DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9287 and cel.1

DIOPT Version :9

Sequence 1:	NP_609244.1	Gene:	CG9287 / 34194	FlyBaseID:	FBgn0032057	Length:	625	Species:	Drosophila melanogaster
Sequence 2:	NP_955901.2	Gene:	cel.1 / 322481	ZFINID:	ZDB-GENE-030131-1201	Length:	550	Species:	Danio rerio

Alignment Length:	572	Identity:	141/572 - (24%)
Similarity:	225/572 - (39%)	Gaps:	127/572 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 LGSIQGKILETAWTKREVLQ--------------FVDVRYAEPPTGLHRFKAPRPIEPWEDVMDA 91
            ||:.||..|....|:..::|              |..:.:|.||   .||:.|.....||.|:..
Zfish    14 LGTAQGASLGAVLTEGGMVQGKSRSVGLFRYMDTFKGIPFAAPP---KRFEKPVAHPGWEGVLKT 75

  Fly    92 TAEKIGCPSVVSMDSLRRLDDVLDVEDCLTMTITTP---NVTSRLPVLVYIHG------------ 141
            |..:..|   :.::.|  ..||:..||||.:.|..|   .|:|.|||:|:|:|
Zfish    76 TDYRKRC---LQLNLL--ATDVIGSEDCLYLNIWVPQGRTVSSNLPVMVFIYGGAFLLGGGQGAN 135

  Fly   142 ---EYLYEGSNSEAPPDYLLEKDVVLVTPQYRLGPFGFLSTKTDEIPGNAGFLDIFLALQFVKHF 203
               .|||:|   |...|   ..:|::||..||:|..||:||..|.||||.|..|...|:.:|...
Zfish   136 FLDNYLYDG---EEMAD---RGNVIVVTFNYRVGALGFMSTGDDGIPGNYGLWDQHAAISWVHRN 194

  Fly   204 IKYFGGDPSRVTVAGQVGGAAIAHLLTLSPVVQRGLFHQVIYHSGSAIMPIFLEEDPRKHAQEIA 268
            ||.|||:|..:|:.|:..|||..:...::| ..:|:..:.|..||.|:.|..:..:||:.|:|||
Zfish   195 IKAFGGNPDNITLFGESAGAASVNFQIITP-KNKGMIRRAISQSGVALCPWAISRNPRQFAEEIA 258

  Fly   269 KKADCKMVTVRDLNTCLMELTALELLTAFMEHALEKSDLGIGHTGGIQFTIGGPSGVLPKHPYDL 333
            .|..|.:.:  .:..||.......:..|.........|..|.|...:...|.|  ..:|..|
Zfish   259 TKVGCPIDS--GMADCLKRADPKAVTLAGKLKLTSSPDAPIVHNLYLSPVIDG--DFIPDEP--- 316

  Fly   334 MLETNFSYPAMGGCPKNAGSRVLNEIVDNDFEGKIPDDEYNTYNYID-----HVIRQTVGTDKTM 393
              ||.|...|                 |.|:...:.|.:.:.:..||     :.:..|...:...
Zfish   317 --ETLFGNAA-----------------DIDYIAGVNDMDAHIFATIDIPSINNALTTTPVEEVQA 362

  Fly   394 LLTS----------FVTHDFFNRNLMENGTFDTLIPRLIDVAGTLNHKLPVLLALNMNNKHNPDN 448
            |.|:          ..|...:..|..:....:.:...::::.......:|...||.::.    ||
Zfish   363 LATALSRDRGQDAGIATFQEYTVNWGDKPNKEKVKQTVVELETDYMFLVPTQAALYLHT----DN 423

  Fly   449 -----TFLYSFDYAGEFNRYKEMDEETNLQSPFKAGVSLTDEALYLFP---------YPEHVTRL 499
                 ||.|.|..:.....:           |...|....||..|:|.         :|.|
Zfish   424 AKSARTFSYLFTESSRIPVF-----------PLWMGADHADELQYVFGKPFATPLGYFPRH---- 473

  Fly   500 SRPDQSMAHRMVELWTNFVISGNP-LGSARVGY-WPPMTTLYGPYMRIDDTM 549
                :.::..|:..|:||..:|:| .|.::|.. ||..:.....|:.|::.|
Zfish   474 ----RDVSKYMIAYWSNFAQTGDPNKGESKVPVTWPEFSNPGHQYLDINNKM 521

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9287	NP_609244.1	COesterase	31..558	CDD:278561	141/572 (25%)
cel.1	NP_955901.2	COesterase	25..517	CDD:306613	134/555 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575562
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D206516at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.750