DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Glt and nceh1

DIOPT Version :9

Sequence 1:	NP_001245946.1	Gene:	Glt / 34193	FlyBaseID:	FBgn0001114	Length:	1026	Species:	Drosophila melanogaster
Sequence 2:	XP_012818366.1	Gene:	nceh1 / 493371	XenbaseID:	XB-GENE-959943	Length:	409	Species:	Xenopus tropicalis

Alignment Length:	193	Identity:	48/193 - (24%)
Similarity:	77/193 - (39%)	Gaps:	35/193 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   126 FPELD-----RLRLSESRGENVDDCLTLDIYAPEGA---NQLPVLVFVHGEMLFDGGSEEAQPDY 182
            |.:||     .|:::::    |.|.:.:.|:.|..|   |....:|::||.....|.:.....|.
Frog    70 FDQLDPVSSEHLKVTDT----VFDGVEVRIFEPTKAFDKNLKKSIVYIHGGGWALGSARMRSYDS 130

  Fly   183 VLEK-----DVLLVSINYRLAP-FGFLSALTDELPGNVALSDLQLALEWLQRNVVHFGGNAGQVT 241
            :..|     :.::|||.|||.| ..|...|.|.    ||.:...|..|.|    ..:..:..::.
Frog   131 LCRKISEDVNAVVVSIEYRLVPDVHFPEQLNDA----VAATKYFLHPEVL----AEYSVDPSRIA 187

  Fly   242 LVGQAGGATLAHAL--SLSGRAGNL----FQQLI---LQSGTALNPYLIDNQPLDTLSTFARL 295
            :.|.:.|..||.|:  .|:|.:...    .|.||   ||......|....|..:..||.|..:
Frog   188 VSGDSAGGNLAAAVCQQLAGDSSVTTKVKLQALIYPVLQVLDFNTPSYQQNMDMPILSRFVMI 250

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Glt	NP_001245946.1	COesterase	55..579	CDD:278561	48/193 (25%)
		Aes	<146..345	CDD:223730	42/168 (25%)
		RILP-like	<677..>717	CDD:304877
nceh1	XP_012818366.1	Abhydrolase_3	110..382	CDD:400284	38/149 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910