Protein Alignment Glt and cest-2.3

DIOPT Version :10

• Sequence 1: NP_477504.1
• Gene: Glt / 34193
• FlyBaseID: FBgn0001114
• Length: 1026
• Species: Drosophila melanogaster
• Sequence 2: NP_506510.2
• Gene: cest-2.3 / 179918
• WormBaseID: WBGene00013873
• Length: 665
• Species: Caenorhabditis elegans
• Alignment Length: 714
• Identity: 152/714 - (21%)
• Similarity: 259/714 - (36%)
• Gaps: 175/714 - (24%)

  Fly    68 GQILGISGHKTIANRPVNAFLGIRYGTVGGGLARFQAAQPI-GYQGRVNATVQSPNCAQFPELDR 131
            |:||..: :....|:....||||.|.....|..||:..:.: .::|.:......|.|..:
 Worm    29 GKILNAT-YSPFGNQTATVFLGIPYVEPPIGELRFRKPRLLKSWEGVLETKDYKPACMSY----- 87

  Fly   132 LRLSESR---GENVDDCLTLDIYAPEGANQ---LPVLVFVHGEMLFDGGSEEAQPDYVL------ 184
            .|.:...   ||..:|||..:::..:...|   ..|::.|||..|........:|:..:
 Worm    88 WRKTFKNGFVGEISEDCLYANVFTNQYCLQNKNCSVMIVVHGGRLVCESGSAFKPEIFINNFVGQ 152

  Fly   185 EKDVLLVSINYRLAPFGF--LSALTDELPGNVALSDLQLALEWLQRNVVHFGGNAGQVTLVGQAG 247
            ::::::|:.||||..|||  .:..|.:.  |||:.|:..|::|:::.:..||||..::|:.|.:.
 Worm   153 DRNIVVVTFNYRLGVFGFGVFNGETGDT--NVAMYDMLEAVKWVRKEIDQFGGNKDRITMAGHSA 215

  Fly   248 GATLAHALSLSGRAGNLFQQLILQSGTALNPYLIDNQPLDTLSTFARLARCPPPSIN----PSAQ 308
            ||.|....:.|..:..|..|.|:.|.           ||..:|..|........:.|    |...
 Worm   216 GAGLIVDFTSSTLSKGLLHQQIVMSA-----------PLQDISKSANFKGMTIVAQNVGCIPKEY 269

  Fly   309 GLKPL--------YDCLARLPTSQLVAAFEQLLLQNEHLGLTQLGGFKLVVGDPLGFLPSHPASL 365
            |.:.|        |.||.......|:.|  ||.:|...   |...|...|.||   |:..:|.:|
 Worm   270 GFRKLSKTQINKTYLCLQNKSAQDLLHA--QLSMQQNS---TFYFGSPRVDGD---FITDYPDNL 326

  Fly   366 AT-NSSLALPMIIGAT----KDASAFIVSRIYDQLARLQSRNVSDYIDVVLRHTAPPSEHRLWKQ 425
            .. |:...:...||.|    :| |.:|.....|::.....:|:.:::..
 Worm   327 FNFNTIYPINTFIGTTTGELRD-SLYITDPKNDRIKEQLLKNMCEHVGY---------------- 374

  Fly   426 WALREIFTPIQEQTASL------QTVAPGLLELSNYILYRAPVINSISQSYRSVPAYLYTFDYRG 484
                |:|...:|.|...      .|.|..|.:...:......|.|:..::...|  ::|::||:|
 Worm   375 ----ELFEKPEEFTKKCGNYYKNGTDAQFLSDDMEFYSGAIKVANAHKRANSKV--FMYSYDYKG 433

  Fly   485 EHHRF-GHLSNPLPFGVDASLSDDSVYLF-----PYPPEASRLNPLDRSLSRALVTMWVNFATTG 543
            ....| .:|..|.|..     |:|.:|.|     |:..:       |..:.|....|..||....
 Worm   434 AGTAFHKYLEAPSPHH-----SEDLIYTFGTSRGPFVAK-------DYVIERIYSGMLANFINFE 486

  Fly   544 VPNPS-SGVWPQATSEYGPF--LRFTNNQQSPLELDPHFGEGIYLPNYRVIYKPTTNFSPPITTT 605
            .|:|| :..|.|.|.|...:  :.|..|...|...|.::...:...:.......:..|||.:...
 Worm   487 DPSPSKTQQWRQYTQEKREYFLIDFDKNFTMPGMKDHYYTRALDFWSTAGKKSFSERFSPSLDNF 551

  Fly   606 TTTTTTTTTTSRPYAYNPYANWQNRPSQQHPNWHPADPEYVRAQEARQQEFIREREQRRREQQLR 670
            ..:..|.                  |...|.....:.|
 Worm   552 VMSILTD------------------PIVSHLKGVASGP--------------------------- 571

  Fly   671 DQQRYPQQEPREQQDERIRQQREQEERLRQQRE---QEERLRQQRELEERIRQQQEREQYEREQ 731
                          |:.|    ||.|::..:||   :|.:||::.:||::|..|......|.|:
 Worm   572 --------------DKSI----EQFEKVFNERESFLEELKLRRKLKLEKKIGVQMRNSVVEFEK 617

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Glt	NP_477504.1	COesterase	58..579	CDD:395084	129/557 (23%)
		Casc1_N	681..>717	CDD:464947	12/38 (32%)
cest-2.3	NP_506510.2	alpha/beta hydrolases	17..532	CDD:473884	129/564 (23%)