Protein Alignment Glt and cest-2.1

DIOPT Version :9

• Sequence 1: NP_001245946.1
• Gene: Glt / 34193
• FlyBaseID: FBgn0001114
• Length: 1026
• Species: Drosophila melanogaster
• Sequence 2: NP_506508.2
• Gene: cest-2.1 / 179916
• WormBaseID: WBGene00013875
• Length: 675
• Species: Caenorhabditis elegans
• Alignment Length: 594
• Identity: 132/594 - (22%)
• Similarity: 236/594 - (39%)
• Gaps: 123/594 - (20%)

  Fly    68 GQILGISGHKTIANRPVNAFLGIRYGTVGGGLARFQAAQ-PIGYQGRVNATVQSPNCAQFPELDR 131
            |:|| .|.:..:.|.....||||.:.....|..||:..: ||.:.|.:......|.|
 Worm    30 GKIL-TSTYSPLGNHTGIGFLGIPFVEPPAGNLRFRKPRPPIPWDGILETKEYKPAC-------- 85

  Fly   132 LRLSESR--------GENVDDCLTLDIYAPEGANQ-------LPVLVFVHGEMLFDGGSEEAQPD 181
              :|:::        |...:|||    ||....||       ..|::.|||..:....:....|:
 Worm    86 --MSDAKKTYKNGVGGPISEDCL----YANVFTNQYCMKRKNCSVMIVVHGGRILTESASAFNPE 144

  Fly   182 YVLE------KDVLLVSINYRLAPFGFLSALTDELPGNVALSDLQLALEWLQRNVVHFGGNAGQV 240
            .::.      :::::|:.||||..|||.....::...||.:.|:..|::|.::.|.:||||..::
 Worm   145 ILVNNFVGQGRNIVVVTFNYRLGTFGFGVLNGEKGDSNVGMFDMLEAVKWTRKEVHNFGGNKDKL 209

  Fly   241 TLVGQAGGATLAHALSLSGRAGNLFQQLILQSGTALNPYLIDNQPLDTLSTFARLARCPPPSINP 305
            |:||.:.|.:|..|.:.|..:..:..|.|:.||.......:.|  ...::..|:.|.|     .|
 Worm   210 TMVGHSAGGSLVGAFTSSPLSKGMLNQQIIMSGALYQMGKLAN--FKGMTAMAQKAGC-----LP 267

  Fly   306 SAQGLKPL--------YDCLARLPTSQLVAAFEQL-LLQNE--HLGLTQLGG-FKLVVGDPLGFL 358
            ...|.:.|        |.||..:...:::.|  || :|||.  ::.:..:.| |.|...|.:  |
 Worm   268 EVFGFRKLSQVRIDKTYSCLRNISAQEVLDA--QLWVLQNTTYYISVPHIDGEFLLNYSDEI--L 328

  Fly   359 PS---HPASL---ATNSSLALPMIIGATKDASAFIVSRIYDQLARLQSRNVSDYIDVVLRHTAPP 417
            .|   ||.:.   .|.:.|..|:.|...|:|         |:...| .:|:.::|..
 Worm   329 ASGTIHPINSMIGTTTAELRDPIYINDLKNA---------DKKEEL-LKNLCEHIGY-------- 375

  Fly   418 SEHRLWKQWALREIFTPIQEQTASLQTV------APGLLELSNYILYRAPVINSISQSYRSVPAY 476
                        |::|..:|.:...|..      |..|.:...:  |...:..:.:.:.::...:
 Worm   376 ------------ELYTEPEEFSRKCQKFYGNGDDAQFLADDMEF--YDGSIKVANAHASKNTKVF 426

  Fly   477 LYTFDYRGEHHRFGHLSNPLPFGVDASLSDDSVYLFPYPPEASRLN--PLDRSLSRALVTMWVNF 539
            :|::||:.....|...:...|    ...|:|.:|:|    ..||.|  ..|..:.:....|:.:|
 Worm   427 MYSYDYKDAGPAFKKYAQAPP----PHHSEDLIYVF----GTSRGNFTEKDYVIEQIYSGMFADF 483

  Fly   540 ATTGVPNPSSGVWPQATSEYGP------FLRFTNNQQSPLELDPHFGEGIYLPNYRVIYKPTTNF 598
            ...|.|:||.   .|...||.|      .:.|..|...|...|.::...:...:.......:.::
 Worm   484 VNFGNPSPSK---EQKWKEYSPEKREYFLIDFDKNFTMPGTRDGYYSRALEFWSTAGTKSFSEHY 545

  Fly   599 SPPITTTTT 607
            ||.:.:.||
 Worm   546 SPSLDSFTT 554

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Glt	NP_001245946.1	COesterase	55..579	CDD:278561	128/564 (23%)
		Aes	<146..345	CDD:223730	55/222 (25%)
		RILP-like	<677..>717	CDD:304877
cest-2.1	NP_506508.2	COesterase	21..533	CDD:365897	128/571 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157066
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.930