Protein Alignment CG9287 and CEL

DIOPT Version :10

• Sequence 1: NP_609244.1
• Gene: CG9287 / 34194
• FlyBaseID: FBgn0032057
• Length: 625
• Species: Drosophila melanogaster
• Sequence 2: NP_001798.3
• Gene: CEL / 1056
• HGNCID: 1848
• Length: 753
• Species: Homo sapiens
• Alignment Length: 606
• Identity: 143/606 - (23%)
• Similarity: 241/606 - (39%)
• Gaps: 151/606 - (24%)

  Fly    41 LGSI--QGKILETAWTKREVLQ-----FVDVRYAEPPTGLHRFKAPRPIEPWEDVMDATAEKIGC 98
            ||::  :|..:|....|..:|.     |..:.:|.|...|..   |:|...|:..:.|...|..|
Human    23 LGAVYTEGGFVEGVNKKLGLLGDSVDIFKGIPFAAPTKALEN---PQPHPGWQGTLKAKNFKKRC 84

  Fly    99 -PSVVSMDSLRRLDDVLDVEDCLTMTITTP----NVTSRLPVLVYIHG---------------EY 143
             .:.::.||      ....||||.:.|..|    .|:..|||:::|:|               .|
Human    85 LQATITQDS------TYGDEDCLYLNIWVPQGRKQVSRDLPVMIWIYGGAFLMGSGHGANFLNNY 143

  Fly   144 LYEGSNSEAPPDYLLEKDVVLVTPQYRLGPFGFLSTKTDEIPGNAGFLDIFLALQFVKHFIKYFG 208
            ||:|.      :.....:|::||..||:||.|||||....:|||.|..|..:|:.:||..|..||
Human   144 LYDGE------EIATRGNVIVVTFNYRVGPLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAAFG 202

  Fly   209 GDPSRVTVAGQVGGAAIAHLLTLSPVVQRGLFHQVIYHSGSAIMPIFLEEDPRKHAQEIAKKADC 273
            |||:.:|:.|:..|.|...|.|||| ..:||..:.|..||.|:.|..::::|...|:::|:|..|
Human   203 GDPNNITLFGESAGGASVSLQTLSP-YNKGLIRRAISQSGVALSPWVIQKNPLFWAKKVAEKVGC 266

  Fly   274 KMVTVRDLNTCLMELTALELLTAFMEHALEKSDLGIGHTGGIQFTIGGPSGVLPKHPYDLMLETN 338
            .:.....:..|| ::|....||...:..|          .|:::.:....|.:|
Human   267 PVGDAARMAQCL-KVTDPRALTLAYKVPL----------AGLEYPMLHYVGFVP----------- 309

  Fly   339 FSYPAMGGCPKNAGSRVLNEIVDNDFEGKIPDDEYNTY------NYI-------DHVI------- 383
                                ::|.||   ||.|..|.|      :||       .|:.
Human   310 --------------------VIDGDF---IPADPINLYANAADIDYIAGTNNMDGHIFASIDMPA 351

  Fly   384 -----RQTVGTDKTMLLTSF----------VTHDFFNRNLMENGTFDTLIPRLIDVAGTLNHKLP 433
                 ::....|...|::.|          .|.|.:..:..::.:.:.....::|....:...:|
Human   352 INKGNKKVTEEDFYKLVSEFTITKGLRGAKTTFDVYTESWAQDPSQENKKKTVVDFETDVLFLVP 416

  Fly   434 VLLALNMNNKH-NPDNTFLYSFDYAGEFNRYKEMDEETNLQSPFKAGVSLTDEALYLFPYPEHVT 497
            ..:||..:..: ....|:.|.|.:......|           |...|....|:..|:|..|....
Human   417 TEIALAQHRANAKSAKTYAYLFSHPSRMPVY-----------PKWVGADHADDIQYVFGKPFATP 470

  Fly   498 RLSRP-DQSMAHRMVELWTNFVISGNP-LGSARV-GYWPPMTTLYGPYMRIDDTM-------TIG 552
            ...|| |::::..|:..||||..:|:| :|.:.| .:|.|.||....|:.|...|       ::.
Human   471 TGYRPQDRTVSKAMIAYWTNFAKTGDPNMGDSAVPTHWEPYTTENSGYLEITKKMGSSSMKRSLR 535

  Fly   553 GNYFTEFS------ATLSDEE 567
            .|:...::      .|::|:|
Human   536 TNFLRYWTLTYLALPTVTDQE 556

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9287	NP_609244.1	COesterase	33..558	CDD:395084	140/589 (24%)
CEL	NP_001798.3	Heparin-binding	21..121		27/106 (25%)
		COesterase	26..542	CDD:395084	138/587 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	555..753		1/2 (50%)
		17 X 11 AA tandem repeats, glycodomain, O-linked (mucin type)	559..745
		Mucin-like	584..677	CDD:464997
		Mucin-like	639..731	CDD:464997