Protein Alignment CG9287 and cest-2.1

DIOPT Version :9

• Sequence 1: NP_609244.1
• Gene: CG9287 / 34194
• FlyBaseID: FBgn0032057
• Length: 625
• Species: Drosophila melanogaster
• Sequence 2: NP_506508.2
• Gene: cest-2.1 / 179916
• WormBaseID: WBGene00013875
• Length: 675
• Species: Caenorhabditis elegans
• Alignment Length: 713
• Identity: 160/713 - (22%)
• Similarity: 273/713 - (38%)
• Gaps: 190/713 - (26%)

  Fly     1 MQLLWWQIVSLLLVLQSVVESRVRGRQYDEEKDTIVELPTLGSIQGKILETAWT---KREVLQFV 62
            |.||:..::|.||.:..               .|.|:|.| |:|:||||.:.::   ....:.|:
 Worm     1 MVLLFLFLLSTLLHISI---------------STRVQLST-GTIEGKILTSTYSPLGNHTGIGFL 49

  Fly    63 DVRYAEPPTGLHRFKAPRPIEPWEDVMDATAEKIGCPSVVSMDSLRRLDDVLDVEDCLTMTITTP 127
            .:.:.|||.|..||:.|||..||:.:::....|..|.|.........:...:. ||||...:.|.
 Worm    50 GIPFVEPPAGNLRFRKPRPPIPWDGILETKEYKPACMSDAKKTYKNGVGGPIS-EDCLYANVFTN 113

  Fly   128 NVTSR---LPVLVYIHGEYLYEGSNSEAPPDYLLE------KDVVLVTPQYRLGPFGFLSTKTDE 183
            ....:   ..|::.:||..:...|.|...|:.|:.      :::|:||..||||.|||.....::
 Worm   114 QYCMKRKNCSVMIVVHGGRILTESASAFNPEILVNNFVGQGRNIVVVTFNYRLGTFGFGVLNGEK 178

  Fly   184 IPGNAGFLDIFLALQFVKHFIKYFGGDPSRVTVAGQVGGAAIAHLLTLSPVVQRGLFHQVIYHSG 248
            ...|.|..|:..|:::.:..:..|||:..::|:.|...|.::....|.|| :.:|:.:|.|..||
 Worm   179 GDSNVGMFDMLEAVKWTRKEVHNFGGNKDKLTMVGHSAGGSLVGAFTSSP-LSKGMLNQQIIMSG 242

  Fly   249 SAIMPIFLEEDPRKHAQEIAKKADC--------KMVTVRDLNT--CLMELTALELLTAFMEHALE 303
            :......|..  .|....:|:||.|        |:..||...|  ||..::|.|:|.|.: ..|:
 Worm   243 ALYQMGKLAN--FKGMTAMAQKAGCLPEVFGFRKLSQVRIDKTYSCLRNISAQEVLDAQL-WVLQ 304

  Fly   304 KSD--LGIGHTGGIQFTIGGPSGVLPK---HPYDLMLETNFSY---PAMGGCPKNAGSRVLNEIV 360
            .:.  :.:.|..| :|.:.....:|..   ||.:.|:.|..:.   |......|||..:  .|::
 Worm   305 NTTYYISVPHIDG-EFLLNYSDEILASGTIHPINSMIGTTTAELRDPIYINDLKNADKK--EELL 366

  Fly   361 DNDFE--GKIPDDEYNTYNYIDHVIRQTV-----GTDKTMLLTSFVTHDFFNRNLMENGTFDTLI 418
            .|..|  |      |..|...:...|:..     |.|...|......:|.
 Worm   367 KNLCEHIG------YELYTEPEEFSRKCQKFYGNGDDAQFLADDMEFYDG--------------- 410

  Fly   419 PRLIDVAGTLNHKLPVLLALNMNNKHNPDNT--FLYSFDY--AG-EFNRYKEMDEETNLQSPFKA 478
                              ::.:.|.|...||  |:||:||  || .|.:|.:.....:
 Worm   411 ------------------SIKVANAHASKNTKVFMYSYDYKDAGPAFKKYAQAPPPHH------- 450

  Fly   479 GVSLTDEALYLFPYPEHVTRLSRPDQSMAHRMVE-----LWTNFVISGNPLGSARVGYWPPMTTL 538
                :::.:|:|       ..||.:.:....::|     ::.:||..||| ..::...|..
 Worm   451 ----SEDLIYVF-------GTSRGNFTEKDYVIEQIYSGMFADFVNFGNP-SPSKEQKWKE---- 499

  Fly   539 YGPYMR------IDDTMTIGG---NYFT---EFSATLSDE------------------------- 566
            |.|..|      .|...|:.|   .|::   ||.:|...:
 Worm   500 YSPEKREYFLIDFDKNFTMPGTRDGYYSRALEFWSTAGTKSFSEHYSPSLDSFTTGILIDPIVSH 564

  Fly   567 ------------EQGHSLIREVYYLRSRSRKRALNKRRKQLAKSNARRLQNPKLGGRKSLVKR 617
                        ||...::.|    |....|...::|:.:|.|...|:::|.  |||  :|:|
 Worm   565 MKGVATGPDKTFEQFEKMLLE----REMFLKTLKSERKLELLKEKWRKIRNG--GGR--IVER 619

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9287	NP_609244.1	COesterase	31..558	CDD:278561	136/585 (23%)
cest-2.1	NP_506508.2	COesterase	21..533	CDD:365897	136/582 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157075
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.740