DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9287 and Ces2g

DIOPT Version :9

Sequence 1:	NP_609244.1	Gene:	CG9287 / 34194	FlyBaseID:	FBgn0032057	Length:	625	Species:	Drosophila melanogaster
Sequence 2:	NP_001099645.1	Gene:	Ces2g / 291952	RGDID:	1308358	Length:	560	Species:	Rattus norvegicus

Alignment Length:	567	Identity:	160/567 - (28%)
Similarity:	233/567 - (41%)	Gaps:	103/567 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 WWQIV--SLLLVLQSVVESRVRGRQYDEEKDTIVELPTLGSIQGKILETAWTKREVLQFVDVRYA 67
            |...|  .|||:|     ..|:| |:..|...|....| |.:|||:..:...|..|..|:.:.:|
  Rat     9 WLNAVLFGLLLLL-----IHVQG-QHSPESSPIRNTHT-GQVQGKLTHSKDFKSGVHTFLGIPFA 66

  Fly    68 EPPTGLHRFKAPRPIEPWEDVMDATAEKIGCPSVV--SMDSLRR----LDDVLDVEDCLTMTITT 126
            :.|.|..||..|...|||..|.|.|::...||..|  :|:.|:.    |..|...||||.:.|..
  Rat    67 KAPVGPLRFAPPEAPEPWSGVRDGTSQSNICPQNVRMNMEGLKEMKLTLPPVSMSEDCLYLNIYA 131

  Fly   127 P---NVTSRLPVLVYIHGEYL-------YEGSNSEAPPDYLLEKDVVLVTPQYRLGPFGFLSTKT 181
            |   :..|.|||:|:|||..|       |:||...|      .:|||:||.|||||..||.||..
  Rat   132 PAHAHEGSHLPVMVWIHGGALTVGMASMYDGSMLAA------TEDVVVVTIQYRLGVLGFFSTGD 190

  Fly   182 DEIPGNAGFLDIFLALQFVKHFIKYFGGDPSRVTVAGQVGGAAIAHLLTLSPVVQRGLFHQVIYH 246
            ....||.|:||...||::|:..|.:|||:|..||:.|:..|........:|| :.:||||:.|..
  Rat   191 HHARGNWGYLDQVAALRWVQQNIAHFGGNPDCVTIFGESAGGLSVSSHVVSP-MSKGLFHRAIME 254

  Fly   247 SGSAIMPIFLEEDPRKHAQEIAKKADCKMVTVRDLNTCLMELTALELLTAFMEHALEKSDLGIGH 311
            ||.|:||..:........|.:.|.:.|:.:....|..||...:..::.....|..:
  Rat   255 SGVALMPGTIFNFSEMVYQMVVKLSGCEAMDPESLVHCLRGKSEEQITVISKEFQM--------- 310

  Fly   312 TGGIQFTIGGPSGVLPKHPYDLMLETNFSYPAMGGCPKNAGSRVLNEIVDNDFEGKIPDDEYNTY 376
               |...:.|.  .||.||.:|:...:| :|.    |...|       .:||..|.|......:.
  Rat   311 ---IPAVVDGE--FLPNHPQELLASADF-HPV----PSIIG-------FNNDEYGWIVPKVIGSA 358

  Fly   377 NYIDHVIRQTV-----GTDKTMLLTSFVTHDFFNRNLMENGTFD-----TLIPRLIDVAGTLNHK 431
            ..|..:.|:.:     .|...|:|....: |.    |||....|     ||..:..::.......
  Rat   359 QTIKGITRENLQAFLKDTAPQMMLPPECS-DL----LMEEYMGDIEDPQTLQAQFTEMMEDFMFV 418

  Fly   432 LPVLLALNMNNKHNPDNTFLYSFDYAGEFNRYKEM----------DEETNLQSPFKAGVSLTDEA 486
            :|.|........|.|  .:.|.|.:...|  .|::          ||...:...|..|:.|
  Rat   419 IPSLQVARFQRSHAP--VYFYEFQHQSSF--LKDIRPPHVKADHGDEVPFVFGSFFWGMKL---- 475

  Fly   487 LYLFPYPEHVTRLSRPDQSMAHRMVELWTNFVISGNPLGSARVGYWP 533
                       .|:..::.:..||::.|.||...||| .|..:.|||
  Rat   476 -----------NLTEGEKLLNRRMMKYWANFARYGNP-NSNSLPYWP 510

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9287	NP_609244.1	COesterase	31..558	CDD:278561	151/539 (28%)
Ces2g	NP_001099645.1	COesterase	31..539	CDD:278561	151/539 (28%)
Ces2g	NP_001099645.1	Aes	<129..>232	CDD:223730	45/108 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166336290
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.740