Protein Alignment CG9287 and cest-5.2

DIOPT Version :10

• Sequence 1: NP_609244.1
• Gene: CG9287 / 34194
• FlyBaseID: FBgn0032057
• Length: 625
• Species: Drosophila melanogaster
• Sequence 2: NP_501021.3
• Gene: cest-5.2 / 177428
• WormBaseID: WBGene00015284
• Length: 583
• Species: Caenorhabditis elegans
• Alignment Length: 601
• Identity: 151/601 - (25%)
• Similarity: 240/601 - (39%)
• Gaps: 154/601 - (25%)

  Fly    40 TLGSIQGKILETAWTKREVLQFVDVRYAEPPTGLHRFKAPRPIEPWEDVMDATAEKIGCPSVVSM 104
            :||.::||      ...:...|..:.:|:||.|..||:.|...|.|..|.:||  :.| |:.:|.
 Worm    27 SLGRLEGK------QSGKYQLFRRIPFAKPPIGTLRFQKPESAEKWNGVWNAT--EYG-PACMSN 82

  Fly   105 DSLRRLDDVLDVEDCLTMTITTPN---VTSRLPVLVYIHGEYLYEGSNSEAPPDYLLE----KDV 162
            .:..:.......||||.:.|.|.:   .:....|:|||||..:...|.......:|||    :||
 Worm    83 STWTQSPQKWVDEDCLHVNIFTSDKCLKSKDCAVVVYIHGGEIVFDSAVMFNDTFLLESFVKQDV 147

  Fly   163 VLVTPQYRLGPFGFLSTKTDEI-PGNAGFLDIFLALQFVKHFIKYFGGDPSRVTVAGQVGGAAIA 226
            :||.|.:|||.|...:.....| |.|....||.||.:|||..|..||||..::|:.|...|..||
 Worm   148 ILVIPAFRLGIFSHFTVHDQNIAPNNLALYDIILAQEFVKSEIHNFGGDIQKITLFGHSYGGTIA 212

  Fly   227 HLLTLSPVVQR--GLFHQVIYHSGSAIMPIFLEEDPRKHAQEIAKKADCKMVT--VRDLN----- 282
            .::..|..:.:  .||.::|..|.:.......|:..|  :..:.|.|.|.:.|  .|.:|
 Worm   213 SMMAFSSEINQDLSLFQRIIVMSANQYFDTLEEQIER--SDRVVKHAGCSVPTNLARKMNRSQKE 275

  Fly   283 ----TCLMELTALELLTAFMEHALEKS---DLGIGHTGGIQFTIGGPSGVLPKHPYDLMLETNFS 340
                .||.:|:.:|||:  ::.:||::   |:|       ...:.||  :.|......|||:...
 Worm   276 KYMMKCLQKLSGMELLS--VQRSLEEAGYPDIG-------NLVLRGP--LFPDVTSLEMLESPKM 329

  Fly   341 YPAMGGCPKNAGSRVLNEIVDNDFEGKIPDDEYNTYNYIDHVIRQTVGTDKTMLLTSFVTHDFFN 405
            .|.:.||.|              ||.   |||..|     |.|.:..|      |.:.:..|...
 Worm   330 IPMLAGCTK--------------FES---DDEDET-----HFIGKHFG------LENPIECDEKY 366

  Fly   406 RNLMENGTFDTLIPRLIDVAGTLNHK-------LPVLLALNMNNKHNPDNTFLYSFDYAGEFNRY 463
            |..:|||.||           ..||.       :|..|.::...||... .:||.|.|.
 Worm   367 RKDLENGIFD-----------RQNHSDKTQAIMVPTKLRVDQLRKHGVP-AYLYEFTYP------ 413

  Fly   464 KEMDEETNLQSPFKAGVSLTDEALYLF---PYPEHVTRLSRPDQSMAHRMVELWTNFVISGNPLG 525
                     :..|.     ||:..|:.   |:.:        |::..| :.:::.|.:|:....|
 Worm   414 ---------KHAFH-----TDDLYYIMGIHPFEK--------DENEEH-LEKVYRNMLINFIKFG 455

  Fly   526 SARVG--------------YWPPMTTLYGPYM--RIDDTMTIGGNYF----TEFSATLSDEEQGH 570
            ...:|              ||.. ||...|.|  |.::.:|   ||:    .|:...::..::..
 Worm   456 EPGMGFEMSDLNESTYFEIYWNE-TTGQKPRMRKRFEENIT---NYWLKEMMEYDRNITKAKKNQ 516

  Fly   571 SLIR-----EVYYLRS 581
            ..|:     |.:|::|
 Worm   517 RSIKPVFKTEQFYVKS 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9287	NP_609244.1	COesterase	33..558	CDD:395084	146/571 (26%)
cest-5.2	NP_501021.3	alpha/beta hydrolases	21..498	CDD:473884	145/565 (26%)