Protein Alignment Glt and ache

DIOPT Version :10

• Sequence 1: NP_477504.1
• Gene: Glt / 34193
• FlyBaseID: FBgn0001114
• Length: 1026
• Species: Drosophila melanogaster
• Sequence 2: NP_571921.1
• Gene: ache / 114549
• ZFINID: ZDB-GENE-010906-1
• Length: 634
• Species: Danio rerio
• Alignment Length: 595
• Identity: 164/595 - (27%)
• Similarity: 247/595 - (41%)
• Gaps: 123/595 - (20%)

  Fly    54 YAQPQEAVVQAPEVGQILGISGHKTIANRP-VNAFLGIRYGTVGGGLARFQAAQPIGYQGRVNAT 117
            :||.:..:|.|..:|::.|.  ...:.:|. |.|||||.|.....|..||:.|:|......|...
Zfish    22 FAQAEPDLVVATRLGRVQGT--RLPVPDRSHVIAFLGIPYAEPPIGKRRFKRAEPKKPWNNVFEA 84

  Fly   118 VQSPN-CAQF-----PELDRLRLSESRGENVDDCLTLDIYAP--EGANQLPVLVFVHGEMLFDGG 174
            .:..| |.||     |....:.:........:|||.|:::.|  .....|.|:|:::|...:.|.
Zfish    85 KEFSNACYQFVDTSYPGFPGIEMWNPNRVMSEDCLYLNVWVPPTPRPQNLTVMVWIYGGGFYSGS 149

  Fly   175 SEEAQPD---YVLEKDVLLVSINYRLAPFGFLSAL--TDELPGNVALSDLQLALEWLQRNVVHFG 234
            |.....|   ....:.|::||:|||:..|||| ||  :.:.||||.|.|.:|||:|:|.|:..||
Zfish   150 SSLDVYDGRYLAYTEKVVVVSMNYRVGAFGFL-ALNGSSDAPGNVGLYDQRLALQWVQENIHFFG 213

  Fly   235 GNAGQVTLVGQAGGATLA--HALSLSGRAGNLFQQLILQSGTALNPYLIDNQPLDTLSTF----- 292
            ||..|||:.|::.||...  |.||...|.  ||.:.|||||       :.|.|..|: ||
Zfish   214 GNPKQVTIFGESAGAASVGMHVLSPDSRP--LFTRAILQSG-------VPNTPWATV-TFDEARR 268

  Fly   293 -----ARLARCPPPSINPSAQGLKPLYDCLARLPTSQLVAAFEQLLLQNEHLGLTQLGGFKLV-V 351
                 .:|..|       :......|.|||......:|:....|:      |..:.|..|..| |
Zfish   269 RTTKLGKLVGC-------TWGNDTELIDCLRNKHPQELIDQEWQV------LPWSSLFRFSFVPV 320

  Fly   352 GDPLGFLPSHPASLATNSSLALPMII-----------------GATKDASAFIVSRIYDQLARLQ 399
            .|.: |.|..|.::.::.:.....|:                 |.:||..:.|....:.:..::.
Zfish   321 VDGV-FFPDTPDAMISSGNFKYTQILLGVNQDEGSYFLLYGAPGFSKDNESLISREDFLESVKMG 384

  Fly   400 SRNVSD--YIDVVLRHTAPPSEHRLWKQWAL-------REIFTPIQE------QTASL----QTV 445
            ..:.:|  ...|:|::|....|:...|....       :.:..|:|.      |.|:|    ...
Zfish   385 VPHANDIGLEAVILQYTDWMDENNGQKNRDAMDDIVGDQNVICPLQHFAKSYAQYAALHAQSSAA 449

  Fly   446 APGLLELSNYILYRAPVINSISQSYRSVPAYLYTFDYRGEHHRFGHLSNPLPFGVDASLSDDSVY 510
            |||.|...|    ..|...:...|:.:|  |||.||     ||..:|:.|...||......:  :
Zfish   450 APGTLGWGN----SGPTGYNSGNSHGAV--YLYLFD-----HRASNLAWPEWMGVIHGYEIE--F 501

  Fly   511 LFPYPPEASRLN--PLDRSLSRALVTMWVNFATTGVPN-------PSSGVWPQATSEYGPFLRFT 566
            :|..|.| .|||  ..:..|||.::..|.|||.||.||       .|...|||          |:
Zfish   502 VFGLPLE-KRLNYTAEEEKLSRRIMRYWANFARTGNPNVNTDGTMDSRRRWPQ----------FS 555

  Fly   567 NNQQSPLELD 576
            .|:|..:.|:
Zfish   556 ANEQKHVGLN 565

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Glt	NP_477504.1	COesterase	58..579	CDD:395084	162/591 (27%)
		Casc1_N	681..>717	CDD:464947
ache	NP_571921.1	COesterase	27..583	CDD:395084	162/590 (27%)
		AChE_tetra	598..631	CDD:430146