Protein Alignment Glt and Ces4a

DIOPT Version :10

• Sequence 1: NP_477504.1
• Gene: Glt / 34193
• FlyBaseID: FBgn0001114
• Length: 1026
• Species: Drosophila melanogaster
• Sequence 2: NP_001099646.1
• Gene: Ces4a / 291955
• RGDID: 1307418
• Length: 563
• Species: Rattus norvegicus
• Alignment Length: 558
• Identity: 152/558 - (27%)
• Similarity: 227/558 - (40%)
• Gaps: 110/558 - (19%)

  Fly    68 GQILGISGHKTIANRPVNAFLGIRYGTVGGGLARFQAAQ-PIGYQGRVNATVQSPNCAQFPELDR 131
            |.:.|...|  :.:.|:..|||:.:.....|..||...: |:.:.|..:||...|:|
  Rat    41 GILQGKQVH--VGDTPIRVFLGVPFSQPPVGTRRFAPPEPPLPWNGIRDATTYPPSC-------- 95

  Fly   132 LRLSESRGENV----------------DDCLTLDIYAP---EGANQLPVLV-FVHGEMLFDGGSE 176
              |.||.|:..                :|||.|::|||   .|...|||:| |..|..|....|.
  Rat    96 --LQESWGQITSMYLNTRKQYEWLHFSEDCLYLNVYAPVLAPGDPLLPVMVWFPGGAFLVGSAST 158

  Fly   177 EAQPDYVLEKDVLLVSINYRLAPFGFLSALTDELPGNVALSDLQLALEWLQRNVVHFGGNAGQVT 241
            ....:......|:||.:.|||...||.|.......||..|.|...||.|:|.|:..|||:...||
  Rat   159 YEGSELAARGKVVLVFLQYRLGILGFFSTGNSHARGNWGLLDQIAALRWVQENIEAFGGDPDSVT 223

  Fly   242 LVGQAGGATLAHALSLSGRAGNLFQQLILQSGTALNPYLIDNQPLDTLSTFARLARCPPPSINPS 306
            |.||:.||.....|.:|..|..||.|.|.|||||:....|.:.||.:....|.||.|...|
  Rat   224 LFGQSAGAMSVSGLLMSPLAQGLFHQAISQSGTAVLKTFITHDPLKSAKKIAHLAGCDHNS---- 284

  Fly   307 AQGLKPLYDCLARLPTSQLVAAFEQLLL--QNEHLGLTQLGGFKLVVGDPLGFLPSHPASLATNS 369
               .|.:..||..||..:::...:::..  .|.|.....:..|...|.|.|.| |..|..|.|..
  Rat   285 ---TKIMVKCLKALPAEKVMLVSKKMTFFRANSHKDPKDIVWFLSPVVDGLVF-PEDPVVLLTRG 345

  Fly   370 SL-ALPMIIGATKD----ASAFIVSRIYDQLARLQSRNVSDYIDVVLRHTAPPSEHRLWKQWALR 429
            .: .:|.::|....    :..|::....:|  |:.::|   ||..:|              |:..
  Rat   346 QVKPVPYLLGVNSAEFEWSLPFLMKLQLNQ--RIMNKN---YITKLL--------------WSCS 391

  Fly   430 EIFTPIQEQTASLQTVAPGLLELS----NYILYRAPVINSISQS---YRSV-----------PAY 476
            .:....:||   :..||...|..:    ::.::|..:|:.:..:   |.::           |.|
  Rat   392 ILLNITEEQ---IPLVAREYLSDAISHHDWKMFRNHLIDLVGDATFVYATLQAARYHRDAGSPVY 453

  Fly   477 LYTFDYRGEHHRFGHLSNPLPFGVDASLSDDSVYLF--PYPPEASRLNPLDRSLSRALVTMWVNF 539
            ||.|    :||..|.:..|...|.|.  .|:..|||  |:...:||..  ::..|..::..|.||
  Rat   454 LYEF----KHHAPGIIVKPRSDGADH--GDELSYLFGSPFSKGSSRGE--EKEFSLQMMKYWANF 510

  Fly   540 ATTGVPNPSS-GVWPQATSEYGPFLRFTNNQQSPLELD 576
            |.||.||... ..||          || :.::..|:||
  Rat   511 AHTGDPNDRELPYWP----------RF-DKEEKYLQLD 537

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Glt	NP_477504.1	COesterase	58..579	CDD:395084	152/558 (27%)
		Casc1_N	681..>717	CDD:464947
Ces4a	NP_001099646.1	COesterase	33..554	CDD:395084	152/558 (27%)