Protein Alignment CG9287 and Ache

DIOPT Version :10

• Sequence 1: NP_609244.1
• Gene: CG9287 / 34194
• FlyBaseID: FBgn0032057
• Length: 625
• Species: Drosophila melanogaster
• Sequence 2: XP_036020624.1
• Gene: Ache / 11423
• MGIID: 87876
• Length: 616
• Species: Mus musculus
• Alignment Length: 601
• Identity: 157/601 - (26%)
• Similarity: 242/601 - (40%)
• Gaps: 137/601 - (22%)

  Fly    11 LLLVLQSVV--ESRVRGRQYDEEKDTIVELPTLGSIQGKILETAWTKREVLQFVDVRYAEPPTGL 73
            ||.:|.|::  .:|..||   |:...:|.:.. |.::|..|:.  ....|..|:.:.:||||.|.
Mouse    17 LLFLLLSLLGGGARAEGR---EDPQLLVRVRG-GQLRGIRLKA--PGGPVSAFLGIPFAEPPVGS 75

  Fly    74 HRFKAPRPIEPWEDVMDATAEKIGCPSVVSMDSL-------------RRLDDVLDVEDCLTMTIT 125
            .||..|.|..||..|:|||..:..|...|  |:|             |.|.     ||||.:.:.
Mouse    76 RRFMPPEPKRPWSGVLDATTFQNVCYQYV--DTLYPGFEGTEMWNPNRELS-----EDCLYLNVW 133

  Fly   126 T--PNVTSRLPVLVYIHGEYLYEGSNSEAPPD--YLLE-KDVVLVTPQYRLGPFGFLSTK-TDEI 184
            |  |...|..|||::|:|...|.|:.|....|  :|.: :..|||:..||:|.||||:.. :.|.
Mouse   134 TPYPRPASPTPVLIWIYGGGFYSGAASLDVYDGRFLAQVEGAVLVSMNYRVGTFGFLALPGSREA 198

  Fly   185 PGNAGFLDIFLALQFVKHFIKYFGGDPSRVTVAGQVGGAAIA--HLLTLSPVVQRGLFHQVIYHS 247
            |||.|.||..||||:|:..|..|||||..||:.|:..|||..  |:|:|.   .|.|||:.:..|
Mouse   199 PGNVGLLDQRLALQWVQENIAAFGGDPMSVTLFGESAGAASVGMHILSLP---SRSLFHRAVLQS 260

  Fly   248 GSAIMP--IFLEEDPRKHAQEIAKKADCKMVTV----RDLNTCLMELTALELLTAFMEHALEKSD 306
            |:...|  .....:.|:.|..:|:...|.....    .:|..||....|.:|    ::|...
Mouse   261 GTPNGPWATVSAGEARRRATLLARLVGCPPGGAGGNDTELIACLRTRPAQDL----VDHEWH--- 318

  Fly   307 LGIGHTGGIQFTIGGPSGVLPKHPYDLMLETNFSYPAMGGCPKNAGSRVLNEIVDNDFEGKIPDD 371
                              |||:       |:.|.:..:             .:||.||....|:.
Mouse   319 ------------------VLPQ-------ESIFRFSFV-------------PVVDGDFLSDTPEA 345

  Fly   372 EYNTYNYIDHVIRQTVGTDKTMLLTSFVTHDFF--NRNLMENGTF----DTLIPRLIDVAGT--- 427
            ..||.::.|..:...|..|:......:....|.  |.:|:....|    ...:|:..|:|..
Mouse   346 LINTGDFQDLQVLVGVVKDEGSYFLVYGVPGFSKDNESLISRAQFLAGVRIGVPQASDLAAEAVV 410

  Fly   428 ------LNHKLPVLLALNMN---NKHN---------------PDNTFLYSFDYAGEFNRYKEMDE 468
                  |:.:.|..|...|:   ..||               ....:.|.|::           .
Mouse   411 LHYTDWLHPEDPTHLRDAMSAVVGDHNVVCPVAQLAGRLAAQGARVYAYIFEH-----------R 464

  Fly   469 ETNLQSPFKAGVSLTDEALYLFPYP-EHVTRLSRPDQSMAHRMVELWTNFVISGNPLG--SARVG 530
            .:.|..|...||....|..::|..| :.....:..::..|.|:::.||||..:|:|..  .::..
Mouse   465 ASTLTWPLWMGVPHGYEIEFIFGLPLDPSLNYTTEERIFAQRLMKYWTNFARTGDPNDPRDSKSP 529

  Fly   531 YWPPMTTLYGPYMRID 546
            .|||.||....|:.::
Mouse   530 QWPPYTTAAQQYVSLN 545

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9287	NP_609244.1	COesterase	33..558	CDD:395084	149/577 (26%)
Ache	XP_036020624.1	COesterase	37..563	CDD:395084	149/578 (26%)