DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Glt and CG3841

DIOPT Version :9

Sequence 1:	NP_001245946.1	Gene:	Glt / 34193	FlyBaseID:	FBgn0001114	Length:	1026	Species:	Drosophila melanogaster
Sequence 2:	NP_001188759.1	Gene:	CG3841 / 34278	FlyBaseID:	FBgn0032131	Length:	564	Species:	Drosophila melanogaster

Alignment Length:	530	Identity:	155/530 - (29%)
Similarity:	242/530 - (45%)	Gaps:	101/530 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    67 VGQILGISGHKTIANRPVNAFLGIRYGTVGGGLARFQAAQPI---GYQGRV-NATVQSPNCAQFP 127
            :|:|.| ...::..|:.:.||.||||.....|..||  |.|:   .:...| |||..|..|.| |
  Fly    35 LGRIQG-DTMQSFGNKTIYAFRGIRYAQSPVGQLRF--ANPVPETSWGDEVFNATSDSLVCPQ-P 95

  Fly   128 ELDRLRLSESRGENVDDCLTLDIYAPEGANQLPVLVFVHG--EMLFDG-GSEEAQPDYVLEKDVL 189
            .:..| :||       |||.::::.....::.||:|::||  .:|..| .|.||.|.|:|::||:
  Fly    96 GVVSL-MSE-------DCLKINVFTKSFEDKFPVMVYIHGGANVLGSGHSSYEAGPQYLLDQDVV 152

  Fly   190 LVSINYRLAPFGFLSALTDELPGNVALSDLQLALEWLQRNVVHFGGNAGQVTLVGQAGGATLAHA 254
            .|:.||||...||||..:.|..||....|..:||||::.::.||||:...||::|.:.| ::|.:
  Fly   153 FVAFNYRLGALGFLSTNSSETKGNFGFLDQVMALEWVRDHISHFGGDPELVTIIGISAG-SMAVS 216

  Fly   255 LSL-SGRAGNLFQQLILQSGTALNPYLIDNQPLDTLSTFARLAR---CPPPSINPSAQGLKPLYD 315
            |.| |..:..||.:.||.||:|.|.:.|||     |....:|||   |             |:||
  Fly   217 LHLASPLSAGLFHRAILMSGSATNHFDIDN-----LFWTRKLARELGC-------------PMYD 263

  Fly   316 ------CLARLPTSQLV---AAFEQLLLQNEHLGLTQLGGFKLVVGDPLGFLPSHPASLATNSSL 371
                  ||.....:::|   .|:|...|.|..... ::.|.         ||.:||..|....:.
  Fly   264 PTDVVECLRNETWTRIVEVCKAWETYQLVNMKWNY-EIDGH---------FLHNHPTELIKEGNF 318

  Fly   372 -ALPMIIGATKDASAFIVSRIYDQLARLQSRNV-----SDYID-----VVLRHTAPPSEHRLWKQ 425
             .:|::|..|  |:.|    .|:....|:::::     |:::|     .:.||.|...|.  .|.
  Fly   319 NKVPLLISFT--ANEF----DYNANVHLENQHLLHDFASNFVDYAPELFLYRHDAQIGEK--LKD 375

  Fly   426 WALREIFTPIQEQTASLQTVAPGLLELSNYILYRAPVINSISQSYRSVPAYLYTFDYRGEHHRFG 490
            :.|.:..|.|..:  :::..  |.:....||.:....:..::..:  .|.|....||.|:.
  Fly   376 FYLGDNTTEINSE--NIENF--GQIFSDAYIGHGVHRLVQLASHF--TPVYYTRMDYVGDQ---- 430

  Fly   491 HLSNPL-----PFGVDASLSDDSVYLFP---YPPEASRLNPLDRSLSRALVTMWVNFATTGVPNP 547
            .||.||     |.||  ..:||..|:.|   |.| ....|..|..:...|.:.:.:||.||.|..
  Fly   431 SLSAPLNGENKPVGV--GHADDLHYVLPGYWYGP-LMAANDSDVFMMERLTSWFTHFAKTGTPLN 492

  Fly   548 SSGVWPQATS 557
            |:.:||...|
  Fly   493 STDIWPPCNS 502

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Glt	NP_001245946.1	COesterase	55..579	CDD:278561	155/530 (29%)
		Aes	<146..345	CDD:223730	71/214 (33%)
		RILP-like	<677..>717	CDD:304877
CG3841	NP_001188759.1	COesterase	27..528	CDD:278561	155/530 (29%)
CG3841	NP_001188759.1	Aes	<116..>235	CDD:223730	48/119 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45467426
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR43142
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940