Protein Alignment Glt and cest-24

DIOPT Version :9

• Sequence 1: NP_001245946.1
• Gene: Glt / 34193
• FlyBaseID: FBgn0001114
• Length: 1026
• Species: Drosophila melanogaster
• Sequence 2: NP_504613.1
• Gene: cest-24 / 179017
• WormBaseID: WBGene00020891
• Length: 658
• Species: Caenorhabditis elegans
• Alignment Length: 621
• Identity: 149/621 - (23%)
• Similarity: 249/621 - (40%)
• Gaps: 129/621 - (20%)

  Fly    49 QSETRYAQPQEAVVQAPEVGQILGISGHKTIANRPVNAFLGIRYGTVGGGLARFQAAQPIGYQGR 113
            :||....:.|:.:::...|         ||......:.|.||.|.....|..|||..||......
 Worm    92 KSENAIVRVQQGLLEGFRV---------KTAKGDLCDVFHGIPYAEPPVGELRFQKPQPPKAWEG 147

  Fly   114 VNATVQSPNCAQFPEL--DRLRLSESRGENVDDCLTLDIYAPE--GANQLPVLVFVHGEMLFDGG 174
            :....:.||.:...|:  |:...|.::.|   |||.|:::||:  ...:.|||.::||     ||
 Worm   148 IRKCNKYPNRSIHKEMPWDKALPSANQSE---DCLYLNVFAPKIREDKKYPVLFYIHG-----GG 204

  Fly   175 SEEAQPDYVLE----------------KDVLLVSINYRLAPFGFLSALTDELPGNVALSDLQLAL 223
                   ||::                :::::|:.:|||...||||...|..|||..|.|:..|:
 Worm   205 -------YVMDSAERYTAKNICKLLVSREIIVVTFHYRLGFLGFLSTGDDVCPGNYGLFDMLEAM 262

  Fly   224 EWLQRNVVHFGGNAGQVTLVGQAGGATLAHALSLSGRAGNLFQQLILQSGTALNPY----LIDNQ 284
            .|:..|:..|||:...:||.||:.||..|..||.|.....||::.|:..|   |.|    ...|.
 Worm   263 RWVHANISSFGGDPENITLSGQSAGAAAADLLSFSPLTKGLFKRKIVMGG---NSYCHWATTSNH 324

  Fly   285 PL-DTLSTFA-RLARCPPPSINPSAQGLKPLYDCLARLPTSQL--VAAFEQLLLQNEHLGLTQLG 345
            .: :....:| ||...|..:.....:....:::....||||:|  ...|...:.:...|.|.
 Worm   325 DIREYCKKWAKRLGWKPQLNYANKREESVDIFNFFNGLPTSKLGMTMFFSNTIFKECQLPLA--- 386

  Fly   346 GFKLVVGDPLGFLPSHPASLATNSSLALPMIIGATKDASAFIVSRIYDQLARLQSRNVSDYIDVV 410
              .::.|:   .|| |...:...:...:|.::|. .:..|.:...|  .|.|...:.::..|||:
 Worm   387 --PVIDGE---ILP-HDLKVLRETQEHVPSLVGG-GEYEALLFCAI--GLLRGTEKEINSAIDVL 442

  Fly   411 LRHTAPPSEHRLWKQWALREIFTPIQEQTASLQTVAPGL-LELSNYILYRAPVINSISQSY---- 470
            .|      ::||.:        :.|:..|..:...:|.| .:.....::...:|:.|..:|
 Worm   443 SR------KNRLSR--------SKIEAMTEKVYGDSPALRADSKARKMFFVQLISDIFANYGNYR 493

  Fly   471 -------RSVPAYLYTFDYRGEHHRFGHLSNPLPFGVDASLSDDSVYLFP--YPPEASRLNPLDR 526
                   |.|..|.|:||::.: ..:|.|.:.:||......|:.| |||.  |......:|..|:
 Worm   494 FMRDCQQRGVECYGYSFDHQSK-QMWGWLQHVVPFTGGTHTSELS-YLFDCNYMSAPLGMNKTDK 556

  Fly   527 SLSRALVTMWVNFATTGVPN-PSSGV--WPQ-------------------ATSEYGPFLRFTNNQ 569
            .:|......:.||...|.|| |:|.:  |.:                   .|:.||  .|..|
 Worm   557 VVSGMTADYFTNFVKFGTPNGPNSQLPKWERISPDDEHMKLISIKPEPEMKTTVYG--YRMQN-- 617

  Fly   570 QSPLELDPHFGEGIYLPNYRVIYKPTTNFSPPITTT 605
                 .:.|.|. :|....:..:.|..||.|.|.::
 Worm   618 -----FEDHLGM-LYEEKDKSPFSPRGNFKPSIVSS 647

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Glt	NP_001245946.1	COesterase	55..579	CDD:278561	139/587 (24%)
		Aes	<146..345	CDD:223730	62/224 (28%)
		RILP-like	<677..>717	CDD:304877
cest-24	NP_504613.1	COesterase	97..608	CDD:278561	134/565 (24%)
		Aes	<183..>285	CDD:223730	34/113 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D206516at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920