DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Glt and LOC100334697

DIOPT Version :9

Sequence 1:	NP_001245946.1	Gene:	Glt / 34193	FlyBaseID:	FBgn0001114	Length:	1026	Species:	Drosophila melanogaster
Sequence 2:	XP_002661384.2	Gene:	LOC100334697 / 100334697	-ID:	-	Length:	576	Species:	Danio rerio

Alignment Length:	676	Identity:	158/676 - (23%)
Similarity:	255/676 - (37%)	Gaps:	216/676 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 VLALC---------GAQVHAHSVGLRPDYNDYSDEDTRRDWLPEPLKPVPWQSETRYAQPQEAVV 62
            ||:||         .||::..:|              .|...|..|.|         .||.. ..
Zfish     7 VLSLCVFFLTDSRSDAQINVSAV--------------LRSVSPSALTP---------GQPSR-TA 47

  Fly    63 QAPEV----GQILGISGHKTIANRPVNAFLGIRYGTVGGGLARFQAAQPI-GYQGRVNATVQSPN 122
            ..|::    |.:.|:...|:.      .|.||.:.....|.:|::|.:|: .::|..:|:.....
Zfish    48 DGPKLLIKDGLVQGLLLDKSY------VFYGIPFADPPVGTSRWKAPRPVTPWKGVYDASFPRAA 106

  Fly   123 CAQF---PELDRL--RLSESRGENVDDCLTLDIYAPEGAN-------QLPVLVFVHG-------- 167
            |.|.   |..|..  ::||       |||.|:::.|...:       .|||::::||
Zfish   107 CMQACIGPIADDCPKKVSE-------DCLYLNVFVPLSVDLATPLLQPLPVMLWIHGGDFIAGSA 164

  Fly   168 -EMLFDGG--SEEAQPDYVLEKDVLLVSINYRLAPFGFLSALTD---ELPGNVALSDLQLALEWL 226
             :.|:||.  |...|        .::|||.|||..||||.:..|   ...||..:.|.|.||.|:
Zfish   165 SKPLYDGRFISNYTQ--------TVIVSIAYRLGAFGFLVSGKDPKSTAVGNYGILDQQAALIWV 221

  Fly   227 QRNVVHFGGNAGQVTLVGQAGGA--TLAHALSLSGRAGNLFQQLILQSGTALNPYLIDNQPLDTL 289
            |:|:..|||:..:||:.|::.||  ...|.:..|.:.  ||:|.:.||.....|.....:.|...
Zfish   222 QQNIAAFGGDPSRVTIFGESAGAQSVSLHLMIQSSKP--LFKQAVFQSLPFSIPLKTRRESLKLG 284

  Fly   290 STFARLARCPPPSINPSAQGLKPLYDCLARLPTSQLVAAFEQLLLQNEHLGLTQLGGFKLVVGDP 354
            ..||:.|.|       |.:.:|    ||..|....::.|  |:...:           |||  :|
Zfish   285 KHFAKAANC-------SLEDMK----CLQSLSAEDVLHA--QIKTSS-----------KLV--NP 323

  Fly   355 LGFL-------PSHPASLATNSSLAL----------PMIIGATKDASAFIVSRIYDQLARLQSRN 402
            ..||       |.....|....:::.          |:::|.|.:.....|..::       .:.
Zfish   324 FRFLEVFEIWGPFIDGELIKEQAVSAFQKGHWQKEKPVLLGTTSEEGVIFVYGVF-------KKP 381

  Fly   403 VSDYIDVVLRHTAPPSEHRLWKQWALREI--FTPIQEQTASLQTVAPGLLELSNYILY------- 458
            || .::..:..||      ::||.|::.:  :.|:.........:|.   .:::||.:
Zfish   382 VS-AVECTIYTTA------IFKQHAIKILRKYLPLYSDADRRDMLAQ---IVTDYIFWCPSRRSA 436

  Fly   459 RAPVINSISQSYRSVPAYLYTFDYRGE-----------HHRFGHLSNPLPFGVD-ASLSDDSVYL 511
            ||.|::..|       |::|.||....           :.|..| ...|||..| ||:::.|
Zfish   437 RAAVLSGSS-------AWMYVFDQVSSDPRVWSGVSSCYQRVCH-GAELPFVFDSASVANFS--- 490

  Fly   512 FPYPPEASRLNPLDRSLSRALVTMWVNFATTGVP-----NPS--SGV--------WPQATSEYGP 561
                     :.|.::.||..::..|..||.||.|     .||  ||.        ||..|:..|.
Zfish   491 ---------MTPAEKLLSNRVLCYWGGFAHTGNPTGETRRPSDISGFCRQQRPPSWPSYTANRGW 546

  Fly   562 FLRFTNNQQSPLELDPH----FGEGI 583
            .:       ..|...||    :||.|
Zfish   547 MI-------MNLTAHPHSQAGYGEDI 565

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Glt	NP_001245946.1	COesterase	55..579	CDD:278561	144/613 (23%)
		Aes	<146..345	CDD:223730	61/221 (28%)
		RILP-like	<677..>717	CDD:304877
LOC100334697	XP_002661384.2	COesterase	44..569	CDD:278561	145/616 (24%)
LOC100334697	XP_002661384.2	Aes	<138..>245	CDD:223730	37/114 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575395
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR43142
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.030