DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Glt and AgaP_AGAP006723

DIOPT Version :9

Sequence 1:	NP_001245946.1	Gene:	Glt / 34193	FlyBaseID:	FBgn0001114	Length:	1026	Species:	Drosophila melanogaster
Sequence 2:	XP_309021.4	Gene:	AgaP_AGAP006723 / 1270336	VectorBaseID:	AGAP006723	Length:	605	Species:	Anopheles gambiae

Alignment Length:	570	Identity:	139/570 - (24%)
Similarity:	219/570 - (38%)	Gaps:	114/570 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 QSETRYAQPQEAVVQAPEVGQILGISGHKTIAN-RPVNAFLGIRYGTVGGGLARFQAAQPIGYQG 112
            ||...| .|...::.....|.|.|....  :.| :|...|.||.|.....|..||.:.:||.
Mosquito    21 QSAQEY-DPSARIMVKVLQGSIYGTKDR--LPNGKPYYCFKGIPYAKPPVGKLRFASPEPID--- 79

  Fly   113 RVNATVQSPNCAQFPELDRLRLSESRGENV--------DDCLTLDIYAP--------EGANQLPV 161
              ...|...:|::       ..|...|.:|        :|.|.:::|.|        .|....||
Mosquito    80 --RYPVSYLDCSR-------ERSSCLGRDVITREITGSEDGLFVNVYTPALGREVSSTGTPLAPV 135

  Fly   162 LVFVHGEMLFDGGSEEAQ--PDYVLEKDVLLVSINYRLAPFGFLSALTDELPGNVALSDLQLALE 224
            :||.||..:..|..:.:.  |||::::.|::.::||||...|||......:.||..|.|.:|||:
Mosquito   136 MVFFHGGGMTGGNGDSSMYLPDYLVQEGVVVATVNYRLGVLGFLCLPQAGIEGNAGLKDQRLALQ 200

  Fly   225 WLQRNVVHFGGNAGQVTLVGQAGGAT--LAHALSLSGRAGNLFQQLILQSGTALNPYLIDNQPLD 287
            |:::||..|||:...|||.|.:.|.:  |.|.  .|..:...|.:.|.||.|.....:...:|.:
Mosquito   201 WIRQNVSTFGGDPNNVTLFGASSGGSNVLMHC--FSDLSQPYFHKAIAQSATIFADLIYQTEPEE 263

  Fly   288 TLSTFARLARCPPPSINPSAQG-LKPLYDCLARLPTSQLVAAFEQLLLQNEHLGLTQLGGF---- 347
            ...:.||:....    ..|.:| |..|.|    :|..:|..| :.|:|.:......|:..|
Mosquito   264 RARSLARIFGYE----GTSDEGVLATLRD----VPARRLYEA-QFLVLSDREREYEQIFQFPFTA 319

  Fly   348 ---------KLVVGDPLGFL--PSH---PASLATNSSLALPMIIGATKDASAF------IVSRIY 392
                     .::|..|:.:|  |:.   |.....|....:..::...|:.|.:      .:.|.:
Mosquito   320 VIEREQSTDPVLVKTPMEYLREPNRMRVPVLCGYNDKEGMLELVDMIKNLSVYNARPEKFICRSF 384

  Fly   393 DQLARLQSRNVSDYIDVVLRHTAPPSEHRLWKQWALREIFTPIQEQTASLQTVAPGLLE---LSN 454
            |          .||.....|  |...|.|       |..|.......|:|..:...|.:   :..
Mosquito   385 D----------VDYFSSAAR--ALGEEMR-------RHYFGEASISRANLDRLVDLLTDRFVVGY 430

  Fly   455 YILYRAPVINSISQSYRSVPAYLYTFDYRG------EHHRFGHLSNPLPFGVDASLSDDSVYLFP 513
            |:|.:.     .|:...:.|.|.|.|.|.|      |..:|.||..       |...|:..|||.
Mosquito   431 YVLCKL-----WSEHQPATPLYSYRFAYEGSLNKGKELLKFQHLPG-------ACHIDEVYYLFS 483

  Fly   514 YPPEASRLNPLDRS--LSRALVTMWVNFATTGVPNPSSGVWPQATSEYGP 561
            .|...:.:.|.|.:  :.:.:|.||.|||....|.|.:...|....::.|
Mosquito   484 SPLLRTEIPPSDPAYRMRQLMVRMWTNFAKHSNPTPPTEHEPGLPCQWEP 533

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Glt	NP_001245946.1	COesterase	55..579	CDD:278561	136/564 (24%)
		Aes	<146..345	CDD:223730	62/211 (29%)
		RILP-like	<677..>717	CDD:304877
AgaP_AGAP006723	XP_309021.4	Abhydrolase	34..564	CDD:304388	135/556 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D206516at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010