Protein Alignment Glt and cest-2.2

DIOPT Version :9

• Sequence 1: NP_001245946.1
• Gene: Glt / 34193
• FlyBaseID: FBgn0001114
• Length: 1026
• Species: Drosophila melanogaster
• Sequence 2: NP_001256567.1
• Gene: cest-2.2 / 179917
• WormBaseID: WBGene00013874
• Length: 672
• Species: Caenorhabditis elegans
• Alignment Length: 731
• Identity: 140/731 - (19%)
• Similarity: 260/731 - (35%)
• Gaps: 190/731 - (25%)

  Fly    74 SGHKTIANRPVNAFLGIRYGTVGGGLARFQAAQ-PIGYQGRVNATVQSPNCAQFPELDRLRLSES 137
            :.:..:.|:....|.|:.|.....|..||:..: |..:.|.:.|......|          :|:.
 Worm    36 ASYSPLGNQTGIVFFGVPYVEPPVGNLRFRKPRPPKPWDGVLEAKEYKAAC----------MSDQ 90

  Fly   138 R--------GENVDDCLTLDI----YAPEGANQLPVLVFVHGEMLFDGGSEEAQPDYVLE----- 185
            :        |...:|||..::    |..|..| ..|::.:||.......:....|:.::.
 Worm    91 KKTYKNGVGGPVSEDCLYANVFTNQYCLEHKN-CSVMLTIHGGRFVIESASAYDPEIIINNFVGQ 154

  Fly   186 -KDVLLVSINYRLAPFGFLSALTDELPGNVALSDLQLALEWLQRNVVHFGGNAGQVTLVGQAGGA 249
             :::::|:.||||..||......|....|..|.|:...:.|.::.:.:|||:..::|:.|.:.||
 Worm   155 GRNIVVVTFNYRLGLFGLGMLNGDNQDTNFGLYDILEVVRWTRKEIKNFGGDKDRITMQGHSAGA 219

  Fly   250 TLAHALSLSGRAGNLFQQLILQSGTALNPYLIDNQPLDTLSTFARLARCPP-----PSINPSAQG 309
            ....|.|.|..:..|..|.|:.|.:..|  |.....:..|:..||:..|.|     |.:  |...
 Worm   220 VFTAAFSTSPLSKGLIHQQIIMSASMSN--LSKKSNVKELTVVARIVGCLPDEHGFPKL--SNVE 280

  Fly   310 LKPLYDCLARLPTSQLVAAFEQLLLQNE--HLGLTQLGGFKLVVGDPLGFLPSHPASL-ATNSSL 371
            ::..|.|| |..::|.:...:..:|:|.  ::|...:.|...|         .:|.:| ||||..
 Worm   281 VEKAYTCL-RSKSAQQILDAQLYMLRNTTYYIGQGHIDGIYQV---------DYPDNLYATNSIY 335

  Fly   372 ALPMIIGATKDASAFIVSRIYDQLARLQSRNVSDYIDVVLRHTAPPSEHRLWKQWALREI----- 431
            .:..:||.|       .:.:.|....:..:|.... :::|::......:.|:|:  ..|.
 Worm   336 PINTMIGTT-------TAELMDSRYIVDPKNTGKK-EILLQNLCEHIGYELYKE--PEEFSQKCR 390

  Fly   432 -FTPIQEQTASL---QTVAPGLLELSNYILYRAPVINSISQSYRSVPAYLYTFDYRGEHHRFGHL 492
             |....|...||   .....|.::|:|.            .|.:....::|:|||:...:.:..
 Worm   391 NFYKNGEDAKSLGDDMEFYYGAIQLANV------------HSSKDTNVFVYSFDYKEAGNAYKK- 442

  Fly   493 SNPLPFGVDASLS----DDSVYLFPYPPEASRLNPLDRSLSRALVTMWVNFATTGVPNP-SSGVW 552
                   .|.|||    :|..|.|  .......:..|..:......|:.:|...|.|:| ....|
 Worm   443 -------YDKSLSPKHGEDFAYAF--GTNRGNFSTKDYVIEYIYSGMFADFVNFGDPSPLEDQEW 498

  Fly   553 PQATSEYGPFLRFTNNQQSPLELDPHFGEGIYLPNYRVIYKPTT--------------NFSPPIT 603
            .|.|.|        ..:...::.|.:|    .:|..:..|.|..              :|||.:.
 Worm   499 AQYTPE--------KREYFLIDFDKNF----TMPGMKDHYYPKALEFWSTCGSKSFKEHFSPSVD 551

  Fly   604 TTTTTTTTTTTTSRPYAYNPYANWQNRPSQQHPNWHPADPEYVRAQEARQQEFIREREQRRREQQ 668
            ...                 ..|..| |...|.|.:...|:
 Worm   552 IFI-----------------IGNLLN-PIMSHLNHNETGPD------------------------ 574

  Fly   669 LRDQQRYPQQEPREQQDERIRQQREQEERLRQQREQ-EERLRQQRELEERIRQQQEREQYEREQQ 732
                                 :..||.::|..:||: .:.|:..|:||  |:::..|.:..::..
 Worm   575 ---------------------KTFEQFDKLYNEREEFLKLLKAVRKLE--IQKKMWRGRSSKDLM 616

  Fly   733 EREQREREELERQQRE 748
            .:|..:.|::..:::|
 Worm   617 LKELVDLEKINEEEQE 632

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Glt	NP_001245946.1	COesterase	55..579	CDD:278561	113/545 (21%)
		Aes	<146..345	CDD:223730	51/215 (24%)
		RILP-like	<677..>717	CDD:304877	9/40 (23%)
cest-2.2	NP_001256567.1	Abhydrolase	25..534	CDD:389770	117/566 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157015
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.930