Protein Alignment Glt and nlgn3a

DIOPT Version :9

• Sequence 1: NP_001245946.1
• Gene: Glt / 34193
• FlyBaseID: FBgn0001114
• Length: 1026
• Species: Drosophila melanogaster
• Sequence 2: XP_005157256.1
• Gene: nlgn3a / 562702
• ZFINID: ZDB-GENE-071219-1
• Length: 878
• Species: Danio rerio
• Alignment Length: 877
• Identity: 190/877 - (21%)
• Similarity: 301/877 - (34%)
• Gaps: 303/877 - (34%)

  Fly     5 LLVLALCGAQVHAHSVGLRPDYNDYSDEDTRRDWLPEPLKPVPWQSETRYAQPQEAVVQAPEVGQ 69
            |.:|..|...:.....|..|..|                        |:|.:.:.|  :.|...:
Zfish    50 LWILVFCWCMMLVRGQGYYPTVN------------------------TQYGKLRGA--RVPLHSE 88

  Fly    70 ILGISGHKTIANRPVNAFLGIRYGTVGGGLARFQAAQ-PIGYQGRVNATVQSPNCAQ-----FPE 128
            |||          ||:.:||:.|.|...|..||...: |..:.|..|||..:|.|.|     .||
Zfish    89 ILG----------PVDQYLGVPYATPPVGEKRFLPPEPPSSWSGIKNATHFAPVCPQNIHNAVPE 143

  Fly   129 ----------LDRLRLSESRGENVDDCLTLDIYAP------------------------------ 153
                      ||.:..| .:.:| :|||.|:||.|
Zfish   144 IMMPIWFTFNLDIVATS-IQDQN-EDCLYLNIYVPTEDVKRISKECTRKPNKKICRKGGTHSKKQ 206

  Fly   154 -----------------EGANQLPVLVFVHGEMLFDG------GSEEAQPDYVLEK--DVLLVSI 193
                             .||.  ||:|::||....:|      ||       ||..  :|:::::
Zfish   207 GEDLSDNDGDEDEDIRDTGAK--PVMVYIHGGSYMEGTGNMIDGS-------VLASYGNVIVITL 262

  Fly   194 NYRLAPFGFLSALTDELPGNVALSDLQLALEWLQRNVVHFGGNAGQVTLVGQAGGATLAHALSLS 258
            |:|:...||||.......||..|.|...||.|:..|:.:|||::.::|:.|...||:....|:||
Zfish   263 NFRVGVLGFLSTGDQAAKGNYGLLDQIQALRWISENIGYFGGDSNRITVFGSGIGASCVSLLTLS 327

  Fly   259 GRAGNLFQQLILQSGTALNPYLIDNQPLDTLSTFARLARCPPPSINPSAQGLKPLYDCLARLPTS 323
            ..:..||.:.|:|||:||:.:.::.||:......|....|       :......:.|||.:....
Zfish   328 HHSEGLFHRAIIQSGSALSSWAVNYQPVKYTRLLAEKVGC-------NVLDTLDMVDCLRKKSAR 385

  Fly   324 QLVAAFEQLLLQNEHLGLTQLGGFKLVVGDPLGFLPSHPASLATNSS-LALPMIIGATKDASAFI 387
            :||....|....:...|       .::.||   .:|..|..|..... |...:::|..:......
Zfish   386 ELVEQDIQPARYHVAFG-------PVIDGD---VIPDDPEILMEQGEFLNYDIMLGVNQGEGLRF 440

  Fly   388 VSRIYDQLARLQSR----NVSDYIDVV---------LRHTAPPSEHRLWKQWALRE--------- 430
            |..:.|....:...    :|||::|.:         ||.|.    ..::..||.|:
Zfish   441 VENVVDSEDGVSGNDFDFSVSDFVDSLYGYPEGKDTLRETI----KFMYTDWADRDNPETRRKTL 501

  Fly   431 --IFTPIQEQTASLQTVAPGLLELSNYILYRAPVINSISQSYRSVPAYLYTFDYRGEHHRFGHLS 493
              :||       ..|.|.|.::....:..|.:             |.|.|.|     :|....|.
Zfish   502 VALFT-------DHQWVEPSVVTADLHARYGS-------------PTYFYAF-----YHHCQSLM 541

  Fly   494 NPLPFGVDASLSDDSVYLFPYPPEASRLNPLDR----------SLSRALVTMWVNFATTGVPNPS 548
            .|.  ..||:..|:..|:|..|    .:.|.|.          .||..::|.|.|||.||.||..
Zfish   542 KPA--WSDAAHGDEVPYVFGIP----MIGPTDLFPCNFSKNDIMLSAVVMTYWTNFAKTGDPNKP 600

  Fly   549 SGVWPQAT---------------SEYGP----FL------RFTNNQQSP-----LELDPHFGEGI 583
            .   ||.|               |:|.|    :|      |..::.::.     ..|.||    :
Zfish   601 V---PQDTKFIHTKANRFEEVAWSKYNPQDQLYLHIGLKPRVRDHYRATKVAFWKHLVPH----L 658

  Fly   584 YLPNYRVIYKPTTNFSPPITTTTTTTTTTTTTSRPYAYNPYANWQNRPSQQHPNWHPADPEYVRA 648
            |..:....|..||...||:.||..:.:|.....:.:.:|     ..||        |..|.| .:
Zfish   659 YNLHDMFHYTSTTTKVPPLETTQNSLSTKRPNGKAWPFN-----TKRP--------PMSPAY-NS 709

  Fly   649 QEARQQ----------------EFIRE------------------------REQRRREQQLRDQQ 673
            :..::|                ::..|                        |:.:||::|
Zfish   710 ESGKEQWNGEEEPGPLVVENPRDYSTELSVTIAVGASLLFLNVLAFAALYYRKDKRRQEQ----- 769

  Fly   674 RYPQ-QEPREQQDERIRQQREQEERLRQQREQ 704
             :|| ..||......:.:...:||.:..|..|
Zfish   770 -HPQPSPPRATTTNDVNRHAPEEEIMSLQVNQ 800

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Glt	NP_001245946.1	COesterase	55..579	CDD:278561	152/659 (23%)
		Aes	<146..345	CDD:223730	61/253 (24%)
		RILP-like	<677..>717	CDD:304877	7/29 (24%)
nlgn3a	XP_005157256.1	COesterase	69..651	CDD:306613	154/683 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575370
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930