Protein Alignment Glt and cest-9.2

DIOPT Version :10

• Sequence 1: NP_477504.1
• Gene: Glt / 34193
• FlyBaseID: FBgn0001114
• Length: 1026
• Species: Drosophila melanogaster
• Sequence 2: NP_741910.3
• Gene: cest-9.2 / 259729
• WormBaseID: WBGene00007695
• Length: 617
• Species: Caenorhabditis elegans
• Alignment Length: 636
• Identity: 143/636 - (22%)
• Similarity: 236/636 - (37%)
• Gaps: 165/636 - (25%)

  Fly    68 GQILGI------SGHKTIANRPVNAFLGIRYGTVGGGLARFQAAQ-PIGYQGRVNATVQSPNCAQ 125
            |::.||      :.||.:       |..:.:.....|..||...| |..:.|.::|:..||.|
 Worm    29 GRVRGITEWSDDNNHKYM-------FKSVPFAKPPIGKLRFAPPQYPDSWSGVLDASKYSPAC-- 84

  Fly   126 FPELDRLRLSESRGENV-DDCLTLDIYAPEGA--NQLPVLVFVHGEMLFDGGSEEAQPD-YVLEK 186
               |.....:.:..|:| :|||.::|:..|..  ::..|:|:.||. .::|.|....|| ::||:
 Worm    85 ---LSNSSTTSTPQEHVSEDCLYINIFTSEKCLRSKCAVIVYFHGG-AYNGDSATMFPDNFILER 145

  Fly   187 ----DVLLVSINYRLAPFGFL----SALTDELPGNVALSDLQLALEWLQRNVVHFGGNAGQVTLV 243
                ||:|.....||..||.|    |||..|   |:.:.|...||:::...:.:|||:..|||::
 Worm   146 YVAEDVILAIPGVRLGVFGQLYFGPSALLTE---NLFMFDAVQALDFVHNEIPNFGGDPKQVTIM 207

  Fly   244 GQAGGATLAHALSLSGRAG---NLFQQLILQSGTALNPY---LIDNQPL--DTLSTFARLARCPP 300
            |.:.|.||..||..|....   .||||:|:.|||.:..:   |:||..:  :.|..|
 Worm   208 GHSSGGTLVEALGFSNSVDPDLKLFQQIIVLSGTGMFGFYDLLVDNSFIISEKLGCF-------- 264

  Fly   301 PSINPSAQ-----GLKPLYDCLARLPTSQLVAAFEQLLLQNEHLGLTQLGGFKLVVGDPLGFLPS 360
               |.:.:     .:..:.:|:.::...::|.      :|.....:.:|....|:.|.|...| :
 Worm   265 ---NGTQEERTDANIAEILECMRQIDGHEIVG------MQKHMEDVYKLTFKSLLRGAPFMEL-N 319

  Fly   361 HPASLATNSSLALPMIIGATKDASAFIVSR-IYDQLARLQSRN---VSDYIDVVLRHTAPPSEHR 421
            .......||:.....|.|.|:......|.| :|.....|...|   |:.:.|..|
 Worm   320 GKIEKFRNSTSPRNAIFGTTEYEFRNEVERYLYITTTFLDFENPVAVAQHFDDEL---------- 374

  Fly   422 LWKQWALREIFTPIQEQTASLQTVAPGLLELSNYILYRAPVINSISQSYRSVPAYLYTFDYRGEH 486
                  ::.:.|.|.....|:...|.                 :.|.:..:..|.:|.|:.|...
 Worm   375 ------MQNMDTMINGDAVSIFVSAA-----------------AFSSAMANAGADVYLFETRQWP 416

  Fly   487 HRFGHLSNPLPFGVDASLSDDSVYLFPYPPEASR---LNPLDRSLSRALVTMWVNFATTGVPNPS 548
            :.| |:|             |..|......|...   ::.||...|:.|    |||..||.|:|.
 Worm   417 YSF-HVS-------------DMQYFIGIHREVLHTHDMDILDSFYSKLL----VNFTKTGAPSPE 463

  Fly   549 SGVWPQATSEYGPFLRF---TNNQQSPLELD------------------------------PHFG 580
               |.....|...:|..   |.|.:.|:.|:                              |...
 Worm   464 ---WNSLEPEKMNYLELRVDTRNGKGPVMLEGYHDKEVSFWYGDMMDYDRNITKMRQSKGLPREN 525

  Fly   581 EGI--YLPNYRVIYKPTTNFSPPITTTTTTTTTTT---TTSRPYAYNPYAN 626
            :|:  .|..:..|.:|.|.......|....:|:|.   |::..|....:.|
 Worm   526 QGVESQLKYWSSIVEPRTTAHANNATQENISTSTNVLFTSTAQYISREFKN 576

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Glt	NP_477504.1	COesterase	58..579	CDD:395084	132/582 (23%)
		Casc1_N	681..>717	CDD:464947
cest-9.2	NP_741910.3	alpha/beta hydrolases	22..501	CDD:473884	131/559 (23%)