Protein Alignment Glt and Ces3b

DIOPT Version :9

• Sequence 1: NP_001245946.1
• Gene: Glt / 34193
• FlyBaseID: FBgn0001114
• Length: 1026
• Species: Drosophila melanogaster
• Sequence 2: NP_653094.2
• Gene: Ces3b / 13909
• MGIID: 3644960
• Length: 571
• Species: Mus musculus
• Alignment Length: 657
• Identity: 163/657 - (24%)
• Similarity: 249/657 - (37%)
• Gaps: 175/657 - (26%)

  Fly    61 VVQAPEVGQILG-ISGHKT---IANRPVNAFLGIRYGTVGGGLARFQA-AQPIGYQGRVNATVQS 120
            |:| |||...|| :.|.:.   ..:|.||.||||.:.....|..||.| ..|..::|..:|::..
Mouse    34 VIQ-PEVDTPLGRVRGRQVGVKDTDRMVNVFLGIPFAQAPVGPLRFSAPLPPQPWEGVRDASINP 97

  Fly   121 PNCAQFPELDRLRLSESR---GENV------DDCLTLDIYAP---EGANQLPVLVFVHGEMLFDG 173
            |.|.|    |..::..||   .|.:      :|||||:||:|   ...::.||:|::||..|. .
Mouse    98 PMCLQ----DVEKMINSRFGLNEKIKIFPISEDCLTLNIYSPTEITAGDKRPVMVWIHGGSLL-V 157

  Fly   174 GSEEAQPDYVLEK--DVLLVSINYRLAPFGFLSALTDELPGNVALSDLQLALEWLQRNVVHFGGN 236
            ||..:|....|..  ||::|::.|||..|||||.....:|||....|:..||.|:|.|:..|||:
Mouse   158 GSSTSQDGSALAAYGDVVVVTVQYRLGIFGFLSTGDKHMPGNRGFLDVVAALRWVQGNIAPFGGD 222

  Fly   237 AGQVTLVGQAGGATLAHALSLSGRAGNLFQQLILQSGTALNPYLIDNQPLDTLSTFARLARCPPP 301
            ...||:.|.:.|..:..:|.||..:..||.:.|.|||......:.|.:|......||....|  .
Mouse   223 PNCVTIFGNSAGGMIVSSLFLSPISAGLFHRAISQSGIVTTIMMEDMKPWPEAQNFANSVAC--G 285

  Fly   302 SINPSAQGLKPLYDCLARLPTSQLVAAFEQLLLQNEHLGLTQLGGFKL--VVGDPLGFLPSHPAS 364
            |.:|                 ::||    |.|||.|...|.:.....:  :|.|  .|.|..|..
Mouse   286 SASP-----------------AELV----QCLLQKEGKDLIKQKNVNISYIVND--SFFPQRPEK 327

  Fly   365 LATNSSL-ALPMIIGATKDASAFIVSRIYDQLARLQSRNVSDYIDVVLRHTA----PPSEHRLWK 424
            |..:... .:|.::|.|.....:::.:..:.|.:|:..:..|.:::.....|    ||
Mouse   328 LLADQQFPTVPYLLGVTNHEFGWLLLKSLNILDKLEHLSREDLLEISRPFLAIMEVPP------- 385

  Fly   425 QWALREIFTPI--------QEQTASLQTVAPGLLELSNYILYRAPVINSISQSYRSV--PAYLYT 479
                 ||...:        .:|:|:..    ...||...|.:..|.:| .|:..|..  |.:||.
Mouse   386 -----EIMPTVIDEYLDNGSDQSATRY----AFQELLGDISFIIPTLN-FSKYLRDAGCPVFLYE 440

  Fly   480 FDY-------------RGEHHRFGHLSNPLPFGVDASLSDDSVYLFPYPPEASRLNPLDRSLSRA 531
            |.:             :.:|..    .|...||......:.|:..||...|.      ::.||..
Mouse   441 FQHTPSSFAKFKPAWVKADHAS----ENSFVFGGPFLTDESSLLAFPEATEE------EKQLSLT 495

  Fly   532 LVTMWVNFATTGVPNPSSGV--WPQATSEYGPFLRFTNNQQSPLELDPHFGEGIYLPNYRVIYKP 594
            ::..|..||.||.|| ..|:  |||           .|..:..||:......|:.|...|:.:
Mouse   496 MMAQWSQFARTGNPN-GKGLPPWPQ-----------LNQLEQYLEIGLESRTGVKLKKGRLQF-- 546

  Fly   595 TTNFSPPITTTTTTTTTTTTTSRPYAYNPYANWQNRPSQQHPNWHPADPEYVRAQEARQQEFIRE 659
                                            |.....::...||
Mouse   547 --------------------------------WTETLPRKIQEWH-------------------- 559

  Fly   660 REQRRRE 666
            ||||.|:
Mouse   560 REQRSRK 566

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Glt	NP_001245946.1	COesterase	55..579	CDD:278561	152/568 (27%)
		Aes	<146..345	CDD:223730	67/203 (33%)
		RILP-like	<677..>717	CDD:304877
Ces3b	NP_653094.2	COesterase	36..547	CDD:278561	154/614 (25%)
		Aes	75..>245	CDD:223730	60/174 (34%)
		Prevents secretion from ER. /evidence=ECO:0000255	568..571

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832482
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.840