Protein Alignment CG9287 and NLGN1

DIOPT Version :10

• Sequence 1: NP_609244.1
• Gene: CG9287 / 34194
• FlyBaseID: FBgn0032057
• Length: 625
• Species: Drosophila melanogaster
• Sequence 2: NP_001352852.1
• Gene: NLGN1 / 22871
• HGNCID: 14291
• Length: 843
• Species: Homo sapiens
• Alignment Length: 574
• Identity: 159/574 - (27%)
• Similarity: 239/574 - (41%)
• Gaps: 130/574 - (22%)

  Fly    30 EEKDTIVELPTLGSIQGKILETAWTKRE--------VLQFVDVRYAEPPTGLHRFKAPRPIEPWE 86
            ::.|.:| ....|.|:|       .|:|        |:||:.|.||.||||..||:.|.|..||.
Human    49 DDVDPLV-ATNFGKIRG-------IKKELNNEILGPVIQFLGVPYAAPPTGERRFQPPEPPSPWS 105

  Fly    87 DVMDATAEKIGCPSVVSMDSLRRLDDV---------LDV---------EDCLTMTITTPNVTSRL 133
            |:.:||.....||..: :|.  ||.:|         |||         ||||.:.|..|.....|
Human   106 DIRNATQFAPVCPQNI-IDG--RLPEVMLPVWFTNNLDVVSSYVQDQSEDCLYLNIYVPTEDGPL 167

  Fly   134 --------------------------PVLVYIHGEYLYEGSNSEAPPDYLLE-KDVVLVTPQYRL 171
                                      ||:|||||....||:.:......|.. .:|:::|..|||
Human   168 TKKQTDDLGDNDGAEDEDIRDSGGPKPVMVYIHGGSYMEGTGNLYDGSVLASYGNVIVITVNYRL 232

  Fly   172 GPFGFLSTKTDEIPGNAGFLDIFLALQFVKHFIKYFGGDPSRVTVAGQVGGAAIAHLLTLSPVVQ 236
            |..|||||......||.|.||:..||::....|.:|||||.|:||.|...|.:..:|||||...:
Human   233 GVLGFLSTGDQAAKGNYGLLDLIQALRWTSENIGFFGGDPLRITVFGSGAGGSCVNLLTLSHYSE 297

  Fly   237 --------RGLFHQVIYHSGSAIMPIFLEEDPRKHAQEIAKKADCKMVTVRDLNTCLMELTALEL 293
                    :|||.:.|..||:|:....:...|.|:|:.:|.|..|.:....:|..||.:....||
Human   298 GNRWSNSTKGLFQRAIAQSGTALSSWAVSFQPAKYARMLATKVGCNVSDTVELVECLQKKPYKEL 362

  Fly   294 LTAFMEHALEKSDLGIGHTGGIQFTIG-GP---SGVLPKHPYDLMLETNF-SYPAMGGCPKNAGS 353
            :...::.|              ::.|. ||   ..|:|..|..||.:..| :|..|.|..:..|.
Human   363 VDQDIQPA--------------RYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGL 413

  Fly   354 RVLNEIVDNDFEGKIPDDEYNTYNYIDHVIRQTVGTDKTMLLTSFVTHDFFNRNLMENGTFDTLI 418
            :.:..|||:|......|.::...|::|::.....|.|.......|:..|:.:|:..|... .||:
Human   414 KFVENIVDSDDGISASDFDFAVSNFVDNLYGYPEGKDVLRETIKFMYTDWADRHNPETRR-KTLL 477

  Fly   419 PRLIDVAGTLNHK--LPVLLALNM-NNKHNPDNTFLYSFDYAGEFNRYKEMDEETNLQSPFKAGV 480
            ....|      |:  .|.:...:: :|..:|  |:.|:|        |.....:   |.|..|..
Human   478 ALFTD------HQWVAPAVATADLHSNFGSP--TYFYAF--------YHHCQTD---QVPAWADA 523

  Fly   481 SLTDEALY-----------LFPYPEHVTRLSRPDQSMAHRMVELWTNFVISGNP 523
            :..||..|           |||     ...|:.|..::..::..||||..:|:|
Human   524 AHGDEVPYVLGIPMIGPTELFP-----CNFSKNDVMLSAVVMTYWTNFAKTGDP 572

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9287	NP_609244.1	COesterase	33..558	CDD:395084	159/571 (28%)
NLGN1	NP_001352852.1	COesterase	52..626	CDD:395084	159/571 (28%)