Protein Alignment CG9287 and cest-2.2

DIOPT Version :10

• Sequence 1: NP_609244.1
• Gene: CG9287 / 34194
• FlyBaseID: FBgn0032057
• Length: 625
• Species: Drosophila melanogaster
• Sequence 2: NP_001256567.1
• Gene: cest-2.2 / 179917
• WormBaseID: WBGene00013874
• Length: 672
• Species: Caenorhabditis elegans
• Alignment Length: 701
• Identity: 162/701 - (23%)
• Similarity: 261/701 - (37%)
• Gaps: 179/701 - (25%)

  Fly     4 LWWQIVSLLLVLQSVVESRVRGRQYDEEKDTIVELPT-LGSIQGKILETAWT---KREVLQFVDV 64
            ::::...|..:||:|             :.|.|:|.: .|:|:|:.|..:::   .:..:.|..|
 Worm     1 MFFRFFILWAILQNV-------------RSTKVKLSSRTGTIEGRTLTASYSPLGNQTGIVFFGV 52

  Fly    65 RYAEPPTGLHRFKAPRPIEPWEDVMDATAEKIGCPSVVSMDSLRRLDDVLD---VEDCLTMTITT 126
            .|.|||.|..||:.|||.:||:.|::|...|..|.|    |..:...:.:.   .||||...:.|
 Worm    53 PYVEPPVGNLRFRKPRPPKPWDGVLEAKEYKAACMS----DQKKTYKNGVGGPVSEDCLYANVFT 113

  Fly   127 PNVT---SRLPVLVYIHGEYLYEGSNSEAPPDYLLE------KDVVLVTPQYRLGPFGFLSTKTD 182
            ....   ....|::.|||......|.|...|:.::.      :::|:||..||||.||......|
 Worm   114 NQYCLEHKNCSVMLTIHGGRFVIESASAYDPEIIINNFVGQGRNIVVVTFNYRLGLFGLGMLNGD 178

  Fly   183 EIPGNAGFLDIFLALQFVKHFIKYFGGDPSRVTVAGQVGGAAIAHLLTLSPVVQRGLFHQVIYHS 247
            ....|.|..||...:::.:..||.||||..|:|:.|...||......:.|| :.:||.||.|..|
 Worm   179 NQDTNFGLYDILEVVRWTRKEIKNFGGDKDRITMQGHSAGAVFTAAFSTSP-LSKGLIHQQIIMS 242

  Fly   248 GSAIMPIFLEEDPRKHAQEIAKKADC----------KMVTVRDLNTCLMELTALELLTAFMEHAL 302
            .|  |....::...|....:|:...|          ..|.|....|||...:|.::|.|.: :.|
 Worm   243 AS--MSNLSKKSNVKELTVVARIVGCLPDEHGFPKLSNVEVEKAYTCLRSKSAQQILDAQL-YML 304

  Fly   303 EKSD--LGIGHTGGIQFTIGGPSGVLPKHPYDLMLETNFSYPAMGGCPKNAGSRVLNEIVDNDFE 365
            ..:.  :|.||..|| :.:..|         |.:..||..||             :|.::... .
 Worm   305 RNTTYYIGQGHIDGI-YQVDYP---------DNLYATNSIYP-------------INTMIGTT-T 345

  Fly   366 GKIPDDEYNTYNYIDHVIRQTVGTDKTMLLTSFVTHDFFN------------RNLMENGTFDTLI 418
            .::.|..|        ::.......|.:||.:...|..:.            ||..:||
 Worm   346 AELMDSRY--------IVDPKNTGKKEILLQNLCEHIGYELYKEPEEFSQKCRNFYKNG------ 396

  Fly   419 PRLIDVAGTLNHKLPVLL-ALNMNNKHN--PDNTFLYSFDYAGEFNRYKEMDEE----------- 469
                :.|.:|...:.... |:.:.|.|:  ..|.|:|||||....|.||:.|:.
 Worm   397 ----EDAKSLGDDMEFYYGAIQLANVHSSKDTNVFVYSFDYKEAGNAYKKYDKSLSPKHGEDFAY 457

  Fly   470 ---TNLQSPFKAGVSLTD---EALYLFPYPEHVTRLSRP----DQSMA--------HRMVELWTN 516
               ||     :...|..|   |.:|...:.:.| ....|    ||..|        :.:::...|
 Worm   458 AFGTN-----RGNFSTKDYVIEYIYSGMFADFV-NFGDPSPLEDQEWAQYTPEKREYFLIDFDKN 516

  Fly   517 FVISGNPLGSARVGYWPP-------------------------MTTLYGPYM-RIDDTMTIGGNY 555
            |.:.|     .:..|:|.                         :..|..|.| .::...|.....
 Worm   517 FTMPG-----MKDHYYPKALEFWSTCGSKSFKEHFSPSVDIFIIGNLLNPIMSHLNHNETGPDKT 576

  Fly   556 FTEFSATLSDEEQGHSLIREVYYL-------RSRSRKRALNKRRKQLAKSN 599
            |.:|....::.|:...|::.|..|       |.||.|..:.|....|.|.|
 Worm   577 FEQFDKLYNEREEFLKLLKAVRKLEIQKKMWRGRSSKDLMLKELVDLEKIN 627

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9287	NP_609244.1	COesterase	33..558	CDD:395084	145/622 (23%)
cest-2.2	NP_001256567.1	alpha/beta hydrolases	25..534	CDD:473884	137/569 (24%)