DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Glt and angptl3

DIOPT Version :9

Sequence 1:	NP_001245946.1	Gene:	Glt / 34193	FlyBaseID:	FBgn0001114	Length:	1026	Species:	Drosophila melanogaster
Sequence 2:	NP_001011408.1	Gene:	angptl3 / 496885	XenbaseID:	XB-GENE-6258790	Length:	456	Species:	Xenopus tropicalis

Alignment Length:	152	Identity:	33/152 - (21%)
Similarity:	57/152 - (37%)	Gaps:	38/152 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   713 ELEERIRQQQEREQYEREQQEREQREREELERQQREREQQQPEQQPEYNPEPVNPWGYPVQEPQP 777
            :|.|:..:.:|:|:..::...:.|...|||:...|:...|                   |:....
Frog    81 DLSEQTNEIREKEEELKDTTSKLQENNEELKNISRKINSQ-------------------VENLLQ 126

  Fly   778 DD---NPEDGRLPYPSYE--QYGPEGNENLPETDANRNFSEEDREQQQQEQLRREQQEQQEREYQ 837
            |.   ..:.|.|....::  |...||.| :.|..:.:||.|     ||...:|...:..||:..|
Frog   127 DKIHLQAKVGSLEEKLFQMTQGTTEGQE-IKEISSLKNFVE-----QQDVNIRHLLKVVQEQHMQ 185

  Fly   838 L--------QLEREQQEREQQE 851
            |        .||.:..:.:.||
Frog   186 LDHQNVQIKDLEDKLSKADLQE 207

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Glt	NP_001245946.1	COesterase	55..579	CDD:278561
		Aes	<146..345	CDD:223730
		RILP-like	<677..>717	CDD:304877	1/3 (33%)
angptl3	NP_001011408.1	SMC_N	<58..>206	CDD:330553	31/149 (21%)
angptl3	NP_001011408.1	FReD	239..447	CDD:238040
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165162293
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930