DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9287 and CG5397

DIOPT Version :9

Sequence 1:	NP_609244.1	Gene:	CG9287 / 34194	FlyBaseID:	FBgn0032057	Length:	625	Species:	Drosophila melanogaster
Sequence 2:	NP_001259865.1	Gene:	CG5397 / 33313	FlyBaseID:	FBgn0031327	Length:	665	Species:	Drosophila melanogaster

Alignment Length:	645	Identity:	164/645 - (25%)
Similarity:	275/645 - (42%)	Gaps:	132/645 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 SLLLVLQSVV---------ESRVR------GRQ-----YDE--------EKDTIVE---LPTLGS 43
            :|||:|.|||         ::.||      |:|     .|:        ::|..||   .|:.|
  Fly     9 TLLLLLLSVVILASCKSGGDAHVRVKRIVGGKQSKAPPVDDPVIFARLFDRDARVEGFRNPSTG- 72

  Fly    44 IQGKILETAWTKREVLQFVDVRYAEPPTGLHRFKAPRPIEPWEDVM-DATAEKIGCPSVVSMDSL 107
                          :..|:.:.|||||.|..|:.  ||:  ::.:. |..|.|.|.|.:......
  Fly    73 --------------IYSFLGMHYAEPPVGPLRYS--RPV--YKRLAGDFNATKHGPPCIQPHPQF 119

  Fly   108 RRLDDVLDVEDCLTMTITTPNV---TSRLPVLVYIH-GEYLYEGSNSEAPPDYLLEKDVVLVTPQ 168
            .:  .::..||||.:.:.||.:   |:.|||.|:|| |.|.| ||.::.....:.::..::|.||
  Fly   120 PQ--RIIGDEDCLLLNVYTPQMPDETTGLPVFVWIHPGGYRY-GSAAQYDATPMAQRGAIVVAPQ 181

  Fly   169 YRLGPFGFLSTKTDEIPGNAGFLDIFLALQFVKHFIKYFGGDPSRVTVAGQVGGAAIAHLLTLSP 233
            ||||..|.:...|.:..||....|:..||::|..:|.||||:|.:|...|...|||.|..|::||
  Fly   182 YRLGSLGIMGDGTKQFDGNLAMFDLAAALRWVTDYISYFGGNPKQVQAIGHGSGAASAMYLSMSP 246

  Fly   234 VVQ-RGLFHQVIYHSGSAIMPIFLEEDPRKHAQEIAKKADCKMVTVRDLNTCLMELTALELLTAF 297
            ..: .|..|.|:..||:|:....::::|.:..||:||...|......::..||...:|.:::
  Fly   247 TSRSAGDVHGVVAMSGTALSQYAMDKEPVQSVQEVAKINGCPTGNELEIVNCLRSKSAEDII--- 308

  Fly   298 MEHALEKSD------------LGIGHTGGIQFTIGGP-------SGVLPK----HPYDLMLETNF 339
                  |:|            |..|.||.:.|.   |       ...||.    .|...:..:||
  Fly   309 ------KNDDKVQTERLAGRALVKGLTGNVGFQ---PHIESEDDGRALPSLIVGEPEQQLKSSNF 364

  Fly   340 S-YPAMGGCPKN-AGSRVLNEIVD------NDFEGKIPD--DEYNTYNYIDHVIRQTVGTDKTML 394
            | .|.:.|..|: ..:.|..|.::      ..|.|.:.|  ::..::..||.:..| :...:...
  Fly   365 SGIPLLTGVTKHETANSVTVETIEKVFGSAEQFLGSLSDSLNKLTSFLKIDKLTGQ-IAKPELPG 428

  Fly   395 LTSFVT---HDFFNRNLMENGTFDTLIPRLIDVAGTLNHKLPVLLALNMNNKHNPDNTFLYSFDY 456
            |||.:|   .|.:  .:.:....|.::.::::....:...||.:|...:.::..|  .|:|||:|
  Fly   429 LTSVLTPTLQDVW--KVPQALNVDQVLSKVVESTTDVLFNLPAVLTTQVWSRLAP--AFMYSFEY 489

  Fly   457 AG------EFNRYKEMDEETNLQSPFKAGVSLTDEALYLFP------YPEHVTRL-SRPDQSMAH 508
            .|      .|.:...:..||....|...|..  ||..|:|.      .|...||| |..|..:.:
  Fly   490 NGTKSKGINFLKGLPIVSETAHDKPETVGHG--DEIGYMFDANDIFGNPMEETRLTSAEDLKVRN 552

  Fly   509 RMVELWTNFVISGNPLGSARVGYWPPMTTLYGPYMRIDDTMTIGGNY-FTEFS---ATLS 564
            .:::|...|.......| .:...:..:|....|:::||..:....:: |.|.|   |:||
  Fly   553 NLIDLLVKFANKDKEEG-GKSSIFQSVTGKATPFIKIDTKLQTSNDFRFCELSVLGASLS 611

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9287	NP_609244.1	COesterase	31..558	CDD:278561	147/585 (25%)
CG5397	NP_001259865.1	COesterase	62..600	CDD:278561	145/579 (25%)
CG5397	NP_001259865.1	Aes	82..>261	CDD:223730	64/185 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	98	1.000	Domainoid score	I1867
eggNOG	1	0.900	-	-		E2759_KOG1516
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.810