Protein Alignment Glt and Ces3a

DIOPT Version :9

• Sequence 1: NP_001245946.1
• Gene: Glt / 34193
• FlyBaseID: FBgn0001114
• Length: 1026
• Species: Drosophila melanogaster
• Sequence 2: NP_941074.1
• Gene: Ces3a / 382053
• MGIID: 102773
• Length: 571
• Species: Mus musculus
• Alignment Length: 573
• Identity: 154/573 - (26%)
• Similarity: 234/573 - (40%)
• Gaps: 124/573 - (21%)

  Fly    62 VQAPEVGQILG-ISGHKT---IANRPVNAFLGIRYGTVGGGLARFQA-AQPIGYQGRVNATVQSP 121
            |..|||...|| :.|.:.   ..:|.||.||||.:.....|..||.| ..|..::|..:|::..|
Mouse    34 VTQPEVDTPLGRVRGRQVGVKDTDRMVNVFLGIPFAQAPLGPLRFSAPLPPQPWEGVRDASINPP 98

  Fly   122 NCAQFPELDRLRLSESR---GENV------DDCLTLDIYAP---EGANQLPVLVFVHGEMLFDGG 174
            .|.|    |..|:|.||   .|.:      :|||||:||:|   ...::.||:|::||..|..|.
Mouse    99 MCLQ----DVERMSNSRFTLNEKMKIFPISEDCLTLNIYSPTEITAGDKRPVMVWIHGGSLLVGS 159

  Fly   175 SE----EAQPDYVLEKDVLLVSINYRLAPFGFLSALTDELPGNVALSDLQLALEWLQRNVVHFGG 235
            |.    .|...|   .||::|::.|||..|||||.....:|||....|:..||.|:|.|:..|||
Mouse   160 STSHDGSALAAY---GDVVVVTVQYRLGIFGFLSTGDKHMPGNRGFLDVVAALRWVQGNIAPFGG 221

  Fly   236 NAGQVTLVGQAGGATLAHALSLSGRAGNLFQQLILQSGTALNPYLIDNQPLDTLSTFARLARCPP 300
            :...||:.|.:.|..:..:|.||..:..||.:.|.|||..::..|.|.........||....|
Mouse   222 DPNCVTIFGNSAGGIIVSSLLLSPMSAGLFHRAISQSGVVISKILEDLNAWSEAQNFANSVAC-- 284

  Fly   301 PSINPSAQGLKPLYDCLARLPTSQLVAAFEQLLLQNEHLGLTQLGGFKLVVGDPLGFLPSHPASL 365
            .|.:|:     .|..||.:.....|:..      :|.::..|        |.|  .|.|..|..|
Mouse   285 GSASPA-----ELVQCLLQKEGKDLITK------KNVNISYT--------VND--SFFPQRPQKL 328

  Fly   366 ATNSSL-ALPMIIGATKDASAFIVSRIYDQLARLQSRNVSDYID---VVLRHTAPPSE------- 419
            ..|... .:|.::|.|.....:::.:.::.|.:::..:..|.::   .:|.|...|.|
Mouse   329 LANKQFPTVPYLLGVTNHEFGWLLLKFWNILDKMEHLSQEDLLENSRPLLAHMQLPPEIMPTVID 393

  Fly   420 -------HRLWKQWALREIFTPIQEQTASLQTVAPGLLELSNYILYRAPVINSISQSYRSVPAYL 477
                   .....::||:|:.       ..:..|.|.|: .|.|:            .....|.:|
Mouse   394 EYLDNGSDESATRYALQELL-------GDITLVIPTLI-FSKYL------------QDAGCPVFL 438

  Fly   478 YTFDYRGEHHRFGHLSNPLPFGVDASLSDDSVYLFPYP-----------PEASRLNPLDRSLSRA 531
            |.|     .|.....:...|..|.|..|.::.::|..|           |||:.   .::.||..
Mouse   439 YEF-----QHTPSSFAKFKPAWVKADHSSENAFVFGGPFLTDESSLLAFPEATE---EEKQLSLT 495

  Fly   532 LVTMWVNFATTGVPNPSSGV--WPQATSEYGPFLRFTNNQQSPLE--LDPHFG 580
            ::..|..||.||.|| ..|:  |||           .|..:..||  |:|..|
Mouse   496 MMAQWSQFARTGNPN-GKGLPPWPQ-----------LNQLEQYLEIGLEPRTG 536

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Glt	NP_001245946.1	COesterase	55..579	CDD:278561	153/570 (27%)
		Aes	<146..345	CDD:223730	65/205 (32%)
		RILP-like	<677..>717	CDD:304877
Ces3a	NP_941074.1	COesterase	36..547	CDD:278561	153/571 (27%)
		Aes	75..>245	CDD:223730	62/176 (35%)
		Prevents secretion from ER. /evidence=ECO:0000255	568..571

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832499
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840