Protein Alignment CG9287 and cest-16

DIOPT Version :10

• Sequence 1: NP_609244.1
• Gene: CG9287 / 34194
• FlyBaseID: FBgn0032057
• Length: 625
• Species: Drosophila melanogaster
• Sequence 2: NP_741812.2
• Gene: cest-16 / 180905
• WormBaseID: WBGene00020330
• Length: 697
• Species: Caenorhabditis elegans
• Alignment Length: 635
• Identity: 151/635 - (23%)
• Similarity: 255/635 - (40%)
• Gaps: 142/635 - (22%)

  Fly    12 LLVLQSVVESRVRGRQYDEEKDTIVELPTLGSIQGKILETAWTKREVLQFVDVRYAEPPTGLHRF 76
            ||:|.:.:.|...|:..::.:...||   .|.::|.|...  ..:.:..|..|.|||||.|..||
 Worm     4 LLLLLTFIFSWANGQLLEKSRSVWVE---QGLVRGNIYNI--DGKHIQIFRGVPYAEPPIGELRF 63

  Fly    77 KAPRPIEPWEDVMDATAEKIGCPSVVSM-----DSLRRLDDVLDVEDCLTMTITTP----NVTSR 132
            |.|.....|...:.|.  :.|.|.:..|     |...:.:.....||||.:.:.:|    :.:..
 Worm    64 KPPVKKTRWHQELPAV--EYGPPCLQFMDFHKNDKFAKTNMDRQSEDCLYLNVFSPYDTDDESKT 126

  Fly   133 LPVLVYIHGEYLYEGS-----NSEAPPDYLLEKDVVLVTPQYRLGPFGFLSTKT-DEIPGNAGFL 191
            .|:||:|||.....||     :.|.....::.|.:..|:..|||||.||::.:. |::.||.|..
 Worm   127 YPILVWIHGGSFLAGSADTGIDMEVIAANIVSKGIAFVSINYRLGPLGFMNYQNGDKLEGNFGIW 191

  Fly   192 DIFLALQFVKHFIKYFGGDPSRVTVAGQVGGAAIAHLLTLSPVVQRGLFHQVIYHSGSAI----- 251
            |:.:|||:::..||.|.|||::|||.|:..|.|.:.||.|||... ||.||.|..|||::
 Worm   192 DMVMALQWIQSNIKQFNGDPTKVTVMGESAGGAASSLLALSPKTS-GLLHQAIIMSGSSMAGWAI 255

  Fly   252 ----MPIF--------------LEEDPRKH---------AQEIAKKADCKMVTVRDLNTCLMELT 289
                .|.:              :.||..|.         ...:.:.|.|....|: :|....::|
 Worm   256 HRHSQPAYSVDNLVAYFRCEKWINEDDTKEVVGDEYQHLTHSVIRSALCNYQNVK-INCLTDDMT 319

  Fly   290 ALELLTA------FMEHALEK---SDLGIGHTGGIQFTIGG----PSGVLPKHPYDLMLETNFSY 341
            .::.:..      |......|   ::||:.     :..:.|    .|||       .::..|...
 Worm   320 QMDKMNCLRKELNFSSPLFRKALAAELGVS-----KMVVDGDLVPSSGV-------SLVRNNARI 372

  Fly   342 PAMGG-CPKNAGSRVLNEIVDNDFEG-KIPDDEYNTYNYIDHVIRQTVG---TDKTMLLTSFVT- 400
            |.|.| ..|..|.:.......:..:| |..|.|...|..||:...:|..   .:.|:.|.:..|
 Worm   373 PIMTGVARKEWGHKKAMFYNMHQRDGLKRSDVEEQVYRIIDNSFHETASEKLANSTVQLIANATI 437

  Fly   401 --------HDFFNRNLME-----NGTFDTLIPRLIDVAGTLNHKLPVLLALNMNNKHNPDNTFLY 452
                    ::|....::.     ....:.:.|...:||..::..:||               :||
 Worm   438 VRYLETPNNEFIADQVVGALQKLESDIEFVAPCEREVAAYVDKGVPV---------------YLY 487

  Fly   453 SFDYAGEFNRYKEMDEETNLQSPF-----------------KAGVSLTDEALYLFP--YPEH--V 496
            ||||.   .:...::.|..:.|.|                 ||.....|.| ::|.  |..:  :
 Worm   488 SFDYV---PKSPILESERKIYSLFGTKPVEMKRTEKSEILEKAAFHGLDHA-FIFSKGYSSNFEI 548

  Fly   497 TRLSRPDQSMAHRMVELWTNFVISGNPLGSARVGYWPPMTTLYGPYMRID 546
            :..::.:::|:..:..:.||||.:|:| .:.|.. ||..:.....|:.:|
 Worm   549 SPYTKREETMSKILCTMLTNFVKNGDP-STTRFS-WPIFSGNSSQYVSLD 596

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9287	NP_609244.1	COesterase	33..558	CDD:395084	146/614 (24%)
cest-16	NP_741812.2	alpha/beta hydrolases	23..608	CDD:473884	146/616 (24%)