Protein Alignment Glt and nlgn1

DIOPT Version :10

• Sequence 1: NP_477504.1
• Gene: Glt / 34193
• FlyBaseID: FBgn0001114
• Length: 1026
• Species: Drosophila melanogaster
• Sequence 2: XP_017949302.2
• Gene: nlgn1 / 100329186
• XenbaseID: XB-GENE-6041753
• Length: 859
• Species: Xenopus tropicalis
• Alignment Length: 694
• Identity: 181/694 - (26%)
• Similarity: 266/694 - (38%)
• Gaps: 184/694 - (26%)

  Fly    68 GQILGISGHKTIANR---PVNAFLGIRYGTVGGGLARFQAAQPIGYQGRV-NATVQSPNCAQ--- 125
            |::.|..  |.:.|.   ||..|||:.|.....|..|||..:|....|.: |:|..:|.|.|
 Frog    60 GKVRGFK--KELNNEILGPVVQFLGVPYAAPPIGERRFQPPEPPTMWGDIKNSTQFAPVCPQNIV 122

  Fly   126 ---FPE----------LDRLRLSESRGENVDDCLTLDIYAP------------------------ 153
               .||          ||  .:|....:..:|||.|:||.|
 Frog   123 GGRLPEVMLPVWFTNNLD--VVSSYVQDQSEDCLYLNIYVPTEDVKRISKECARKPGKKICRKEG 185

  Fly   154 -------------EGANQ---------LPVLVFVHGEM-------LFDGGSEEAQPDYVLEK--D 187
                         |||..         .||:|::||..       :|||.        ||..  :
 Frog   186 PLTKKQTDDLGDNEGAEDEDIRDSGGPKPVMVYIHGGSYMEGTGNVFDGS--------VLASYGN 242

  Fly   188 VLLVSINYRLAPFGFLSALTDELPGNVALSDLQLALEWLQRNVVHFGGNAGQVTLVGQAGGATLA 252
            |:::::||||...||||.......||..|.||..||.|...|:..|||:..::|:.|...||:..
 Frog   243 VIVITVNYRLGVLGFLSTGDQASKGNYGLLDLIQALRWTSENIGFFGGDPLRITVFGSGAGASCV 307

  Fly   253 HALSLSGRA-GN--------LFQQLILQSGTALNPYLIDNQPLDTLSTFARLARCPPPSINPSAQ 308
            :.|:||..: ||        |||:.|.||||||:.:.:..||.......|....|     |.|..
 Frog   308 NLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTALSSWAVSFQPAKYARILATKVGC-----NMSDS 367

  Fly   309 GLKPLYDCLARLPTSQLVAAFEQLLLQNEHLGLTQLGGFKLVVGDPLGFLPSHPASLATNSS-LA 372
            |  .|.:||.:.|..:||....|.:..:...|       .::.||   .:|..|..|..... |.
 Frog   368 G--ELVECLQKKPYRELVDQDIQPVRYHIAFG-------PVIDGD---VIPDDPQVLMEQGEFLN 420

  Fly   373 LPMIIGATKDASAFIVSRIYDQLARLQSRN----VSDYIDVVLRHTAPPSEHR-----LWKQWAL 428
            ..:::|..:......|....|....:.|.:    ||:::|.:..:|......|     ::..||.
 Frog   421 YDIMLGVNQGEGLKFVESTVDHEDGVSSSDFDFAVSNFVDNLYGYTEGKDILRETIKFMYTDWAD 485

  Fly   429 REIFTPIQEQTASLQTVAPGLLELSNYILYRAPVINS--ISQSYRSVPAYLYTFDYRGEHHRFGH 491
            |.          :.:|....||.|.....:.||.:.:  :..::.| |.|.|.|    .||   .
 Frog   486 RN----------NPETRRKTLLALFTDHQWVAPAVATADLHSNFGS-PTYFYAF----YHH---C 532

  Fly   492 LSNPLPFGVDASLSDDSVYLFPYP---PEASRLNPL-----DRSLSRALVTMWVNFATTGVPNPS 548
            .::.:|...|||..|:..|:|..|   |  :.|.|.     |..||..::|.|.|||.||.||..
 Frog   533 QTDQVPAWADASHGDEIPYVFGIPMIGP--TELFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNQP 595

  Fly   549 SGVWPQATS---------EYGPFLRFTNNQQSPLE--LDPHFGE-------GIYL---PNYRVIY 592
            .   ||.|.         |...:.|::...|..|.  |.|...|       .::|   |...|:.
 Frog   596 V---PQDTKFIHTKPNRFEEVAWTRYSQKDQLYLHIGLKPRVKEHYRATKVNLWLELVPRLHVMN 657

  Fly   593 KPTTNFSP--PITTTTTTTTTTTTTSRPYAYNPYA--NWQNRPS 632
            ..||...|  .||:..|.:.|...||   |:...:  |::.:||
 Frog   658 DLTTTKGPSTDITSKPTGSNTVPVTS---AFPTVSEDNFKQKPS 698

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Glt	NP_477504.1	COesterase	58..579	CDD:395084	164/625 (26%)
		Casc1_N	681..>717	CDD:464947
nlgn1	XP_017949302.2	COesterase	52..646	CDD:395084	165/637 (26%)