Protein Alignment Glt and Nlgn1

DIOPT Version :9

• Sequence 1: NP_001245946.1
• Gene: Glt / 34193
• FlyBaseID: FBgn0001114
• Length: 1026
• Species: Drosophila melanogaster
• Sequence 2: XP_038957495.1
• Gene: Nlgn1 / 116647
• RGDID: 621117
• Length: 863
• Species: Rattus norvegicus
• Alignment Length: 704
• Identity: 178/704 - (25%)
• Similarity: 263/704 - (37%)
• Gaps: 199/704 - (28%)

  Fly    68 GQILGISGHKTIANR---PVNAFLGIRYGTVGGGLARFQAAQPIGYQGRV-NATVQSPNCAQ--- 125
            |:|.||.  |.:.|.   ||..|||:.|.....|..|||..:|......: |||..:|.|.|
  Rat    60 GKIRGIK--KELNNEILGPVIQFLGVPYAAPPTGEHRFQPPEPPSPWSDIRNATQFAPVCPQNII 122

  Fly   126 ---FPE----------LDRLRLSESRGENVDDCLTLDIYAP------------------------ 153
               .||          ||  .:|....:..:|||.|:||.|
  Rat   123 DGRLPEVMLPVWFTNNLD--VVSSYVQDQSEDCLYLNIYVPTEDVKRISKECARKPGKKICRKGG 185

  Fly   154 ----------------------EGANQLPVLVFVHGEM-------LFDGGSEEAQPDYVLEK--D 187
                                  :.....||:|::||..       |:||.        ||..  :
  Rat   186 PLTKTQTDDLGDNDRAEDEDIRDSGGPKPVMVYIHGGSYMEGTGNLYDGS--------VLASYGN 242

  Fly   188 VLLVSINYRLAPFGFLSALTDELPGNVALSDLQLALEWLQRNVVHFGGNAGQVTLVGQAGGATLA 252
            |:::::||||...||||.......||..|.||..||.|...|:..|||:..::|:.|...|.:..
  Rat   243 VIVITVNYRLGVLGFLSTGDQAAKGNYGLLDLIQALRWTSENIGFFGGDPLRITVFGSGAGGSCV 307

  Fly   253 HALSLSGRA-GN--------LFQQLILQSGTALNPYLIDNQPLDTLSTFARLARCPPPSINPSAQ 308
            :.|:||..: ||        |||:.|.||||||:.:.:..||       |:.||.....:..:..
  Rat   308 NLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTALSSWAVSFQP-------AKYARILATKVGCNVS 365

  Fly   309 GLKPLYDCLARLPTSQLVAAFEQLLLQNEHLGLTQLGGFKLVVGDPLGFLPSHPASLATNSS-LA 372
            ....|.:||.:.|       :::|:.|:.......:....::.||   .:|..|..|..... |.
  Rat   366 DTVELVECLQKKP-------YKELVDQDVQPARYHIAFGPVIDGD---VIPDDPQILMEQGEFLN 420

  Fly   373 LPMIIGATKDASAFIVSRIYDQLARLQSRN----VSDYID---------VVLRHTAPPSEHRLWK 424
            ..:::|..:......|..|.|....:.:.:    ||:::|         .|||.|.    ..::.
  Rat   421 YDIMLGVNQGEGLKFVENIVDSDDGVSASDFDFAVSNFVDNLYGYPEGKDVLRETI----KFMYT 481

  Fly   425 QWALREIFTPIQEQTASLQTVAPGLLELSNYILYRAPVINS--ISQSYRSVPAYLYTFDYRGEHH 487
            .||.|.          :.:|....||.|.....:.||.:.:  :..::.| |.|.|.|    .||
  Rat   482 DWADRH----------NPETRRKTLLALFTDHQWVAPAVATADLHSNFGS-PTYFYAF----YHH 531

  Fly   488 RFGHLSNPLPFGVDASLSDDSVYLFPYP---PEASRLNPL-----DRSLSRALVTMWVNFATTGV 544
               ..::.:|...||:..|:..|:...|   |  :.|.|.     |..||..::|.|.|||.||.
  Rat   532 ---CQTDQVPAWADAAHGDEVPYVLGIPMIGP--TELFPCNFSKNDVMLSAVVMTYWTNFAKTGD 591

  Fly   545 PNPSSGVWPQATS---------EYGPFLRFTNNQQSPLE--LDPHFGEGIYLPNYR--------- 589
            ||...   ||.|.         |...:.|::...|..|.  |.|...|     :||
  Rat   592 PNQPV---PQDTKFIHTKPNRFEEVAWTRYSQKDQLYLHIGLKPRVKE-----HYRANKVNLWLE 648

  Fly   590 -VIYKPTTNFSPPITTTTTTTTTTTTTSRPYAYN--------PYANWQNRPSQQ 634
             |.:....|.....|:|||...:|..|.||...|        |.|. |:.|.||
  Rat   649 LVPHLHNLNDISQYTSTTTKVPSTDITLRPTRKNSTPVTSAFPTAK-QDDPKQQ 701

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Glt	NP_001245946.1	COesterase	55..579	CDD:278561	158/629 (25%)
		Aes	<146..345	CDD:223730	65/262 (25%)
		RILP-like	<677..>717	CDD:304877
Nlgn1	XP_038957495.1	COesterase	52..646	CDD:395084	161/646 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166336129
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.840