Protein Alignment Glt and Ache

DIOPT Version :9

• Sequence 1: NP_001245946.1
• Gene: Glt / 34193
• FlyBaseID: FBgn0001114
• Length: 1026
• Species: Drosophila melanogaster
• Sequence 2: XP_036020624.1
• Gene: Ache / 11423
• MGIID: 87876
• Length: 616
• Species: Mus musculus
• Alignment Length: 604
• Identity: 169/604 - (27%)
• Similarity: 248/604 - (41%)
• Gaps: 120/604 - (19%)

  Fly    68 GQILGISGHKTIANRPVNAFLGIRYGTVGGGLARFQAAQP-IGYQGRVNATVQSPNCAQ-----F 126
            ||:.||  .......||:|||||.:.....|..||...:| ..:.|.::||.....|.|     :
Mouse    46 GQLRGI--RLKAPGGPVSAFLGIPFAEPPVGSRRFMPPEPKRPWSGVLDATTFQNVCYQYVDTLY 108

  Fly   127 PELDRLRLSESRGENVDDCLTLDIYA--PEGANQLPVLVFVHGEMLFDGGSEEAQPD--YVLE-K 186
            |..:...:.....|..:|||.|:::.  |..|:..|||::::|...:.|.:.....|  ::.: :
Mouse   109 PGFEGTEMWNPNRELSEDCLYLNVWTPYPRPASPTPVLIWIYGGGFYSGAASLDVYDGRFLAQVE 173

  Fly   187 DVLLVSINYRLAPFGFLSAL--TDELPGNVALSDLQLALEWLQRNVVHFGGNAGQVTLVGQAGGA 249
            ..:|||:|||:..|||| ||  :.|.||||.|.|.:|||:|:|.|:..|||:...|||.|::.||
Mouse   174 GAVLVSMNYRVGTFGFL-ALPGSREAPGNVGLLDQRLALQWVQENIAAFGGDPMSVTLFGESAGA 237

  Fly   250 TLA--HALSLSGRAGNLFQQLILQSGTALNPYLIDNQPLDTLST---------FARLARCPPPSI 303
            ...  |.|||..|  :||.:.:|||||       .|.|..|:|.         .|||..|||...
Mouse   238 ASVGMHILSLPSR--SLFHRAVLQSGT-------PNGPWATVSAGEARRRATLLARLVGCPPGGA 293

  Fly   304 NPSAQGLKPLYDCLARLPTSQLVAAFEQLLLQNEHLGLTQLGGFKLVVGDPLGFLPSHPASLA-T 367
            ..:.   ..|..||...|...||.....:|.|.   .:.:.....:|.||   ||...|.:|. |
Mouse   294 GGND---TELIACLRTRPAQDLVDHEWHVLPQE---SIFRFSFVPVVDGD---FLSDTPEALINT 349

  Fly   368 NSSLALPMIIGATKD-ASAFIV------SRIYDQL---------ARLQSRNVSDYI--DVVLRHT 414
            .....|.:::|..|| .|.|:|      |:..:.|         .|:.....||..  .|||.:|
Mouse   350 GDFQDLQVLVGVVKDEGSYFLVYGVPGFSKDNESLISRAQFLAGVRIGVPQASDLAAEAVVLHYT 414

  Fly   415 APPSEHRLWKQWALREIFTPIQEQTASL----QTVAPGLLELSNYILYRAPVINSISQSYRSVPA 475
                      .|...|..|.:::..:::    ..|.| :.:|:..:         .:|..|   .
Mouse   415 ----------DWLHPEDPTHLRDAMSAVVGDHNVVCP-VAQLAGRL---------AAQGAR---V 456

  Fly   476 YLYTFDYRGEHHRFGHLSNPLPFGVDASLSDDSVYLFPYPPEASRLNPLDRSLSRALVTMWVNFA 540
            |.|.|:     ||...|:.||..||......:.::..|..|..:.... :|..::.|:..|.|||
Mouse   457 YAYIFE-----HRASTLTWPLWMGVPHGYEIEFIFGLPLDPSLNYTTE-ERIFAQRLMKYWTNFA 515

  Fly   541 TTGVPN----PSSGVWPQATSEYGPFLRFTNNQQSPLELDPHFGEGIYLPNYRVIYKPT----TN 597
            .||.||    ..|..||..|:        ...|...|.|.|       |...|.:...|    ..
Mouse   516 RTGDPNDPRDSKSPQWPPYTT--------AAQQYVSLNLKP-------LEVRRGLRAQTCAFWNR 565

  Fly   598 FSPPITTTTTTTTTTTTTS 616
            |.|.:.:.|.|....|..|
Mouse   566 FLPKLLSATATEAPCTCPS 584

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Glt	NP_001245946.1	COesterase	55..579	CDD:278561	160/561 (29%)
		Aes	<146..345	CDD:223730	74/216 (34%)
		RILP-like	<677..>717	CDD:304877
Ache	XP_036020624.1	COesterase	37..563	CDD:395084	163/581 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832849
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840