DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9287 and CG12869

DIOPT Version :9

Sequence 1:	NP_609244.1	Gene:	CG9287 / 34194	FlyBaseID:	FBgn0032057	Length:	625	Species:	Drosophila melanogaster
Sequence 2:	NP_001369085.1	Gene:	CG12869 / 36616	FlyBaseID:	FBgn0033943	Length:	839	Species:	Drosophila melanogaster

Alignment Length:	567	Identity:	131/567 - (23%)
Similarity:	233/567 - (41%)	Gaps:	92/567 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 QIVSLLLVLQSVVESRVRGRQYDEEKDTIVELPTLGSIQGKILETAWTKREVLQFVDVRYAEPPT 71
            ||:.||.:|       :....|...:.|.::|.. |.:.|..:....|:..|..|:.:.||:.|.
  Fly     9 QILRLLPIL-------IHLSPYISAQQTHIKLEQ-GDLIGLKVFPDGTRGAVYAFLGIPYAQAPI 65

  Fly    72 GLHRFKAPRPIEPWEDVMDATAEKIGCPSVV-------SMDSLRRLDDVLDVEDCLTMTITTPNV 129
            ...||...:|...:...:.||..:..||.:.       |..|:.|  .|...||||.:.|.||..
  Fly    66 NELRFAPAKPSSSFNRTLQATTMQPLCPQLANTIYDESSDGSMPR--SVSTDEDCLYLNIWTPES 128

  Fly   130 TSR---LPVLVYIHG-EYLYEGSNSEAPPDYLLEKDVVLVTPQYRLGPFGFLS--TKTDEIPGNA 188
            ..|   ||::|.:.| |:.|:...:......|..:.:|:|:.|||...:|:||  .:...:|||.
  Fly   129 GMRYGKLPIVVIVTGEEFAYDWPRNRINGLDLAGEGIVVVSVQYRNNIYGWLSLGEQHRNVPGNY 193

  Fly   189 GFLDIFLALQFVKHFIKYFGGDPSRVTVAGQ-VGGAAIAHLLTLSPVVQRGLFHQVIYHSGSAIM 252
            |..|:.:||::::.....|||:|..:|:.|. .|||.:|.:.||....|   ..|::..|...||
  Fly   194 GLSDVQMALRWIRRNADAFGGNPDHITLLGHGSGGAPLALVATLEDSSQ---VKQLVLMSPGPIM 255

  Fly   253 PIFLEEDPR---KHAQEIAKKADCKMVTV--RDLNTCLMELTALELLTAF---MEHALEKSDLGI 309
            ....:...:   :..|.:.:|..|:....  |.|..||...:..:||.|:   ..|....|.||:
  Fly   256 RALGQNHQKWIVETGQVLVQKLGCQFEEAQRRQLMGCLRRKSREDLLRAYESVYNHGNGSSQLGV 320

  Fly   310 GHTGGIQFTIGGPSGVLPKH-PYDLMLETNFSYPAMGGCPKNAGSRVLNEIVDNDFEGKIPDDEY 373
                           :||:. |.:..|......|.:.|...|.|:.:.:..:|...||::...:|
  Fly   321 ---------------ILPEGLPLEQRLRNKTLPPVLLGITSNEGAFLQDYWLDVAREGQVALHKY 370

  Fly   374 NTYNYIDHVIR--QTVGTDKTMLLTSFVTHDFFN-------------RNLMENGTFDTLIPRLID 423
            ..:..:.:|:|  ::||.:.:..|.: :...:||             :.|:....::....|:::
  Fly   371 INHTLLPNVMRALESVGEESSTQLAA-IRWRYFNGKGEGVSHLLAGMQRLLSESLYELPYSRILE 434

  Fly   424 VA-GTLNHKLPVLLALNMNNKHNPDNTFLYSFDYAGEFNRYKEMDEETNLQSPFKAGVSLTDEAL 487
            :. ||.::      |...::.|        |.|..|..|.:......::|  |...|.||..:..
  Fly   435 LLNGTTSY------AYVFDHSH--------SMDMRGRRNLFGGASHSSDL--PLLLGPSLFQQIA 483

  Fly   488 YLFPYPEHVTRLSRPDQSMAHRMVELWTNFVISGNPLGSARVGYWPP 534
            .        .|.|..::.:..::...:.||:.:|||........|.|
  Fly   484 R--------RRFSGEEEQLCRKIRGAFANFIKNGNPTPGRIYDGWLP 522

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9287	NP_609244.1	COesterase	31..558	CDD:278561	125/543 (23%)
CG12869	NP_001369085.1	COesterase	27..541	CDD:395084	125/542 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810