DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9287 and Ces1g

DIOPT Version :9

Sequence 1:	NP_609244.1	Gene:	CG9287 / 34194	FlyBaseID:	FBgn0032057	Length:	625	Species:	Drosophila melanogaster
Sequence 2:	NP_067431.2	Gene:	Ces1g / 12623	MGIID:	88378	Length:	565	Species:	Mus musculus

Alignment Length:	598	Identity:	161/598 - (26%)
Similarity:	250/598 - (41%)	Gaps:	128/598 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 PTLGSIQGKILETAWT----KREVLQFVDVRYAEPPTGLHRFKAPRPIEPWEDVMDATAEKIGCP 99
            |.:.::.||:|....|    .:.|..|:.|.:|:||.|..||..|.|.|||..|...|:....|
Mouse    24 PVVHTVHGKVLGKYVTLEGFSQPVAVFLGVPFAKPPLGSLRFAPPEPAEPWSFVKHTTSYPPLC- 87

  Fly   100 SVVSMDSLRRLDDVLD----------VEDCLTMTITTP---NVTSRLPVLVYIHGEYL-YEGSNS 150
             ..:.::..||.::..          .||||.:.|.||   ...|||||:|:|||..| .:|:::
Mouse    88 -YQNPEAALRLAELFTNQRKIIPHKFSEDCLYLNIYTPADLTQNSRLPVMVWIHGGGLVIDGAST 151

  Fly   151 EAPPDYLLEKDVVLVTPQYRLGPFGFLSTKTDEIPGNAGFLDIFLALQFVKHFIKYFGGDPSRVT 215
            .......:.::||:|..|||||.:||.||:.:...||.|.||...||.:|:..|..|||:|..||
Mouse   152 YDGVPLAVHENVVVVVIQYRLGIWGFFSTEDEHSRGNWGHLDQVAALHWVQDNIANFGGNPGSVT 216

  Fly   216 VAGQVGGAAIAHLLTLSPVVQRGLFHQVIYHSGSAIMPIFLEEDPRKHAQEIAKKADCKMVTVRD 280
            :.|:..|.....:|.|||:. :.|||:.|..|.....|.......|..|::||..|.||..|...
Mouse   217 IFGESAGGESVSVLVLSPLA-KNLFHRAIAQSSVIFNPCLFGRAARPLAKKIAALAGCKTTTSAA 280

  Fly   281 LNTCLMELTALELLTAFMEHALEKSDLGIGHTGGIQFTIGGP-----------SGV-LPKHPYDL 333
            :..||.:.|..|||...::...          |.:.| :|.|           .|| |||.|.::
Mouse   281 MVHCLRQKTEDELLEVSLKMKF----------GTVDF-LGDPRESYPFLPTVIDGVLLPKAPEEI 334

  Fly   334 MLETNF-SYPAMGGCPKNAGSRVLNEIVDNDFEGKIPDDE---------YNTYNYIDHVIRQTV- 387
            :.|.:| :.|.|.|..|:....::...:|.....:..|.:         |...|..:.:|...:
Mouse   335 LAEKSFNTVPYMVGINKHEFGWIIPMFLDFPLSERKLDQKTAASILWQAYPILNISEKLIPAAIE 399

  Fly   388 ----GTDKTMLLTSFVTHDFFNRNLMENGTFDTLIPRLIDVAGTLNHKLP-VLLALNMNNKHNPD 447
                ||:....:|     |.|                 :|:.|.:...:| |:::.:..:...|
Mouse   400 KYLGGTEDPATMT-----DLF-----------------LDLIGDIMFGVPSVIVSRSHRDAGAP- 441

  Fly   448 NTFLYSFDYAGEF---NRYKEM--DEETNLQS----PF-KAGVSLTDEALYLFPYPEHVTRLSRP 502
             |::|.:.|...|   :|.:|:  |....|.|    || |.|.|            |....||:
Mouse   442 -TYMYEYQYRPSFVSDDRPQELLGDHADELFSVWGAPFLKEGAS------------EEEINLSK- 492

  Fly   503 DQSMAHRMVELWTNFVISGNPLGSARVGYWPPMTTLYGPYM----------RIDDTMTIGGNYFT 557
                  .:::.|.||..:|||.|.. :.:||......| |:          |:.|...   :::|
Mouse   493 ------MVMKFWANFARNGNPNGEG-LPHWPEYDQKEG-YLQIGVPAQAAHRLKDKEV---DFWT 546

  Fly   558 EFSATLSDEEQGH 570
            |..|..:.|...|
Mouse   547 ELRAKETAERSSH 559

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9287	NP_609244.1	COesterase	31..558	CDD:278561	156/584 (27%)
Ces1g	NP_067431.2	COesterase	24..545	CDD:278561	156/582 (27%)
Ces1g	NP_067431.2	Aes	<121..>239	CDD:223730	47/118 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832622
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D206516at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.750