DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Glt and LOC107987423

DIOPT Version :9

Sequence 1:	NP_001245946.1	Gene:	Glt / 34193	FlyBaseID:	FBgn0001114	Length:	1026	Species:	Drosophila melanogaster
Sequence 2:	XP_016885725.1	Gene:	LOC107987423 / 107987423	-ID:	-	Length:	286	Species:	Homo sapiens

Alignment Length:	291	Identity:	65/291 - (22%)
Similarity:	117/291 - (40%)	Gaps:	67/291 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   316 CLARLPTSQLVAAFEQLLLQNEHLGLTQLGGFKLVVGDP------LGFLPSHPASLATNSSL--- 371
            ||.:....:|:    :..|:.:.|.|.       :.|||      ||.:......|.|...|
Human     4 CLRQKTEEELL----ETTLKMKFLSLD-------LQGDPRESQPLLGTVIDGMLLLKTPEELQAE 57

  Fly   372 ----ALPMIIGATKDASAFIVSRIYDQLARLQSRNVSD-YIDVVLRHTAPPSEHRLWKQWAL--- 428
                .:|.::|..|....:::.      .:|.|..:|: .:|   :.||   ...|||.:.|
Human    58 RNFHTVPYMVGINKQEFGWLIP------MQLMSYPLSEGQLD---QKTA---MSLLWKSYPLVCI 110

  Fly   429 -REIFTPIQEQ-------TASLQTVAPGLLELSNYILYRAPVINSISQSYR--SVPAYLYTFDYR 483
             :|:.....|:       |...:.:   .|:|...:::..|.: .:::::|  ..|.|:|.|.||
Human   111 AKELIPEATEKYLGGTDDTVKKKDL---FLDLIADVMFGVPSV-IVARNHRDAGAPTYMYEFQYR 171

  Fly   484 GEHHRFGHLSNPLPFGVDASLSDD--SVYLFPYPPEASRLNPLDRSLSRALVTMWVNFATTGVPN 546
            ....     |:..|..|.....|:  ||:..|:..|.:....:  .||:.::..|.|||..|.||
Human   172 PSFS-----SDMKPKTVIGDHGDELFSVFGAPFLKEGASEEEI--RLSKMVMKFWANFARNGNPN 229

  Fly   547 PSSGV--WPQATSEYGPFLRFTNNQQSPLEL 575
             ..|:  ||:...:.| :|:...|.|:..:|
Human   230 -GEGLPHWPEYNQKEG-YLQIGANTQAAQKL 258

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Glt	NP_001245946.1	COesterase	55..579	CDD:278561	65/291 (22%)
		Aes	<146..345	CDD:223730	6/28 (21%)
		RILP-like	<677..>717	CDD:304877
LOC107987423	XP_016885725.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D206516at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.010