNLQSPFKA 478
            .|....|         .|..|..|::::.|:.....:.:.:|...:....:.:...|::.    .
  Fly   402 SVESYWNVQRMFTDVLFKNSVPSAIDLHRKYGKSPVYSFVYDNPTDSGVGQLLSNRTDVH----F 462

  Fly   479 GVSLTDEALYLFPYPEHVTRLSRPDQS-MAHRMVELWTNFVISGNPLGSARVG 530
            |....|:...:|....:.|.: |||:. ::.:.:.:..:|.:  |..|:...|
  Fly   463 GTVHGDDFFLIFNTAAYRTGI-RPDEEVISKKFIGMLEDFAL--NDKGTLTFG 512

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9287	NP_609244.1	COesterase	31..558	CDD:278561	131/549 (24%)
Est-P	NP_788501.1	Esterase_lipase	26..537	CDD:238191	131/545 (24%)
Est-P	NP_788501.1	Aes	<107..>240	CDD:223730	49/141 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440375
Domainoid	1	1.000	98	1.000	Domainoid score	I1867
eggNOG	1	0.900	-	-		E2759_KOG1516
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	99	1.000	Inparanoid score	I1664
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.790