Protein Alignment Glt and nlgn4x

DIOPT Version :10

• Sequence 1: NP_477504.1
• Gene: Glt / 34193
• FlyBaseID: FBgn0001114
• Length: 1026
• Species: Drosophila melanogaster
• Sequence 2: XP_017946613.1
• Gene: nlgn4x / 100329189
• XenbaseID: XB-GENE-6036018
• Length: 833
• Species: Xenopus tropicalis
• Alignment Length: 952
• Identity: 216/952 - (22%)
• Similarity: 326/952 - (34%)
• Gaps: 321/952 - (33%)

  Fly    38 WLPEPLKPV---------PWQS--ETRY----AQPQEAVV----------QAPEVGQILGISGHK 77
            |||....||         .|.:  ..|:    .|.|..:|          :.|...:|||
 Frog     9 WLPLIFTPVCVLVNSNLLLWIAALAVRFTIVDCQAQHPIVPTNYGKIRGTRTPLPIEILG----- 68

  Fly    78 TIANRPVNAFLGIRYGTVGGGLARFQAAQ-PIGYQGRVNATVQSPNCAQF--------------- 126
                 ||..:||:.|.:...|..|||..: |..:.|..|||..:|.|.||
 Frog    69 -----PVEQYLGVPYASPPTGERRFQPPEPPSSWTGIKNATQFAPVCPQFLDERSLLNDMLPIWF 128

  Fly   127 -PELDRLRLSESRGENVDDCLTLDIYAP--EGA------------------------NQLPVLVF 164
             ..||.: :|..:.:| :|||.|:||.|  :||                        |:.||:|:
 Frog   129 TANLDTV-VSYVQDQN-EDCLYLNIYVPTEDGATTKKQADDIANNDRGEDEDIHDPNNKKPVMVY 191

  Fly   165 VHGEMLFDG------GSEEAQPDYVLEKDVLLVSINYRLAPFGFLSALTDELPGNVALSDLQLAL 223
            :||....:|      ||..|.     ..:|:::::||||...||||.......||..|.|...||
 Frog   192 IHGGSYMEGTGNMIDGSILAS-----HGNVIVITVNYRLGVLGFLSTGDQAAKGNYGLLDQIQAL 251

  Fly   224 EWLQRNVVHFGGNAGQVTLVGQAGGATLAHALSLSGRAGNLFQQLILQSGTALNPYLIDNQP--- 285
            .|::.|:..|||:..:||:.|...||:....|:||..:..|||:.|:||||||:.:.::.||
 Frog   252 RWIEENIGAFGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALSSWAVNYQPAKY 316

  Fly   286 ------------LDTLSTFARLARC---------PPPSINPSAQGLK--PLYDCLARLPTSQLVA 327
                        |||:.    |..|         ...||.|:...:.  |:.|       ..::.
 Frog   317 TRILADKVGCDMLDTID----LVECLRDKNYKELIQQSITPATYHIAFGPVID-------GDVIP 370

  Fly   328 AFEQLLLQNEH-------LGLTQLGGFKLVVGDPLGFLPSHPASLATNSSLALPMIIGATKDASA 385
            ...|:|::...       ||:.|..|.|.|.|            :..|..       |.:.....
 Frog   371 DDPQILMEQGEFLNYDIMLGVNQGEGLKFVDG------------MVDNED-------GVSLSDFD 416

  Fly   386 FIVSRIYDQLARLQSRNVSDYID--VVLRHTAPPSEHRLWKQWALRE-----------IFTPIQE 437
            |.||...|        |:..|.:  ..||.|.    ..::..||.:|           :||
 Frog   417 FSVSNFVD--------NLYGYPEGKDTLRETI----KFMYTDWADKENPETRRKTLVALFT---- 465

  Fly   438 QTASLQTVAPGLLELSNYILYRAPVINSISQSYRSVPAYLYTFDYRGEHHRFGHLSNPLPFGVDA 502
               ..|.|||.:.....:..|.:             |.|.|.|    .||....:.   |...|:
 Frog   466 ---DHQWVAPAVATADLHARYGS-------------PTYFYAF----YHHCQSEMK---PTWADS 507

  Fly   503 SLSDDSVYLFPYPPEASRLNPL----------DRSLSRALVTMWVNFATTGVPNPSSGVWPQAT- 556
            :..|:..|:|..|    .:.|.          |..||..::|.|.|||.||.||...   ||.|
 Frog   508 AHGDEVPYVFGIP----MIGPTELFNCNFSKNDVMLSAVVMTYWTNFAKTGDPNKPV---PQDTK 565

  Fly   557 --------------SEYGP----FL------RFTNNQQSP-----LELDPHFGEGIYLPNYRVI- 591
                          |:|.|    :|      |..::.::.     |||.||      |.|...|
 Frog   566 FIHTKPNRFEEVAWSKYDPKDQLYLHIGLKPRVRDHYRATKVAFWLELVPH------LHNLNEIF 624

  Fly   592 -YKPTTNFSPPITTTTTTTTTTTTTSRPYAYNPYANWQNRPSQQHPNWHPADPEYVRAQEARQ-- 653
             |..||...||...|:....|.....:|           |.:.:.|...||:    .|:|.::
 Frog   625 QYVSTTTKVPPPDMTSYPHVTRRPPLKP-----------RITTKRPAMTPAN----NAKETQKNV 674

  Fly   654 --QEFIREREQRRREQQLR-----------------DQQRYPQQEPREQQDERIRQQREQEERLR 699
              :..|...::|....:|.                 ....|.:.:.|.:...|...||.....:.
 Frog   675 LGENTIITEDKRDYSTELSVTIAVGASLLFLNILAFAALYYKKDKRRHETHRRPSPQRNTTNDIA 739

  Fly   700 QQREQEERLRQQRELEERIRQQQEREQYEREQQEREQREREELERQQREREQQQPEQQPEYNPEP 764
            ..:.:|....|.::||         ..:|.|..:.....|...........::.|:..|...|..
 Frog   740 HIQNEEIMSLQMKQLE---------HDHECEALQAHDTLRLTCPPDYTLTLRRSPDDIPLMTPNT 795

  Fly   765 VN--PWGYPVQEPQPDDNPEDGRLPYPSYEQY-GPEGNENLP 803
            :.  |            |...|..|..::..: |.:.:.|||
 Frog   796 ITMIP------------NTLTGMQPLHTFNTFSGGQNSTNLP 825

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Glt	NP_477504.1	COesterase	58..579	CDD:395084	164/665 (25%)
		Casc1_N	681..>717	CDD:464947	8/35 (23%)
nlgn4x	XP_017946613.1	COesterase	46..610	CDD:395084	159/656 (24%)