Protein Alignment Glt and cest-8

DIOPT Version :9

• Sequence 1: NP_001245946.1
• Gene: Glt / 34193
• FlyBaseID: FBgn0001114
• Length: 1026
• Species: Drosophila melanogaster
• Sequence 2: NP_001359583.1
• Gene: cest-8 / 182818
• WormBaseID: WBGene00007691
• Length: 605
• Species: Caenorhabditis elegans
• Alignment Length: 591
• Identity: 132/591 - (22%)
• Similarity: 221/591 - (37%)
• Gaps: 144/591 - (24%)

  Fly    68 GQILGISGHKTIANRPVNAFLGIRYGTVGGGLARFQAAQPIG-YQGRVNATVQSPNCAQFPELDR 131
            |::.|::.....||... .|..:.:.....|..||...|.:. :.|.::|:|.|..|     :..
 Worm    26 GKLRGMAEWSDDANHKF-TFKSVPFAKPPIGNLRFAPPQKLDHWDGILDASVYSAAC-----MSN 84

  Fly   132 LRLSESRGENVDDCLTLDIYAPEGA--NQLPVLVFVHGEMLFDGGSEEAQPDYVLEK----DVLL 190
            ..|:.....| :|||.::|:..|..  ::..|:|:.||.......:......::|::    ||:.
 Worm    85 STLTTQSYVN-EDCLYINIFTSEKCLKSKCSVIVYFHGGAYNTESATMFSDRFILDRYVHEDVIF 148

  Fly   191 VSINYRLAPFGFL-----SALTDELPGNVALSDLQLALEWLQRNVVHFGGNAGQVTLVGQAGGAT 250
            |....||..||.|     :.||:    |:.:.|..|||:::...:.:|||:..:||::|.:.|.|
 Worm   149 VIPAVRLGVFGQLYFGPNAYLTE----NLFMFDAILALDFVHNEISNFGGDPEKVTIMGHSSGGT 209

  Fly   251 LAHALSLSGRAG---NLFQQLILQSGTALNPYLIDNQPLDTLSTFARLARCPPPSINPSAQ---- 308
            |..||..|....   .||||:|:.|.|.:  :..|:..:|...|......|    .|.:.:
 Worm   210 LVEALGFSSMVDPELKLFQQMIMLSSTGM--FGFDDLVIDNSFTIVEKLGC----FNGTKEERNT 268

  Fly   309 -GLKPLYDCLARLPTSQLVAAFEQLLLQNEHLGLTQLGGFKLVVGDPLGFLPSHPASLATNSSLA 372
             .:....||:..      :..:|.|.:|.:...:.||....|:.|.|...|..:.|.|..|:|
 Worm   269 VNVAETLDCMRH------IDGYEILRVQQKMELMDQLSFKYLLRGAPFMLLNGNIADLKKNTS-- 325

  Fly   373 LP--MIIGATKDASAFIVSRIYDQLARLQSRNVSDYIDVV-LRHTAPPSEHRLWKQWALREIFTP 434
             |  .|.|.| :...|.|:..|            .||.|. |.:..|.:..|.:....::.:.|.
 Worm   326 -PRNAIFGTT-EHEFFDVTEKY------------LYITVTFLDYENPVAVARNYDGRLMKNMETM 376

  Fly   435 IQEQTA----SLQTVAPGLLE------------------------LSNYILYRAPVINSISQSYR 471
            |...:|    |..|.|..:..                        :.|:..:...:...|..|:.
 Worm   377 ITGDSAAIFVSTATCAAAMANAGADVFLFETRQSYSVHVSDMQYFIGNHCAHNRTIDIDILDSFY 441

  Fly   472 SVPAYLYTFDYRGEHHRFGHLSNPLPFGVDASLSDDSVYLFPYPPEASRLNPLDRSL-SRAL--- 532
            |  ..|..|...|:         |.| |.|             |.:..|:|.|:..: |:|.
 Worm   442 S--KLLTNFTKHGK---------PSP-GWD-------------PVDPGRMNYLELKVDSKARSGP 481

  Fly   533 ----------VTMWVNFATTGVPN-----PSSGVWPQ-----ATSEYGPFLRFTN----NQQSPL 573
                      |:.||...|....|     .|.|:.|:     :..:|..|:.:.|    |||..:
 Worm   482 VMLEGYHAKDVSFWVGEMTEFDQNVSKMRHSEGLPPERQDTKSQRQYWNFIVYQNFDAKNQQKLV 546

  Fly   574 ELDPHF 579
            : ..||
 Worm   547 D-STHF 551

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Glt	NP_001245946.1	COesterase	55..579	CDD:278561	130/589 (22%)
		Aes	<146..345	CDD:223730	53/217 (24%)
		RILP-like	<677..>717	CDD:304877
cest-8	NP_001359583.1	Abhydrolase	19..495	CDD:389770	117/532 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157137
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930