DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Glt and LOC688542

DIOPT Version :9

Sequence 1:	NP_001245946.1	Gene:	Glt / 34193	FlyBaseID:	FBgn0001114	Length:	1026	Species:	Drosophila melanogaster
Sequence 2:	XP_038954018.1	Gene:	LOC688542 / 688542	RGDID:	1587637	Length:	559	Species:	Rattus norvegicus

Alignment Length:	579	Identity:	154/579 - (26%)
Similarity:	238/579 - (41%)	Gaps:	126/579 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 QPQEAVVQAPEVGQILGISGHKTIANRPVNAFLGIRYGTVGGGLARF---QAAQPIGYQGRVNAT 117
            |...:.::....||:.|...|....:..|:.||||.:.....|..||   :|.:|  :.|..:||
  Rat    27 QDSASPIRNTHTGQVRGSLVHVKDTDIDVHTFLGIPFAKPPVGPLRFAPPEAPEP--WSGVRDAT 89

  Fly   118 VQSPNCAQFPE-------------LDRLRLSESRGENVDDCLTLDIYAP----EGANQLPVLVFV 165
            .....|.|...             |..:.:||       |||.|:||||    ||:| |||:|::
  Rat    90 SHPAMCLQNDNMMGSEDMKIMKLILPPISMSE-------DCLYLNIYAPTHAHEGSN-LPVMVWI 146

  Fly   166 HGEML-------FDGGSEEAQPDYVLEKDVLLVSINYRLAPFGFLSALTDELPGNVALSDLQLAL 223
            ||..|       :||....|      .:||::|:|.|||...||.|...:...||....|...||
  Rat   147 HGGALTVGMASMYDGSMLAA------TEDVVVVTIQYRLGVLGFFSTGDEHARGNWGYLDQVAAL 205

  Fly   224 EWLQRNVVHFGGNAGQVTLVGQAGGATLAHALSLSGRAGNLFQQLILQSGTALNPYLIDNQPLDT 288
            .|:|:|:.|||||..:||:.|::.|.|...:..:|..:..||...|::||..:.|.||.......
  Rat   206 RWVQQNIAHFGGNPNRVTIFGESAGGTSVSSHVVSPMSQGLFHGAIMESGVVVLPDLISRSSEMV 270

  Fly   289 LSTFARLARCPPPSINPSAQGLKPLYDCLARLPTSQLVAAFEQLLLQNEHLGLTQLGGFKLVVGD 353
            ....|.|:.|       :|...:.|..||.....:::             |.:.::  ||::...
  Rat   271 YRIVANLSGC-------AAVDSETLMQCLRGKSEAEI-------------LDINKV--FKIIPAV 313

  Fly   354 PLG-FLPSHPASLATNSSL-ALPMIIGATKDASAFIVSRIYDQLARLQSRNVSDYIDVVLRHTAP 416
            ..| |||.||..|..:::. .:|.|||...|...:|:..|:|...:         |:.:.|.|.|
  Rat   314 VDGEFLPKHPQELLASANFHRVPSIIGINNDEYGWILPMIFDSAQK---------IEEITRKTLP 369

  Fly   417 PSEHRLWKQWALREIFTP-----IQEQ----TASLQTVAPGLLELSNYILYRAPVINSISQSYRS 472
                .:.|..||:.:..|     :.|:    |...:|:.....|:....::..|.: .::...||
  Rat   370 ----TVLKSTALKMMLPPECGDLLMEEYMGDTEDPKTLQAQFREMMGDFMFVIPAL-QVAHFQRS 429

  Fly   473 -VPAYLYTFDYRGEHHRFGHLSNPLPFGVDASLSDDSVYL----------FPYPPEASRLNPLDR 526
             .|.|.|.|     .||.....:..|..|.|...|: |:|          ||:..|       :.
  Rat   430 HAPVYFYEF-----QHRSSFFKDVKPPHVKADHGDE-VFLVFGYLVGDIKFPHTEE-------EE 481

  Fly   527 SLSRALVTMWVNFATTGVPNPSSGV--WPQATSEYGPFLRFTNNQQSPLELDPHFGEGI 583
            .|||.::..|.|||..|.|| |.|:  ||....:         :|...|::.|..|..:
  Rat   482 LLSRKIMKYWANFARHGNPN-SEGLPHWPVMDHD---------DQYLQLDIQPSVGRAL 530

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Glt	NP_001245946.1	COesterase	55..579	CDD:278561	153/573 (27%)
		Aes	<146..345	CDD:223730	64/209 (31%)
		RILP-like	<677..>717	CDD:304877
LOC688542	XP_038954018.1	COesterase	30..538	CDD:395084	153/576 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910