Protein Alignment Glt and nlgn2a

DIOPT Version :9

• Sequence 1: NP_001245946.1
• Gene: Glt / 34193
• FlyBaseID: FBgn0001114
• Length: 1026
• Species: Drosophila melanogaster
• Sequence 2: XP_009301340.1
• Gene: nlgn2a / 556158
• ZFINID: ZDB-GENE-090918-2
• Length: 828
• Species: Danio rerio
• Alignment Length: 872
• Identity: 201/872 - (23%)
• Similarity: 315/872 - (36%)
• Gaps: 253/872 - (29%)

  Fly    68 GQILGISGHKTIANR---PVNAFLGIRYGTVGGGLARFQAAQ-PIGYQGRVNATVQSPNCAQ--- 125
            |::.||.  |.:.|.   ||..:||:.|.|...|..|||..: |..:|...|||..:|.|.|
Zfish    54 GKLRGIK--KELNNEILGPVEQYLGVPYATAPIGDRRFQPPEAPGSWQEVRNATQFAPVCPQNVH 116

  Fly   126 --FPEL-------DRLRLSESRGEN-VDDCLTLDIYAPEGANQL--------------------- 159
              .||:       |.|.::.:..:| .:|||.|::|.|.....|
Zfish   117 GVLPEIMLPVWFTDSLDVAATYIQNQSEDCLYLNVYVPTEDGPLTKKHDESTLNRPRDEDIRDRR 181

  Fly   160 --PVLVFVHGEMLFDG-GSEEAQPDYVLEKDVLLVSINYRLAPFGFLSALTDELPGNVALSDLQL 221
              ||::|:||....:| |:...........:|::|::||||...||||.......||..|.|...
Zfish   182 KKPVMLFIHGGSYMEGTGNMFDASVLAAYGNVIVVTMNYRLGVLGFLSTGDQSAKGNYGLLDQIQ 246

  Fly   222 ALEWLQRNVVHFGGNAGQVTLVGQAGGATLAHALSLSGRAGNLFQQLILQSGTALNPYLIDNQPL 286
            ||.||..|:.||||:..::|:.|...||:..:.|.||..:..|||:.|.|||:|::.:.|..|||
Zfish   247 ALRWLNENIGHFGGDPERITIFGSGAGASCVNLLILSHHSEGLFQRAIAQSGSAISSWSISYQPL 311

  Fly   287 DTLSTFARLARCPPPSINPSAQGLKPLYDCLARLPTSQLVAAFEQLLLQNEHLGLTQLGGFKLVV 351
            ......||...|   :...:|.    |.|||.|....:||.  :.:.....|:....:....:|.
Zfish   312 KYTKILARKVGC---TYGETAD----LVDCLRRKNFRELVD--QDIQPARYHIAFGPVMDGDVVP 367

  Fly   352 GDP-----LGFLPSHPASLATNSSLALPMIIGATKDASAFIVSRIYDQLARLQSRNVSDYID--- 408
            .||     .|...::...:..|....|..:.....::...|.:..:|.       .:|:::|
Zfish   368 DDPEILMQQGEFLNYDLLIGVNQGEGLKFVDDGGTESEEGISAAAFDY-------TISNFVDNLY 425

  Fly   409 ------VVLRHTAPPSEHRLWKQWALRE-----------IFTPIQEQTASLQTVAPGLLELSNYI 456
                  .:||.|.    ..::..||.|:           :||       ..|.|||.:.....:.
Zfish   426 GYPKGKDILRETI----KFMYTDWADRDNGEMRRKTLLALFT-------DHQWVAPAIATAKLHA 479

  Fly   457 LYRAPVINSISQSYRSVPAYLYTFDYRGEHHRFGHLSNPLPFGVDASLSDDSVYLFPYPP-EASR 520
            .|::||             |.|||    .||   ..:...|...||:..|:..|:|..|. .|:.
Zfish   480 DYQSPV-------------YFYTF----YHH---CQTETRPEWADAAHGDEIPYVFGVPMIGATD 524

  Fly   521 LNPL-----DRSLSRALVTMWVNFATTGVPN-------------PS---SGVWPQATSEYGPFL- 563
            |.|.     |..||..::|.|.|||.||.||             |:   ..:|.:..|:...:|
Zfish   525 LFPCNFSKNDIMLSAVVMTYWTNFAKTGDPNLPVPQDTKFIHTKPNRFEEVIWTKFNSKDKQYLH 589

  Fly   564 -----RFTNNQQSP-----LELDPHFGEGIYLPN-YRVIYKPTTNFSPPITTTTTTTTTTTTTSR 617
                 |..:|.::.     |||.||      |.| :..::...|...||.|..|
Zfish   590 IGLKPRIRDNYRANKVAFWLELVPH------LHNLHEEVFSTATTRLPPGTART----------- 637

  Fly   618 PYAYNPYANWQNRPSQQHPNWHPADPEYVRAQEARQQEFIREREQRRREQQLRDQQRYP--QQEP 680
                 |:...|...:.:||  .|..|..:                   :....:|.|:|  ..:.
Zfish   638 -----PHWKGQGPRTTRHP--IPTFPSEL-------------------DPDSSEQPRFPPFPSDT 676

  Fly   681 REQQDE--------------------RIRQQREQEERLRQQREQEERLRQQRELEER-IRQQQER 724
            |:...|                    .:..:|::...:|:     .||..||.:... :...||.
Zfish   677 RDYSTELSVTVAVGASLLFLNILAFAALYYKRDKRHEMRR-----HRLSPQRGVAANDLAHSQEE 736

  Fly   725 EQYEREQQEREQREREELERQQREREQQQPEQQPEYN------PEPVNPWGYPVQEPQ------- 776
            |....:.:..|.....::| ..|..:..:|...|:|.      |:.|     |:..|.
Zfish   737 EIMSLQMKHSEHDAHHDME-PLRPHDILRPACPPDYTLALRRAPDDV-----PLMTPNTITMIPS 795

  Fly   777 --------------PDDNPEDGRLPYP 789
                          |.....:..||:|
Zfish   796 TITGMQPLHAFNTFPTSTGHNNTLPHP 822

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Glt	NP_001245946.1	COesterase	55..579	CDD:278561	159/609 (26%)
		Aes	<146..345	CDD:223730	66/222 (30%)
		RILP-like	<677..>717	CDD:304877	8/59 (14%)
nlgn2a	XP_009301340.1	COesterase	47..608	CDD:306613	155/602 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575614
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.840