Protein Alignment CG9287 and NLGN4Y

DIOPT Version :9

• Sequence 1: NP_609244.1
• Gene: CG9287 / 34194
• FlyBaseID: FBgn0032057
• Length: 625
• Species: Drosophila melanogaster
• Sequence 2: NP_001352513.1
• Gene: NLGN4Y / 22829
• HGNCID: 15529
• Length: 836
• Species: Homo sapiens
• Alignment Length: 584
• Identity: 160/584 - (27%)
• Similarity: 247/584 - (42%)
• Gaps: 116/584 - (19%)

  Fly     3 LLWWQIVSLLLVLQSVVESRVRGRQYDEEKDTIVELPTLGSIQGKI--LETAWTKREVL----QF 61
            |||   ::.|.:..::::|:.   ||          |.:.:..|||  |.|. ...|:|    |:
Human    26 LLW---ITALAIKFTLIDSQA---QY----------PVVNTNYGKIQGLRTP-LPSEILGPVEQY 73

  Fly    62 VDVRYAEPPTGLHRFKAPRPIEPWEDVMDATAEKIGCPSVVSMDSLRRLDDVLDV---------- 116
            :.|.||.||||..||:.|.....|..:.:||.....||.  .:|....|.|:|.:
Human    74 LGVPYASPPTGERRFQPPESPSSWTGIRNATQFSAVCPQ--HLDERFLLHDMLPIWFTTSLDTLM 136

  Fly   117 -------EDCLTMTITTP-----NV---------------------TSRLPVLVYIHGEYLYEGS 148
                   ||||.:.|..|     |:                     .|:.||:|||||....||:
Human   137 TYVQDQNEDCLYLNIYVPMEDGTNIKRNADDITSNDHGEDKDIHEQNSKKPVMVYIHGGSYMEGT 201

  Fly   149 NSEAPPDYLLE-KDVVLVTPQYRLGPFGFLSTKTDEIPGNAGFLDIFLALQFVKHFIKYFGGDPS 212
            .:......|.. .:|:::|..||||..|||||......||.|.||...||::::..:..|||||.
Human   202 GNMIDGSILASYGNVIVITINYRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPK 266

  Fly   213 RVTVAGQVGGAAIAHLLTLSPVVQRGLFHQVIYHSGSAIMPIFLEEDPRKHAQEIAKKADCKMVT 277
            |||:.|...||:...|||||. ...|||.:.|..||:|:....:...|.|:.:.:|.|..|.|:.
Human   267 RVTIFGSGAGASCVSLLTLSH-YSEGLFQKAIIQSGTALSSWAVNYQPAKYTRILADKVGCNMLD 330

  Fly   278 VRDLNTCLMELTALELLTAFMEHALEKSDLGIGHTGGIQFTIGGP---SGVLPKHPYDLMLETNF 339
            ..|:..||......||:...:..|          |..|.|   ||   ..|:|..|..||.:..|
Human   331 TTDMVECLKNKNYKELIQQTITPA----------TYHIAF---GPVIDGDVIPDDPQILMEQGEF 382

  Fly   340 -SYPAMGGCPKNAGSRVLNEIVDNDFEGKIPDD-EYNTYNYIDHVIRQTVGTDKTMLLTSFVTHD 402
             :|..|.|..:..|.:.::.||||: :|..|:| :::..|::|::.....|.|.......|:..|
Human   383 LNYDIMLGVNQGEGLKFVDGIVDNE-DGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETIKFMYTD 446

  Fly   403 FFNRNLMENGTFDTLIPRLIDVAGTLNHK--LPVLLALNMNNKHNPDNTFLYSFDYAGEFNRYKE 465
            :.::...|... .||:....|      |:  .|.:...:::.::. ..|:.|:|        |..
Human   447 WADKENPETRR-KTLVALFTD------HQWVAPAVATADLHAQYG-SPTYFYAF--------YHH 495

  Fly   466 MDEETNLQSPFKAGVSLTDEALYLFPYPE------HVTRLSRPDQSMAHRMVELWTNFVISGNP 523
            ...|   ..|..|..:..||..|:|..|.      .....|:.|..::..::..||||..:|:|
Human   496 CQSE---MKPSWADSAHGDEVPYVFGIPMIGPTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDP 556

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9287	NP_609244.1	COesterase	31..558	CDD:278561	153/556 (28%)
NLGN4Y	NP_001352513.1	COesterase	46..610	CDD:306613	153/548 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165142832
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840