Protein Alignment Glt and cest-1.2

DIOPT Version :10

• Sequence 1: NP_477504.1
• Gene: Glt / 34193
• FlyBaseID: FBgn0001114
• Length: 1026
• Species: Drosophila melanogaster
• Sequence 2: NP_506504.2
• Gene: cest-1.2 / 179914
• WormBaseID: WBGene00011364
• Length: 676
• Species: Caenorhabditis elegans
• Alignment Length: 729
• Identity: 150/729 - (20%)
• Similarity: 267/729 - (36%)
• Gaps: 192/729 - (26%)

  Fly    74 SGHKTIANRPVNAFLGIRYGTVGGGLARFQAAQP-IGYQGRVNATVQSPNCAQFPELDRLRLSES 137
            |.:....|:...|||||.|.....|..||:..:| ..:.|.:......|.|          :|.|
 Worm    35 STYSPFGNQSAIAFLGIPYVEPPIGDLRFRKPRPQKTWSGVLETKKFKPAC----------MSNS 89

  Fly   138 R---------GENVDDCLTLDI----YAPEGANQLPVLVFVH-GEMLFDGGS----EEAQPDYV- 183
            .         |...:|||.|::    |..|..| ..|::.|| |..||:..:    |....::|
 Worm    90 TKTYKNGGIGGPISEDCLYLNVLTNQYCLENKN-CSVVIIVHGGGYLFESAATFNHEILVNNFVG 153

  Fly   184 LEKDVLLVSINYRLAPFGFLSALTDELPGNVALSDLQLALEWLQRNVVHFGGNAGQVTLVGQAGG 248
            .::::::|:|||||..|||......|...||.:.|...|::|::|.:..||||..::||.|.:.|
 Worm   154 QDRNIVVVTINYRLGIFGFGHLNGFEGDKNVGIFDTLEAVKWVRREIKQFGGNKDRITLAGHSAG 218

  Fly   249 ATLAHALSLSGRAGNLFQQLILQSGTALNPYLIDNQPLDTLSTFARLARCPPPSIN----PSAQG 309
            |.:..|.::|.....|..|.|:.||...|  :........::..|....|......    |..:
 Worm   219 AGVVAAFTISPLTKGLIHQQIVMSGPMTN--MSKKSNFKGMTAMAERVGCHSKKYGFNKLPEHE- 280

  Fly   310 LKPLYDCLARLPTSQLVAAFEQL-LLQNE--HLGLTQLGGFKLVVGDPLGFLPSHPASLATNSSL 371
            ::.:|.||.:.|..:|:.|  || ||||.  :.|...:.|         .|:..:|.:|.:..|:
 Worm   281 VEQVYSCLRKKPAQELLDA--QLWLLQNSTFYFGAPPVDG---------EFITDYPDNLYSEKSI 334

  Fly   372 -ALPMIIGATK---DASAFIVSRIYDQLARLQS--RNVSDYIDVVLRHTAPPSEHRLWKQWALRE 430
             ::..::|.|.   ..:.:|.:..|.:....::  :|:.|.|.:                    |
 Worm   335 FSINTLLGTTTRELQDTGYISNSNYSKFETKETFLKNLCDQIGI--------------------E 379

  Fly   431 IFTPIQEQTASLQ---TVAPGLLELSNYILYRAPVIN-SISQSYRSVPAYLYTFDYRG------- 484
            |:...::.::..|   ........||:.:.:....|| :.:.:.:....|:|::.|.|
 Worm   380 IYKESEDFSSKCQKWYINGSDSKSLSDDMEFYTQAINLADAHARKGKKVYMYSYAYSGAGPAFKK 444

  Fly   485 ------EHHRFGHLSNPLPFGVDASLSDDSVYLFPYPPEASRLNPLDRSLSRALVTMWVNFATTG 543
                  .||                 |:|.:|.|  ........|.|..:......|:.:|....
 Worm   445 YMKVKSPHH-----------------SEDLIYTF--GTHRGVFAPKDYVIEYIYSGMFADFINFE 490

  Fly   544 VPNPSSGVWPQATSEYGPFLRFTNNQQSPLELDPHFGEGIYLPNYRVIYKPTTNFSPPITTTTTT 608
            .|:||:.         .|:|::|...:....:|  |.:.:.:|..:..|
 Worm   491 DPSPSTD---------QPWLQYTKENKEYFLVD--FDQNLTMPGMKKNY---------------- 528

  Fly   609 TTTTTTTSRPYAYNPYANWQNRPSQQ-HPNWHPADPEYVRAQEARQQEFIREREQRRREQQLRDQ 672
                      || ..|..|.....:. ...|.|:...::......
 Worm   529 ----------YA-KAYEFWSTAGQKSFKEEWSPSLDTFIITNLVA-------------------- 562

  Fly   673 QRYPQQEPREQQDERIRQQREQEERLRQQRE---QEERLRQQRELE--ERIRQQQER-------- 724
               |.....:|....:.:..||.|.|:.:||   :.|:|:::.|||  ..|::.::|
 Worm   563 ---PIITHMDQITFDVDKTVEQMEILKIERENFLKSEKLKRKSELEMSRWIKKGRKRVINKRMGF 624

  Fly   725 ---EQYEREQQERE 735
               |..|.|:.|.:
 Worm   625 MPVEIIENEESESD 638

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Glt	NP_477504.1	COesterase	58..579	CDD:395084	122/554 (22%)
		Casc1_N	681..>717	CDD:464947	12/40 (30%)
cest-1.2	NP_506504.2	COesterase	18..536	CDD:395084	128/602 (21%)